2025 Annual Report
Annual Report
ECETOC publishes a framework for the risk assessment of plastic additives
Press Release

ECETOC publishes a framework for the risk assessment of plastic additives

Part 1 sets out the fundamental elements, from problem formulation to risk characterisation. Brussels, 22 July 2026. The ECETOC Plastic Additives Task Force has published the first of two peer...
January 2026 news from the Sec Gen
News

January 2026 news from the Sec Gen

Dear colleagues and friends, As we begin a new year, I would like to thank you for your continued engagement and trust in ECETOC. 2026 promises to be an exciting and dynamic year, and I am pleased...
HSSD Tool

HSSD Tool

This software was developed by a consortium of partners to facilitate the uptake of novel approaches to estimate aquatic threshold concentrations (e.g. the concentration at which 5% of the species are exposed above their EC50, HC5).
The Human Exposure Assessment Tools Database (heatDB)

The Human Exposure Assessment Tools Database (heatDB)

heatdb is a public directory of exposure data sources as well as available tools for exposure
NanoApp

NanoApp

ECETOC’s NanoApp is a tool designed to define the boundaries of sets of similar nanoforms and to generate a justification for the REACH registration.
Targeted Risk Assessment (TRA)

Targeted Risk Assessment (TRA)

The Targeted Risk Assessment (TRA) estimates exposures to workers, consumers and the environment that arise during a series of events.
Immunotoxicity assessment: Addressing Challenges and Advancing Methodologies [Workshop → Task Force]​

Immunotoxicity assessment: Addressing Challenges and Advancing Methodologies [Workshop → Task Force]​

Why? Regulatory assessment of immunotoxic properties of chemicals is a complex and challenging task​ Limited regulatory guidance exists​ Lack of industry and regulatory knowledge​...
Chronic fish case studies towards an IATA

Chronic fish case studies towards an IATA

Why? Hazard and safety assessments for the pelagic compartment often rely on in vivo studies using a single fish species, raising ethical concerns and uncertainty in terms of extrapolation....
Estimating the environmental release of Synthetic Polymeric Microparticles from Products

Estimating the environmental release of Synthetic Polymeric Microparticles from Products

Why? REACH restriction: SPM use restricted; emissions reporting required by May 2027. Gap: No analytical methods available to measure SPM emissions. Solution: Draft SPERC-based approac...
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Publications

Document

DOC 018 – Ecetoc Statement on Skin Sensitisation Testing and Labelling under 6th Amendment

DOC 018 : ECETOC Statement on Skin Sensitisation Testing and Labelling under 6th Amendment | November 1982...
Monograph

Monograph 004 – Hepatocarcinogenesis in Laboratory Rodents: Relevance for Man

Mono 004 : Hepatocarcinogenesis in Laboratory Rodents: Relevance for Man | October 1982...
Technical Report

TR 006 – Formaldehyde Toxicology: An Up-Dating of ECETOC Technical Reports 1 and 2

TR 006 : Formaldehyde Toxicology: An Up-Dating of ECETOC Technical Reports 1 and 2 | September 1982...
Technical Report

TR 005 – Toxicity of Ethylene Oxide and its Relevance to Man

TR 005 : Toxicity of Ethylene Oxide and its Relevance to Man | September 1982  ...
Document

DOC 017 – Comments to Bureau of Chemical Safety Health Protection Branch Health and Welfare Dept., Canada Reproduction Studies

DOC 017 : Comments to Bureau of Chemical Safety Health Protection Branch Health and Welfare Dept. Canada Reproduction Studies | September 1982...
Technical Report

TR 004 – The Toxicology of Ethylene Glycol Monoalkyl Ethers and its Relevance to Man

TR 004 : The Toxicology of Ethylene Glycol Monoalkyl Ethers and its Relevance to Man | June 1982...
Monograph

Monograph 003 – Risk Assessment of Occupational Chemical Carcinogens

Mono 003 : Risk Assessment of Occupational Chemical Carcinogens | January 1982...
Document

DOC 016 – ECETOC Colloquim Photodegradation

DOC 016 : ECETOC Colloquium Photodegradation | October 1981...
Technical Report

TR 003 – Assessment of Test Methods for Photodegradation of Chemicals in the Environment

TR 003 : Assessment of Test Methods for Photodegradation of Chemicals in the Environment | August 1981...
Technical Report

TR 002 – The Mutagenic and Carcinogenic Potential of Formaldehyde

TR 002 : The Mutagenic and Carcinogenic Potential of Formaldehyde | May 1981...
Document

DOC 015 – Summary of Results Presented at the CIIT Conference on Formaldehyde Toxicity on 20-21st November 1980

DOC 015 : Summary of Results Presented at the CIIT Conference on Formaldehyde Toxicity on 20-21 November 1980 | February 1981...
Document

DOC 014 – ECETOC Statement on Formaldehyde

DOC 014 : ECETOC Statement on Formaldehyde | February 1981...
Document

DOC 013 – The Organisation of Jointly-Sponsored (ECO) Toxicological Studies

DOC 013 : The Organisation of Jointly-Sponsored (Eco)Toxicological Studies| December 1980 ECETOC members sometimes participate in (eco) toxicological studies, jointly sponsored at a contract labora...
Document

DOC 012 – Criteria for Choosing Chemicals for Testing

DOC 012 : Criteria for Choosing Chemicals for Testing | December 1980...
Document

DOC 011 – Prolonged Toxicity Study with Daphnia Magna

DOC 011 : Prolonged Toxicity Study with Daphnia Magna | November 1980...
Document

DOC 010 – Skin Sensitisation

DOC 010 : Skin Sensitisation | October 1980 The task force report gives a state of the science on animal tests for skin contact sensitisation; it discusses the correlation between animal and human...
Document

DOC 009 – Test Method for Acute Toxicity to Daphna Magna

DOC 009 : Test Method for Acute Toxicity to Daphnia Magna | October 1980...
Document

DOC 006 – Relevance to Model Experiments to Photodegradation in The Environment

DOC 006 : Relevance to Model Experiments to Photodegredation in the Environment | October 1980 An ECETOC task force has reviewed the state of the art in photodegradation and is defining what work n...
Document

DOC 007-8 : Methodology of Biotic and Abiotic Testing in 6th Amendment | October 1980

DOC 007-8 : Methodology of Biotic and Abiotic Testing in 6th Amendment...
Monograph

Monograph 002 – A Contribution to Strategy for Identification and Control of Occupational Carcinogens

Mono 002 : A Contribution to Strategy for Identification and Control of Occupational Carcinogens | September 1980...
Document

DOC 005 – Teratogenicity – Definition

DOC 005 : Teratogenicity - Definition | June 1980 ECETOC established a task force ?Teratogenicity? which was asked to define a chemical teratogen in terms which are scientifically correct and which...
Document

DOC 004 – Non Clinical Laboratory Studies : Amendment of Good Laboratory Practice Regulations

DOC 004 : Non-Clinical Laboratory Studies: Amendment of Good Laboratory Practice Regulations | December 1979 Written comments from ECETOC on the Food and Drug Administration?s proposed Amendment of...
Monograph

Monograph 001 – Good Laboratory Practice

Mono 001 : Good Laboratory Practice | October 1979...
Document

DOC 003 – Proposed Health Effects Test Standards for Toxic Substances Control ACT Test Rules

DOC 003 : Proposed Health Effects Test Standards for Toxic Substances Control ACT Test Rules | October 1979 The EPA on page 27334, column 1 states that the ultimate purpose of the stanards under co...

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