2025 Annual Report
Annual Report
ECETOC publishes a framework for the risk assessment of plastic additives
Press Release

ECETOC publishes a framework for the risk assessment of plastic additives

Part 1 sets out the fundamental elements, from problem formulation to risk characterisation. Brussels, 22 July 2026. The ECETOC Plastic Additives Task Force has published the first of two peer...
January 2026 news from the Sec Gen
News

January 2026 news from the Sec Gen

Dear colleagues and friends, As we begin a new year, I would like to thank you for your continued engagement and trust in ECETOC. 2026 promises to be an exciting and dynamic year, and I am pleased...
HSSD Tool

HSSD Tool

This software was developed by a consortium of partners to facilitate the uptake of novel approaches to estimate aquatic threshold concentrations (e.g. the concentration at which 5% of the species are exposed above their EC50, HC5).
The Human Exposure Assessment Tools Database (heatDB)

The Human Exposure Assessment Tools Database (heatDB)

heatdb is a public directory of exposure data sources as well as available tools for exposure
NanoApp

NanoApp

ECETOC’s NanoApp is a tool designed to define the boundaries of sets of similar nanoforms and to generate a justification for the REACH registration.
Targeted Risk Assessment (TRA)

Targeted Risk Assessment (TRA)

The Targeted Risk Assessment (TRA) estimates exposures to workers, consumers and the environment that arise during a series of events.
Immunotoxicity assessment: Addressing Challenges and Advancing Methodologies [Workshop → Task Force]​

Immunotoxicity assessment: Addressing Challenges and Advancing Methodologies [Workshop → Task Force]​

Why? Regulatory assessment of immunotoxic properties of chemicals is a complex and challenging task​ Limited regulatory guidance exists​ Lack of industry and regulatory knowledge​...
Chronic fish case studies towards an IATA

Chronic fish case studies towards an IATA

Why? Hazard and safety assessments for the pelagic compartment often rely on in vivo studies using a single fish species, raising ethical concerns and uncertainty in terms of extrapolation....
Estimating the environmental release of Synthetic Polymeric Microparticles from Products

Estimating the environmental release of Synthetic Polymeric Microparticles from Products

Why? REACH restriction: SPM use restricted; emissions reporting required by May 2027. Gap: No analytical methods available to measure SPM emissions. Solution: Draft SPERC-based approac...
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Publications

Monograph

Monograph 007 – Recommendations for the Harmonisation of International Guidelines for Toxicity Studies

Mono 007 : Recommendations for the Harmonisation of International Guidelines for Toxicity Studies | December 1985...
JACC

JACC Report 05 – Vinylindene Chloride

JACC 005 : Vinylidene Chloride | August 1985...
Technical Report

TR 019 – An Assessment of Occurrence and Effects of Dialkyl-o-Phthalates in the Environement

TR 019 : An Assessment of Occurrence and Effects of Dialkyl-o-Phthalates in the Environement | May 1985...
Monograph

Monograph 006 – Acute Toxicity Tests, LD50 (LC50) Determinations and Alternatives

Mono 006 : Acute Toxicity Tests, LD50 (LC50) Determinations and Alternatives | May 1985...
Technical Report

TR 018 – Harmonisation of Ready Biodegradability Tests

TR 018 : Harmonisation of Ready Biodegradability Tests | April 1985...
Technical Report

TR 017 – The Toxicology of Glycol Ethers and its Relevance to Man: An Up-Dating of ECETOC Technical Report No. 4

TR 017 : The Toxicology of Glycol Ethers and its Relevance to Man: An Up-Dating of ECETOC Technical Report No. 4 | April 1984...
Technical Report

TR 016 – A Review of Recent Literature on the Toxicology of Benzene

TR 116 : Category approaches, read-across, (Q)SAR | 21 November 2012 Background An accepted practice for the assessment of human health and environmental safety of chemicals is the use of models...
Document

DOC 022 – EPA Proposed Guidelines for Carcinogen Risk Assessment

DOC 022 : EPA Proposed Guidelines for Carcinogen Risk Assesment | November 1984...
Document

DOC 021 – ECETOC Statement on Formaldhyde

DOC 021 : ECETOC Statement on Formaldehyde | November 1984...
Technical Report

TR 015 – The Use of Physical-Chemical Properties in the 6th Amendment and their Required Precision, Accuracy and Limiting Values

TR 015 : The Use of Physical-Chemical Properties in the 6th Amendment and their Required Precision, Accuracy and Limiting Values | June 1984...
Technical Report

TR 014 – The EEC 6th Amendment: A Guide to Risk Evaluation for Effects on Human Health

TR 014 : The EEC 6th Amendment: A Guide to Risk Evaluation for Effects on Human Health | March 1984...
Technical Report

TR 013 – The EEC 6th Amendment: A Guide to Risk Evaluation for Effects on the Environment

TR 013 : The EEC 6th Amendment: A Guide to Risk Evaluation for Effects on the Environment | March 1984  ...
Technical Report

TR 012 – The Phototransformation of Chemicals in Water: Results of a Ring-Test

TR 012 : The Phototransformation of Chemicals in Water: Results of a Ring-Test | June 1984...
Technical Report

TR 011 – Ethylene Oxide Toxicology and its Relevance to Man: An Up-Dating of ECETOC Technical Report No. 5

TR 011 : Ethylene Oxide Toxicology and its Relevance to Man: An Up-Dating of ECETOC Technical Report No. 5 | March 1984...
Technical Report

TR 010 – Considerations Regarding the Extrapolation of Biological Data in Deriving Occupational Exposure Limits

TR 010 : Considerations Regarding the Extrapolation of Biological Data in Deriving Occupational Exposure Limits | February 1984...
JACC

JACC Report 04 – Methylene Chloride

JACC 004 : Methylene Chloride | January 1984...
Technical Report

TR 009 – Assessment of Reverse-Phase Chromatographic Methods for Determining Partition Coefficients

TR 009 : Assessment of Reverse-Phase Chromatographic Methods for Determining Partition Coefficients | December 1983...
Monograph

Monograph 005 – Identification and Assessment of the Effects of Chemicals on Reproduction and Development (Reproductive Toxicology)

Mono 005 : Identification and Assessment of the Effects of Chemicals on Reproduction and Development (Reproductive Toxicology) | December 1983...
Technical Report

TR 008 – Biodegradation Testing: An Assessment of the Present Status

TR 008 : Biodegradation Testing: An Assessment of the Present Status | November 1983...
Technical Report

TR 007 – Experimental Assessment of the Phototransformation of Chemicals in the Atmosphere

TR 007 : Experimental Assessment of the Phototransformation of Chemicals in the Atmosphere | September 1983...
Document

DOC 019 – Environmental Risk Assessment Based on 6th Amendment Information

DOC 019 : Environment Risk Assessment based on 6th Amendment Information | June 1983...
JACC

JACC Report 03 – Methyl, Ethyl, Ketone

JACC 003 : Methyl Ethyl Ketone | February 1983...
JACC

JACC Report 02 – 1,4 Dioxane

JACC 002 : 1,4-Dioxane | February 1983...
JACC

JACC Report 01 – Melamine

JACC 001 : Melamine | February 1983...

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