Expert Report: Advancing OECD TG 309 biodegradation testing
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Expert Report: Advancing OECD TG 309 biodegradation testing

09.09.2026 read more
Framework for Risk Assessment of Plastic Additives
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Framework for Risk Assessment of Plastic Additives

23.07.2026 read more
Repeat Dose Toxicity testing workshop: From concept to application
07.05.2026 - 08.05.2026

Repeat Dose Toxicity testing workshop: From concept to application

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Planetary boundary for novel entities
06.05.2026 - 07.05.2026

Planetary boundary for novel entities

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New ECETOC expert report: Advancing OECD TG 309 biodegradation testing
390508

New ECETOC expert report: Advancing OECD TG 309 biodegradation testing

A new expert meeting report is now available on the ECETOC website exploring how OECD TG 309 can be made more robust and environmentally relevant for chemical persistence assessment. The report ref...
09.09.2026 Read more
We’re Hiring: Join the ECETOC Team as a Trainee!
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We’re Hiring: Join the ECETOC Team as a Trainee!

Are you passionate about science, regulatory toxicology, and making a real-world impact at the intersection of industry, academia, and policy? ECETOC is excited to announce that we’re looking for a...
25.08.2026 Read more
Epigenetics – Roland Buesen
01.06.2016

Epigenetics – Roland Buesen

See the video
HSSD Tool

HSSD Tool

This software was developed by a consortium of partners to facilitate the uptake of novel approaches to estimate aquatic threshold concentrations (e.g. the concentration at which 5% of the species are exposed above their EC50, HC5).
03.10.2025 Read more
The Human Exposure Assessment Tools Database (heatDB)

The Human Exposure Assessment Tools Database (heatDB)

heatdb is a public directory of exposure data sources as well as available tools for exposure
03.10.2025 Read more
NanoApp

NanoApp

ECETOC’s NanoApp is a tool designed to define the boundaries of sets of similar nanoforms and to generate a justification for the REACH registration.
03.10.2025 Read more
Targeted Risk Assessment (TRA)

Targeted Risk Assessment (TRA)

The Targeted Risk Assessment (TRA) estimates exposures to workers, consumers and the environment that arise during a series of events.
03.10.2025 Read more
TRA Task Force – Worker branch

TRA Task Force – Worker branch

Why? The Worker TRA Task Force has been active since 2019, delivering projects that advance the scientific basis of the Worker Targeted Risk Assessment (TRA) tool. Its overarching objective is to e...
04.08.2026 Read more
Immunotoxicity assessment: Addressing Challenges and Advancing Methodologies [Workshop → Task Force]​

Immunotoxicity assessment: Addressing Challenges and Advancing Methodologies [Workshop → Task Force]​

Why? Regulatory assessment of immunotoxic properties of chemicals is a complex and challenging task​ Limited regulatory guidance exists​ Lack of industry and regulatory knowledge​...
30.07.2026 Read more
Chronic fish case studies towards an IATA

Chronic fish case studies towards an IATA

Why? Hazard and safety assessments for the pelagic compartment often rely on in vivo studies using a single fish species, raising ethical concerns and uncertainty in terms of extrapolation....
24.02.2026 Read more
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Publications
TR 138 – ECETOC Guidance on Dose Selection
Technical Report

TR 138 – ECETOC Guidance on Dose Selection

10.03.2021 Read more
TR 136 – Assessment Factors to Derive DNELs – Critical Evaluation of the Status Quo
Technical Report

TR 136 – Assessment Factors to Derive DNELs – Critical Evaluation of the Status Quo

23.02.2021 Read more
Workshop Report no.37 – Online workshop on the scientific feasibility of exposure-based adaptations in the regulatory setting
Workshop Report

Workshop Report no.37 – Online workshop on the scientific feasibility of exposure-based adaptations in the regulatory setting

16.02.2021 Read more
Toward a science-based testing strategy to identify maternal thyroid hormone imbalance and neurodevelopmental effects in the progeny – part I: which parameters from human studies are most relevant for toxicological assessments?
Article

Toward a science-based testing strategy to identify maternal thyroid hormone imbalance and neurodevelopmental effects in the progeny – part I: which parameters from human studies are most relevant for toxicological assessments?

