2025 Annual Report
Annual Report

2025 Annual Report

06.05.2026 read more
Building trust in the integration of artificial intelligence into chemical risk assessment: findings from the 2024 ECETOC workshop
ArticleWorkshop Report

Building trust in the integration of artificial intelligence into chemical risk assessment: findings from the 2024 ECETOC workshop

23.03.2026 read more
From concept to application: Repeat dose toxicity testing workshop
07.05.2026 - 08.05.2026

From concept to application: Repeat dose toxicity testing workshop

Read more
Planetary boundary for novel entities
06.05.2026 - 07.05.2026

Planetary boundary for novel entities

Read more
January 2026 news from the Sec Gen
News

January 2026 news from the Sec Gen

Dear colleagues and friends, As we begin a new year, I would like to thank you for your continued engagement and trust in ECETOC. 2026 promises to be an exciting and dynamic year, and I am pleased...
29.01.2026 Read more
ECETOC launches Secondee Programme
News

ECETOC launches Secondee Programme

Looking for an extra challenge? A next step to help develop your career? Consider applying for our Secondee Programme! ECETOC is looking for early-career scientists currently working at a member co...
13.11.2025 Read more
Epigenetics – Roland Buesen
01.06.2016

Epigenetics – Roland Buesen

See the video
HSSD Tool

HSSD Tool

This software was developed by a consortium of partners to facilitate the uptake of novel approaches to estimate aquatic threshold concentrations (e.g. the concentration at which 5% of the species are exposed above their EC50, HC5).
03.10.2025 Read more
The Human Exposure Assessment Tools Database (heatDB)

The Human Exposure Assessment Tools Database (heatDB)

heatdb is a public directory of exposure data sources as well as available tools for exposure
03.10.2025 Read more
NanoApp

NanoApp

ECETOC’s NanoApp is a tool designed to define the boundaries of sets of similar nanoforms and to generate a justification for the REACH registration.
03.10.2025 Read more
Targeted Risk Assessment (TRA)

Targeted Risk Assessment (TRA)

The Targeted Risk Assessment (TRA) estimates exposures to workers, consumers and the environment that arise during a series of events.
03.10.2025 Read more
Chronic fish case studies towards an IATA

Chronic fish case studies towards an IATA

Why? Hazard and safety assessments for the pelagic compartment often rely on in vivo studies using a single fish species, raising ethical concerns and uncertainty in terms of extrapolation....
24.02.2026 Read more
Estimating the environmental release of Synthetic Polymeric Microparticles from Products

Estimating the environmental release of Synthetic Polymeric Microparticles from Products

Why? REACH restriction: SPM use restricted; emissions reporting required by May 2027. Gap: No analytical methods available to measure SPM emissions. Solution: Draft SPERC-based approac...
24.02.2026 Read more
Case Studies on Reliability and Relevance Considerations during Validation of NAMs

Case Studies on Reliability and Relevance Considerations during Validation of NAMs

Why? Validation of NAMs is often overlooked despite its importance for regulatory use. Traditional validation methods are less suitable for NAMs, which focus on key events rather than apical...
07.07.2025 Read more
a

Publications
2025 Annual Report
Annual Report

2025 Annual Report

06.05.2026 Read more
Building trust in the integration of artificial intelligence into chemical risk assessment: findings from the 2024 ECETOC workshop
ArticleWorkshop Report

Building trust in the integration of artificial intelligence into chemical risk assessment: findings from the 2024 ECETOC workshop

23.03.2026 Read more
A quantitative definition for poorly soluble particles
Article

A quantitative definition for poorly soluble particles

18.03.2026 Read more
Workshop Flash Report – Immunotoxicity assessment: Addressing challenges and advancing methodologies
Workshop Report

Workshop Flash Report – Immunotoxicity assessment: Addressing challenges and advancing methodologies

03.03.2026 Read more
Framework for classifying chemicals for repeat dose toxicity using NAMs
Article

Framework for classifying chemicals for repeat dose toxicity using NAMs

18.08.2025 Read more
2024 Annual Report
Annual Report

2024 Annual Report

05.06.2025 Read more
Workshop Report no.41- Overcoming challenges and advancing (bio)degradation guidelines: OECD TG309 revisited
Workshop Report

Workshop Report no.41- Overcoming challenges and advancing (bio)degradation guidelines: OECD TG309 revisited

