ECETOC Publication Highlights Scientific Perspectives on Developmental Neurotoxicity Testing and Future Regulatory Directions
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ECETOC Publication Highlights Scientific Perspectives on Developmental Neurotoxicity Testing and Future Regulatory Directions

Brussels, 1 October 2026 – ECETOC is pleased to announce the publication of a new review article in Archives of Toxicology titled “Scientific Perspectives on In Vivo Developmental Neurotoxicity T...
Welcome to Talia Neal-Walthall
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Welcome to Talia Neal-Walthall

We are pleased to welcome Talia Neal-Walthall to ECETOC as a secondee. Talia joins us to work on topics related to exposure, an area central to much of our current scientific programme. She will be wi...
HSSD Tool

HSSD Tool

This software was developed by a consortium of partners to facilitate the uptake of novel approaches to estimate aquatic threshold concentrations (e.g. the concentration at which 5% of the species are exposed above their EC50, HC5).
The Human Exposure Assessment Tools Database (heatDB)

The Human Exposure Assessment Tools Database (heatDB)

heatdb is a public directory of exposure data sources as well as available tools for exposure
NanoApp

NanoApp

ECETOC’s NanoApp is a tool designed to define the boundaries of sets of similar nanoforms and to generate a justification for the REACH registration.
Targeted Risk Assessment (TRA)

Targeted Risk Assessment (TRA)

The Targeted Risk Assessment (TRA) estimates exposures to workers, consumers and the environment that arise during a series of events.
TRA Task Force – Worker branch

TRA Task Force – Worker branch

Why? The Worker TRA Task Force has been active since 2019, delivering projects that advance the scientific basis of the Worker Targeted Risk Assessment (TRA) tool. Its overarching objective is to e...
Immunotoxicity assessment: Addressing Challenges and Advancing Methodologies [Workshop → Task Force]​

Immunotoxicity assessment: Addressing Challenges and Advancing Methodologies [Workshop → Task Force]​

Why? Regulatory assessment of immunotoxic properties of chemicals is a complex and challenging task​ Limited regulatory guidance exists​ Lack of industry and regulatory knowledge​...
Chronic fish case studies towards an IATA

Chronic fish case studies towards an IATA

Why? Hazard and safety assessments for the pelagic compartment often rely on in vivo studies using a single fish species, raising ethical concerns and uncertainty in terms of extrapolation....
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Publications

Workshop Report

Workshop Report 10 – Workshop on Biodegradation and Persistence.

WR 10 : Workshop on Biodegradation and Persistence. | September 2007 This two-day workshop sponsored and organised by ECETOC and co-sponsored by the Environment Agency for England and Wales, took p...
JACC

JACC Report 53 – Cyanides of Hydrogen, Sodium and Potassium, and Acetone Cyanohydrin vol.II

JACC 053 Vol II : Cyanides of Hydrogen, Sodium and Potassium, and Acetone Cyanohydrin (CAS No. 74-90-8, 143-33-9, 151-50-8 and 75-86-5), Volumes I and II | November 2007 This report has been produc...
JACC

JACC Report 53 – Cyanides of Hydrogen, Sodium and Potassium, and Acetone Cyanohydrin vol.I

JACC 053 Vol I : Cyanides of Hydrogen, Sodium and Potassium, and Acetone Cyanohydrin (CAS No. 74-90-8, 143-33-9, 151-50-8 and 75-86-5), Volumes I and II | November 2007 This report has been produce...
Monograph

Monograph 037 – Biomarkers in Children and Adults

Mono 037 : Biomarkers in Children and Adults | 30 July 2007...
Article

The ECETOC approach to targeted risk assessment, lessons and experiences relevant to REACH

ECETOC has been developed an approach by which the health and environmental risks arising from the supply and use of chemicals can be quickly and reliably evaluated by chemical suppliers. The approach...
Technical Report

TR 101 – Guidance for setting occupational exposure limits: Emphasis on data-poor substances

TR 101 : Guidance for setting occupational exposure limits: Emphasis on data-poor substances | October 2006 In the absence of sound human exposure data, existing procedures for setting occupational e...
Workshop Report

