2025 Annual Report
Annual Report
January 2026 news from the Sec Gen
News

January 2026 news from the Sec Gen

Dear colleagues and friends, As we begin a new year, I would like to thank you for your continued engagement and trust in ECETOC. 2026 promises to be an exciting and dynamic year, and I am pleased...
ECETOC launches Secondee Programme
News

ECETOC launches Secondee Programme

Looking for an extra challenge? A next step to help develop your career? Consider applying for our Secondee Programme! ECETOC is looking for early-career scientists currently working at a member co...
HSSD Tool

HSSD Tool

This software was developed by a consortium of partners to facilitate the uptake of novel approaches to estimate aquatic threshold concentrations (e.g. the concentration at which 5% of the species are exposed above their EC50, HC5).
The Human Exposure Assessment Tools Database (heatDB)

The Human Exposure Assessment Tools Database (heatDB)

heatdb is a public directory of exposure data sources as well as available tools for exposure
NanoApp

NanoApp

ECETOC’s NanoApp is a tool designed to define the boundaries of sets of similar nanoforms and to generate a justification for the REACH registration.
Targeted Risk Assessment (TRA)

Targeted Risk Assessment (TRA)

The Targeted Risk Assessment (TRA) estimates exposures to workers, consumers and the environment that arise during a series of events.
Chronic fish case studies towards an IATA

Chronic fish case studies towards an IATA

Why? Hazard and safety assessments for the pelagic compartment often rely on in vivo studies using a single fish species, raising ethical concerns and uncertainty in terms of extrapolation....
Estimating the environmental release of Synthetic Polymeric Microparticles from Products

Estimating the environmental release of Synthetic Polymeric Microparticles from Products

Why? REACH restriction: SPM use restricted; emissions reporting required by May 2027. Gap: No analytical methods available to measure SPM emissions. Solution: Draft SPERC-based approac...
Case Studies on Reliability and Relevance Considerations during Validation of NAMs

Case Studies on Reliability and Relevance Considerations during Validation of NAMs

Why? Validation of NAMs is often overlooked despite its importance for regulatory use. Traditional validation methods are less suitable for NAMs, which focus on key events rather than apical...
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Publications

Technical Report

TR 029 – Concentrations of Industrial Organic Chemicals Measured in the Environment: The Influence of Physico-Chemical Properties, Tonnage and Use Pattern

TR 029 : Concentrations of Industrial Organic Chemicals Measured in the Environment: The Influence of Physico-Chemical Properties, Tonnage and Use Pattern | June 1988...
Technical Report

TR 028 – Evaluation of Anaerobic Biodegradation

TR 028 : Evaluation of Anaerobic Biodegradation | June 1988...
Monograph

Monograph 011 – Eye Irritation Testing

Mono 011 : Eye Irritation Testing | June 1988  ...
Article

Establishment of a test guideline for the evaluation of fish tainting

A Test Guideline has been established for determining the potential of a chemical to taint seafood. This Guideline, based on the exposure of fish and the evaluation of the imparted taint by a triangul...
Technical Report

TR 027 – Nitrate and Drinking Water

TR 027 : Nitrate and Drinking Water | January 1988...
Monograph

Monograph 010 – Identification of Immunotoxic Effects of Chemicals and Assessment of their Relevance to Man

Mono 010 : Identification of Immunotoxic Effects of Chemicals and Assessment of their Relevance to Man | August 1987...
Document

DOC 027 – ECETOC Statement: Current Results from European Chemical Industry-Sponsored Research into Species Differences in the Toxicology of Methylene Chloride

DOC 027 : ECETOC Statement: Current Results from European Chemical Industry-Sponsored Research into Species Differences in the Toxicology of Methylene Chloride | August 1987...
Monograph

Monograph 009 – Assessment of Mutagenicity of Industrial and Plant Protection Chemicals

Mono 009 : Assessment of Mutagenicity of Industrial and Plant Protection Chemicals | June 1987  ...
JACC

JACC Report 08 – Methyl Isobutyl Ketone

JACC 008 : Methyl Isobutyl Ketone | May 1987  ...
Technical Report

TR 026 – The Assessment of Carcinogenic Hazard for Human Beings exposed to Methylene Chloride

TR 026 : The Assessment of Carcinogenic Hazard for Human Beings exposed to Methylene Chloride | January 1987  ...
Technical Report

TR 025 – Evaluation of Fish Tainting

TR 025 : Evaluation of Fish Tainting | January 1987...
Technical Report

TR 024 – The EEC 6th Amendment: Prolonged Fish Toxicity Tests

TR 024 : The EEC 6th Amendment: Prolonged Fish Toxicity Tests | October 1986...
Technical Report

TR 023 – Evaluation of the Toxicity of Substances to be Assessed for Biodegradability

TR 023 : Evaluation of the Toxicity of Substances to be Assessed for Biodegradability | November 1986...
Technical Report

TR 022 – Classification of Dangerous Substances and Pesticides in the EEC Directives. A Proposed Revision of Criteria for Inhalational Toxicity

TR 022 : Classification of Dangerous Substances and Pesticides in the EEC Directives. A Proposed Revision of Criteria for Inhalational Toxicity | January 1987...
Document

DOC 026 – ECETOC Statement on Ethylene Oxide Toxicology and its Relevance to Man

DOC 026 : ECETOC Statement on Ethylene Oxide Toxicology and its Relevance to Man | October 1986...
JACC

JACC Report 07 – Ethylbenzene

JACC 027 : n-Butyl Acrylate (CAS No.141-32-2) | August 1994...
Document

DOC 025 – EPA Proposed Test Rule, Standards, for 1,1- Dichloroethylene under TSCA

DOC 025 : EPA Proposed Test Rule, Standards for 1,1-Dichloroethylene under TSCA | August 1986...
Monograph

Monograph 008 – Structure-Activity Relationships in Toxicology and Ecotoxicology: an Assessment (Summary)

Mono 008 : Structure-Activity Relationships in Toxicology and Ecotoxicology: an Assessment (Summary) | June 1986 Abstract A critical assessment of the scope, applicability and limitations of structur...
JACC

JACC Report 06 – Xylenes

JACC 006 : Xylenes | June 1986...
Document

DOC 024 – ECETOC Statement on US National Cancer Institute (NCI) Epidemiological Study on Formaldehyde

DOC 024 : ECETOC Statement on US National Cancer Institute (NCI) Epidemiological Study on Formaldehyde | March 1986...
Technical Report

TR 021 – Guide to the Classification of Carcinogens, Mutagens, and Teratogens under the 6th Amendment

TR 021 : Guide to the Classification of Carcinogens, Mutagens, and Teratogens under the 6th Amendment | February 1986...
Document

DOC 023 – ECETOC Summary Review: Recent Findings Relevant to Carcinogenicity of Formaldehyde

DOC 023 : ECETOC Summary Review: Recent Findings Relevant to the Carcinogenicity of Formaldehyde | February 1986  ...
Technical Report

TR 020 – Biodegradation Tests of Poorly-Soluble Compounds

TR 020 : Biodegradation Tests of Poorly-Soluble Compounds | February 1986...
Monograph

Monograph 007 – Recommendations for the Harmonisation of International Guidelines for Toxicity Studies

Mono 007 : Recommendations for the Harmonisation of International Guidelines for Toxicity Studies | December 1985...

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