2025 Annual Report
Annual Report
ECETOC publishes a framework for the risk assessment of plastic additives
Press Release

ECETOC publishes a framework for the risk assessment of plastic additives

Part 1 sets out the fundamental elements, from problem formulation to risk characterisation. Brussels, 22 July 2026. The ECETOC Plastic Additives Task Force has published the first of two peer...
January 2026 news from the Sec Gen
News

January 2026 news from the Sec Gen

Dear colleagues and friends, As we begin a new year, I would like to thank you for your continued engagement and trust in ECETOC. 2026 promises to be an exciting and dynamic year, and I am pleased...
HSSD Tool

HSSD Tool

This software was developed by a consortium of partners to facilitate the uptake of novel approaches to estimate aquatic threshold concentrations (e.g. the concentration at which 5% of the species are exposed above their EC50, HC5).
The Human Exposure Assessment Tools Database (heatDB)

The Human Exposure Assessment Tools Database (heatDB)

heatdb is a public directory of exposure data sources as well as available tools for exposure
NanoApp

NanoApp

ECETOC’s NanoApp is a tool designed to define the boundaries of sets of similar nanoforms and to generate a justification for the REACH registration.
Targeted Risk Assessment (TRA)

Targeted Risk Assessment (TRA)

The Targeted Risk Assessment (TRA) estimates exposures to workers, consumers and the environment that arise during a series of events.
Immunotoxicity assessment: Addressing Challenges and Advancing Methodologies [Workshop → Task Force]​

Immunotoxicity assessment: Addressing Challenges and Advancing Methodologies [Workshop → Task Force]​

Why? Regulatory assessment of immunotoxic properties of chemicals is a complex and challenging task​ Limited regulatory guidance exists​ Lack of industry and regulatory knowledge​...
Chronic fish case studies towards an IATA

Chronic fish case studies towards an IATA

Why? Hazard and safety assessments for the pelagic compartment often rely on in vivo studies using a single fish species, raising ethical concerns and uncertainty in terms of extrapolation....
Estimating the environmental release of Synthetic Polymeric Microparticles from Products

Estimating the environmental release of Synthetic Polymeric Microparticles from Products

Why? REACH restriction: SPM use restricted; emissions reporting required by May 2027. Gap: No analytical methods available to measure SPM emissions. Solution: Draft SPERC-based approac...
a

Publications

Technical Report

TR 050 – Estimating Environmental Concentrations of Chemicals Using Fate and Exposure Models

TR 050 : Estimating Environmental Concentrations of Chemicals Using Fate and Exposure Models | November 1992...
Technical Report

TR 049 – Exposure of Man to Dioxins: A Perspective on Industrial Waste Incineration

TR 049 : Exposure of Man to Dioxins: A Perspective on Industrial Waste Incineration | December 1992  ...
Special Report
Special Report

Special Report 03 – Studies on Toxicokinetics Macromolecular Binding of Styrene vol.1

SR 03 Vol I : Studies on Toxicokinetics and Macromolecular Binding of Styrene (Vols 1 and 2) | December 1992  ...
Monograph

Monograph 018 – Evaluation of the Neurotoxic Potential of Chemicals

Mono 018 : Evaluation of the Neurotoxic Potential of Chemicals | September 1992  ...
Technical Report

TR 047 – EC 7th Amendment “Toxic to Reproduction”: Guidance on Classification

TR 047 : EC 7th Amendment "Toxic to Reproduction": Guidance on Classification | August 1992...
Technical Report

TR 048 – Eye Irritation: Reference Chemicals Data Bank (Second Edition)

TR 048 : Eye Irritation: Reference Chemicals Data Bank (Second Edition) | June 1998...
Technical Report

TR 048a – Corrigendum to TR 48: Eye Irritation: Reference Chemicals Data Bank (Second Edition)

TR 048a : Corrigendum to TR 48: Eye Irritation: Reference Chemicals Data Bank (Second Edition) | February 2011...
Document

DOC 030 – Comments and Proposed Changes to OECD Screenings Information Data Set Draft Test Guidelines “Preliminary reproduction Toxicity Sreening Test” and “Combined Repead Dose and Reproductive / Developmental Toxicity Screen Test”

DOC 030 : Comments and Proposed Changes to OECD Screenings Information Data Set Draft Guidelines | July 1992 In the OECD Existing Chemicals Programme a Screening Information Data Set (SIDS) has bee...
Technical Report

TR 046 – EC 7th Amendment: Role of Mammalian Toxicokinetic and Metabolic Studies in the Toxicological Assessment of Industrial Chemicals

TR 046 : EC 7th Amendment: Role of Mammalian Toxicokinetic and Metabolic Studies in the Toxicological Assessment of Industrial Chemicals | May 1992...
Technical Report

TR 045 – Nickel, Cobalt and Chromium in Consumer Products: Allergic Contact Dermatitis

TR 045 : Nickel, Cobalt and Chromium in Consumer Products: Allergic Contact Dermatitis | March 1992...
Monograph

Monograph 017 – Hepatic Peroxisome Proliferation

Mono 017 : Hepatic Peroxisome Proliferation | May 1992...
JACC
Technical Report

TR 044 – Biodegradation Kinetics

TR 044 : Biodegradation Kinetics | September 1991...
Technical Report

TR 043 – Emergency Exposure Indices for Industrial Chemicals

TR 043 : Emergency Exposure Indices for Industrial Chemicals | March 1991...
Technical Report

TR 042 – Critical Evaluation of Methods for the Determination of N-Nitrosamines in Personal Care and Household Products

TR 042 : Critical Evaluation of Methods for the Determination of N-Nitrosamines in Personal Care and Household Products | August 1991...
Technical Report

TR 040(R) – Hazard Assessment of Chemical Contaminants (Revised Appendix 3)

TR 040(R) : Hazard Assessment of Chemical Contaminants (Revised Appendix 3) | April 1992...
Technical Report

TR 040 – Hazard Assessment of Chemical Contaminants in Soil

TR 040 : Hazard Assessment of Chemical Contaminants in Soil | April 1992...
Document

DOC 029 – Proposal for the Updating of OECD Test Guideline No 407

DOC 029 : Proposal for the Updating of OED Test Guideline No. 407 | August 1991...
JACC

JACC Report 19 – Dicyclopentadiene

JACC 019 : Dicyclopentadiene (CAS:77-73-6) | July 1991...
Special Report

Special Report 02 – Existing Chemicals Recommendations for Priority Setting

SR 02 : Existing Chemicals Recommendations for Priority Setting | June 1991...
Article

Skin sensitisation: A critical review of predictive test methods in animals and man

With the exception of the Draize Test, the guinea-pig test methods currently accepted by regulatory authorities worldwide are well able to predict the potential of a material to cause skin sensitiza...
Special Report

Special Report 01 – Existing Chemicals Guidance for Completing the EEC Data Set

SR 01 : Existing Chemicals Guidance for Completing the EEC Data Set | March 1991  ...
JACC

JACC Report 18 – Vinyl Acetate

JACC 018 : Vinyl Acetate | February 1991...

Don’t miss an event

Always stay in the loop by signing up to the ECETOC Newsletter