In a Nutshell The OECD Test Guideline (TG) 309, designed to assess the degradation of chemicals in aerobic surface water, has become increasingly important in regulatory frameworks, especially within...
16.05.2025 Read more
Integrating AI into chemical safety assessment – Flash Report
Workshop Report

Integrating AI into chemical safety assessment – Flash Report

29.01.2025 Read more
Testing, Assessment and Classification of Thyroid Hormone Disruptors – Flash Report
Workshop Report

Testing, Assessment and Classification of Thyroid Hormone Disruptors – Flash Report

23.01.2025 Read more
Use and limitations of clinical data in the identification and classification of low molecular weight chemicals (LMWCs) as respiratory sensitizers: recommendations for improvement
Article

Use and limitations of clinical data in the identification and classification of low molecular weight chemicals (LMWCs) as respiratory sensitizers: recommendations for improvement

22.01.2025 Read more
REACH assessment of humans exposed to chemicals indirectly via the environment: screening modeling in EUSES versus state of the science
Article

REACH assessment of humans exposed to chemicals indirectly via the environment: screening modeling in EUSES versus state of the science

06.01.2025 Read more
Integrating population-level effects into the regulatory assessment of endocrine disrupting substances
Article

Integrating population-level effects into the regulatory assessment of endocrine disrupting substances

06.01.2025 Read more
A unified approach to SimpleTreat input and settings for wastewater treatment removal predictions
Article

A unified approach to SimpleTreat input and settings for wastewater treatment removal predictions

06.01.2025 Read more
Workshop Report no.40 – Chronos and Kairos: Understanding time in biology for NGRA
Workshop Report

Workshop Report no.40 – Chronos and Kairos: Understanding time in biology for NGRA

09.10.2024 Read more
Workshop Report no.39 – Elevating exposure science in CSA: Developing recommendations for stakeholders
Workshop Report

Workshop Report no.39 – Elevating exposure science in CSA: Developing recommendations for stakeholders

02.07.2024 Read more
Practical considerations to optimize aquatic testing of particulate material, with focus on nanomaterials
Article

Practical considerations to optimize aquatic testing of particulate material, with focus on nanomaterials

01.07.2024 Read more
2023 Annual Report
Annual Report

2023 Annual Report

23.05.2024 Read more
Considerations for the development of guidance on dose level selection for developmental and reproductive toxicity studies
Article

Considerations for the development of guidance on dose level selection for developmental and reproductive toxicity studies

04.03.2024 Read more
Workshop Report no.38 – Exploring best practices in quantitative AOPs (qAOPs)
Workshop Report

Workshop Report no.38 – Exploring best practices in quantitative AOPs (qAOPs)

08.02.2024 Read more
TR 142 – Approaching cross-sector aggregate substance exposure assessment for consumers
Technical Report

TR 142 – Approaching cross-sector aggregate substance exposure assessment for consumers

11.12.2023 Read more
Three-tiered approach for standard information requirements for polymers requiring registration under REACH
Article

Three-tiered approach for standard information requirements for polymers requiring registration under REACH

08.11.2023 Read more
Analysis of health concerns not addressed by REACH for low tonnage chemicals and opportunities for new approach methodology
Article

Analysis of health concerns not addressed by REACH for low tonnage chemicals and opportunities for new approach methodology

19.10.2023 Read more
TR 141 – Comparison of measured and modelled short-term inhalation and dermal exposure
Technical Report

TR 141 – Comparison of measured and modelled short-term inhalation and dermal exposure

04.10.2023 Read more
Towards a science-based testing strategy to identify maternal thyroid hormone imbalance and neurodevelopmental effects in the progeny – Part IV: the ECETOC and CLE Proposal for a Thyroid Function-Related Neurodevelopmental Toxicity Testing and Assessment Scheme (Thyroid-NDT-TAS)
Article

Towards a science-based testing strategy to identify maternal thyroid hormone imbalance and neurodevelopmental effects in the progeny – Part IV: the ECETOC and CLE Proposal for a Thyroid Function-Related Neurodevelopmental Toxicity Testing and Assessment Scheme (Thyroid-NDT-TAS)

10.08.2023 Read more

Don’t miss an event

Always stay in the loop by signing up to the ECETOC Newsletter

Sign up