Workshop Report 08 – Workshop on societal aspects of nanotechnology

WR 08 : Workshop on societal aspects of nanotechnology | October 2006 Increasingly, public perception and acceptance are key factors in the introduction and development of new technologies. The quest...
JACC

JACC Report 52 – Trifluoroethane (HFC-143a)

JACC 052 : Trifluoroethane | October 2006 This report has been produced as part of the ECETOC Joint Assessment of Commodity Chemicals (JACC) programme. It presents a critical evaluation of the avai...
Annual Report
Workshop Report

Workshop Report 07 – Workshop on Testing Strategies to Establish the Safety of Nanomaterials

WR 07 : Workshop on Testing Strategies to Establish the Safety of Nanomaterials | September 2006 Nanotechnology produces an increasing number of engineered nanoparticles. A better understanding of...
Monograph

Monograph 036 – Environmental Genotoxins in Children and Adults

Mono 036 : Environmental Genotoxins in Children and Adults | 28 September 2006...
JACC

JACC Report 51 – Synthetic Amorphous Silica

JACC 051 : Synthetic Amorphous Silica | September 2006 This report has been produced as part of the ECETOC Joint Assessment of Commodity Chemicals (JACC) programme. It presents a critical evaluatio...
Monograph

Monograph 035 – Biomarkers and Molecular Epidemiology

Mono 035 : Biomarkers and Molecular Epidemiology | 31 August 2006...
Article

The potential risks of nanomaterials: a review carried out for ECETOC

During the last few years, research on toxicologically relevant properties of engineered nanoparticles has increased tremendously. A number of international research projects and additional activities...
Technical Report

TR 100 – Contribution to the Methodology for the Development of Acute Exposure Threshold Levels in Case of Accidental Chemical Release

TR 100 : Contribution to the Methodology for the Development of Acute Exposure Threshold Levels in Case of Accidental Chemical Release | July 2006 The ACUTEX project was a three-year research activit...
Technical Report

TR 099 – Toxicological Modes of Action: Relevance for Human Risk Assessment

TR 099 : Toxicological Modes of Action: Relevance for Human Risk Assessment | July 2006 Generally, the assessment of hazard and risk to humans that might arise from exposure to chemical substances is...
Workshop Report

Workshop Report 06 – Workshop on Chemical Pollution, Respiratory Allergy and Asthma

WR 06 : Workshop on Chemical Pollution, Respiratory Allergy and Asthma | February 2006 Atopic allergy and asthma remain important health issues. It is therefore of significance that in more moderni...
Technical Report

TR 098 – Risk Assessment of PBT Chemicals

TR 098 : Risk Assessment of PBT Chemicals | December 2005 Many chemical regulatory schemes exist around the world that contain hazard-based criteria to identify and prioritise persistent, bioaccumula...
Technical Report

TR 097 – Alternative Testing Approaches in Environmental Safety Assessment

TR 097 : Alternative Testing Approaches in Environmental Safety Assessment | January 2006 There are many opportunities for applying the principles of the three Rs (replacement, reduction and refineme...
JACC

JACC Report 50 – 1,1,1,2-Tetrafluoroethane (HFC-134a) Second edition

JACC 050 : 1,1,1,2-Tetrafluoroethane (HFC-134a) (CAS No. 811-97-2) (Second Edition) | January 2006 This report has been produced as part of the ECETOC Joint Assessment of Commodity Chemicals (JACC)...
JACC

JACC 049a : Corrigendum to JACC 49

Following publication of the above mentioned report, some errors have been brought to our attention. Please note that the corrections of the printed and PDF versions of the JACC Report No. 49 are as f...
JACC

JACC Report 49 – Vinylidene Fluoride

JACC 049 : Vinylidene Fluoride (CAS No. 75-38-7) | November 2005 This report has been produced as part of the ECETOC Joint Assessment of Commodity Chemicals (JACC) programme. It presents a critical...
Document

DOC 044 – Guidance for the Interpretation of Biomonitoring Data

DOC 044 : Guidance for the Interpretation of Biomonitoring Data | November 2005 Measuring the levels of chemical substances in human body fluids and tissues has been in routine use in industry and...

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