09.02.2021 Read more
TR 135 – Exploring community-based environmental hazard assessment of mixtures using mode-of-action based approaches
Technical Report

TR 135 – Exploring community-based environmental hazard assessment of mixtures using mode-of-action based approaches

12.05.2020 Read more
Workshop Report no.36 – Microbiome Expert Workshop (Porto, 8-9 July 2019)
Workshop Report

Workshop Report no.36 – Microbiome Expert Workshop (Porto, 8-9 July 2019)

Workshop Report No. 36 April 2020 ISSN-2078-7219-036 (online)...
30.04.2020 Read more
ECETOC 2019 Annual Report
Annual Report

ECETOC 2019 Annual Report

Overview of the 2019 activities and output of ECETOC, the Centre for Chemical Safety Assessment. 2019 was a year in which ECETOC successfully started to deliver on the new vision and strategy. This...
06.04.2020 Read more
TR 134 – Sufficiency of aquatic hazard data for environmental risk assessment in sediment and soil
Technical Report

TR 134 – Sufficiency of aquatic hazard data for environmental risk assessment in sediment and soil

03.04.2020 Read more
Toward an Improved Understanding of the Ingestion and Trophic Transfer of Microplastic Particles: Critical Review and Implications for Future Research
Article

Toward an Improved Understanding of the Ingestion and Trophic Transfer of Microplastic Particles: Critical Review and Implications for Future Research

28.03.2020 Read more
TR 133-2 – The Applicability of Analytical Tools, Test Methods and Models for Polymer Risk Assessment
Technical Report

TR 133-2 – The Applicability of Analytical Tools, Test Methods and Models for Polymer Risk Assessment

24.03.2020 Read more
TR 133-1 – The ECETOC Conceptual Framework for Polymer Risk Assessment (CF4Polymers)
Technical Report

TR 133-1 – The ECETOC Conceptual Framework for Polymer Risk Assessment (CF4Polymers)

05.06.2019 Read more
ECETOC 2018 Annual Report
Annual Report

ECETOC 2018 Annual Report

Overview of the 2018 activities and output of the European Centre for Ecotoxicology and Toxicology of Chemicals (ECETOC)....
21.03.2019 Read more
TR 132 – An evaluation of the challenges and limitations associated with aquatic toxicity and bioaccumulation studies for sparingly soluble and manufactured particulate substances
Technical Report

TR 132 – An evaluation of the challenges and limitations associated with aquatic toxicity and bioaccumulation studies for sparingly soluble and manufactured particulate substances

28.12.2018 Read more
Workshop Report no.35 – Advances in (environmental) exposure modelling: Bridging the gap between research and application. 4-5 May 2017, Brussels
Workshop Report

Workshop Report no.35 – Advances in (environmental) exposure modelling: Bridging the gap between research and application. 4-5 May 2017, Brussels

WR 35 Advances in (environmental) exposure modelling: Bridging the gap between research and application. 4-5 May 2017, Brussels Published March 2018 ISSN-2078-7219-35 (online) D-2018-3001-253...
15.03.2018 Read more
ECETOC 2017 Annual Report
Annual Report

ECETOC 2017 Annual Report

Overview of the 2017 activities and output of the European Centre for Ecotoxicology and Toxicology of Chemicals (ECETOC)...
13.03.2018 Read more
TR 131 – Targeted Risk Assessment: Further Explanation of the Technical Basis of the TRA v3.1
Technical Report

TR 131 – Targeted Risk Assessment: Further Explanation of the Technical Basis of the TRA v3.1

09.02.2018 Read more
Workshop Report no.34 – Improvement of the OECD 306 screening test
Workshop Report

Workshop Report no.34 – Improvement of the OECD 306 screening test

...
20.09.2017 Read more
Article

New Approach to Weight-of-Evidence Assessment of Ecotoxicological Effects in Regulatory Decision-Making

19.05.2017 Read more
TR 129: Biodegradation Default Half-Life Values in the Light of Environmentally Relevant Biodegradation Studies – Analysis of the ECETOC Biodegradation Data Base
Technical Report

TR 129: Biodegradation Default Half-Life Values in the Light of Environmentally Relevant Biodegradation Studies – Analysis of the ECETOC Biodegradation Data Base

07.04.2017 Read more
TR 130: The ECETOC Seven Steps for the Identification of Endocrine Disrupting Properties (ECETOC 7SI-ED)
Technical Report

TR 130: The ECETOC Seven Steps for the Identification of Endocrine Disrupting Properties (ECETOC 7SI-ED)

The ECETOC 7SI-ED is recommended as a tool to assess whether or not a substance possesses endocrine disrupting properties. It is based on robust scientific principles and has been designed to be pract...
31.03.2017 Read more
Workshop Report 33: Chemical respiratory allergy: clinical information and how to use it and improve it. October 27-28 October 2016, Madrid
Workshop Report

Workshop Report 33: Chemical respiratory allergy: clinical information and how to use it and improve it. October 27-28 October 2016, Madrid

The workshop identified various areas that can drive improvements in the identification, classification and risk characterisation of respiratory sensitisers and recommended several practical steps to...
27.03.2017 Read more
ECETOC Publications Catalogue

ECETOC Publications Catalogue

Catalogue of ECETOC Publications up to June 2018...
15.03.2017 Read more
Article

Behaviour of chemical respiratory allergens in novel predictive methods for skin sensitisation

02.03.2017 Read more
ECETOC 2016 Annual Report
Annual Report

ECETOC 2016 Annual Report

Overview of the 2016 activities and output of the European Centre for Ecotoxicology and Toxicology of Chemicals (ECETOC)...
20.02.2017 Read more

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