2025 Annual Report
Annual Report
ECETOC publishes a framework for the risk assessment of plastic additives
Press Release

ECETOC publishes a framework for the risk assessment of plastic additives

Part 1 sets out the fundamental elements, from problem formulation to risk characterisation. Brussels, 22 July 2026. The ECETOC Plastic Additives Task Force has published the first of two peer...
January 2026 news from the Sec Gen
News

January 2026 news from the Sec Gen

Dear colleagues and friends, As we begin a new year, I would like to thank you for your continued engagement and trust in ECETOC. 2026 promises to be an exciting and dynamic year, and I am pleased...
HSSD Tool

HSSD Tool

This software was developed by a consortium of partners to facilitate the uptake of novel approaches to estimate aquatic threshold concentrations (e.g. the concentration at which 5% of the species are exposed above their EC50, HC5).
The Human Exposure Assessment Tools Database (heatDB)

The Human Exposure Assessment Tools Database (heatDB)

heatdb is a public directory of exposure data sources as well as available tools for exposure
NanoApp

NanoApp

ECETOC’s NanoApp is a tool designed to define the boundaries of sets of similar nanoforms and to generate a justification for the REACH registration.
Targeted Risk Assessment (TRA)

Targeted Risk Assessment (TRA)

The Targeted Risk Assessment (TRA) estimates exposures to workers, consumers and the environment that arise during a series of events.
Immunotoxicity assessment: Addressing Challenges and Advancing Methodologies [Workshop → Task Force]​

Immunotoxicity assessment: Addressing Challenges and Advancing Methodologies [Workshop → Task Force]​

Why? Regulatory assessment of immunotoxic properties of chemicals is a complex and challenging task​ Limited regulatory guidance exists​ Lack of industry and regulatory knowledge​...
Chronic fish case studies towards an IATA

Chronic fish case studies towards an IATA

Why? Hazard and safety assessments for the pelagic compartment often rely on in vivo studies using a single fish species, raising ethical concerns and uncertainty in terms of extrapolation....
Estimating the environmental release of Synthetic Polymeric Microparticles from Products

Estimating the environmental release of Synthetic Polymeric Microparticles from Products

Why? REACH restriction: SPM use restricted; emissions reporting required by May 2027. Gap: No analytical methods available to measure SPM emissions. Solution: Draft SPERC-based approac...
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Publications

1999 Annual Report
Annual Report
Technical Report

TR 077 – Skin and Respiratory Sensitisers: Reference Chemical Data Bank

TR 077 : Skin and Respiratory Sensitisers: Reference Chemical Data Bank | August 1999 Certain chemicals can cause occupational and consumer health problems, such as allergic contact dermatitis and al...
JACC

JACC Report 38 – Monochloroacetic Acid and its Sodium Salt

JACC 038 : Monochloroacetic Acid (CAS No.79-11-8) and its Sodium Salt (CAS No.3926-62-3) | June 1999...
Special Report

Special Report 16 – GREAT-ER User Manual

SR 16 : GREAT-ER User Manual | March 1999...
Technical Report

TR 076 – Monitoring and Modelling of Industrial Organic Chemicals, with Particular Reference to Aquatic Risk Assessment

TR 076 : Monitoring and Modelling of Industrial Organic Chemicals, with Particular Reference to Aquatic Risk Assessment | January 1999 The process for establishing the environmental acceptability of...
Document

DOC 039 – Screening and Testing Methods for Ecotoxological Effects of Potential Endocrine Disrupters : Response to the EDSTAC Recommendations and a Propose Alternative Approach

DOC 039 : Screening and Testing Methods for Ecotoxicological Effects of Potential Endocrine Disrupters: Response to the EDSTAC. Recommendations and a Proposed Alternative Approach | January 1999...
Technical Report

TR 075 – Organophosphorus Pesticides and Long-term Effects on the Nervous System

TR 075 : Organophosphorus Pesticides and Long-term Effects on the Nervous System | December 1998 Organophosphorus pesticides (OPps) have been used for decades. In view of their potent biological effe...
Annual Report
Special Report

Special Report 15 – Examination of a proposed skin notation strategy

SR 15 : Examination of a Proposed Skin Notation Strategy | September 1998...
JACC

JACC Report 37 – Methyl Acrylate

JACC 037 : Methyl Acrylate (CAS No.96-33-3) | September 1998 This report presents a critical evaluation of the toxicology and ecotoxicology of methyl acrylate (CAS No.96-33-3). It has been produced...
Technical Report

TR 074 – QSARs in the Assessment of the Environmental Fate and Effects of Chemicals

TR 074 : QSARs in the Assessment of the Environmental Fate and Effects of Chemicals | June 1998 Quantitative Structure Activity Relationships (QSARs) are based on a comparison of the structure of som...
Special Report

Special Report 14 – n-Butyl Methacrylate Isobutyl Methacrylate OEL Criteria Document

SR 14 : n-Butyl Methacrylate and Isobutyl Methacrylate OEL Criteria Document | May 1998...
Article

Aneuploidy: A report of an ECETOC task force

Aneuploidy plays a significant role in adverse human health conditions including birth defects, pregnancy wastage and cancer. Although there is clear evidence of chemically induced aneuploidy in exper...
Document

DOC 038 – Wildlife and Endocrine Disrupters: Requirements for hazard Identification

DOC 038: Wildlife and Endocrine Disrupters: Requirements for hazard Identification...
Article

Analysis of the ECETOC aquatic toxicity (EAT) database II. Comparison of acute to chronic ratios for various aquatic organisms and chemical substances

Environmental risk assessment often requires prediction of potential chronic effects in aquatic species from acute toxicity data. The scientific rationale for using extrapolation factors for this con...
Article

Analysis of the ECETOC aquatic toxicity (EAT) database I. General Introduction

In assessing the environmental risk of a chemical it is necessary to predict safe levels in the environment, but this requires extrapolation from relatively small databases. To improve understanding...

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