2025 Annual Report
Annual Report
ECETOC publishes a framework for the risk assessment of plastic additives
Press Release

ECETOC publishes a framework for the risk assessment of plastic additives

Part 1 sets out the fundamental elements, from problem formulation to risk characterisation.Brussels, 22 July 2026. The ECETOC Plastic Additives Task Force has published the first of two peer...
January 2026 news from the Sec Gen
News

January 2026 news from the Sec Gen

Dear colleagues and friends,As we begin a new year, I would like to thank you for your continued engagement and trust in ECETOC. 2026 promises to be an exciting and dynamic year, and I am pleased...
HSSD Tool

HSSD Tool

This software was developed by a consortium of partners to facilitate the uptake of novel approaches to estimate aquatic threshold concentrations (e.g. the concentration at which 5% of the species are exposed above their EC50, HC5).
The Human Exposure Assessment Tools Database (heatDB)

The Human Exposure Assessment Tools Database (heatDB)

heatdb is a public directory of exposure data sources as well as available tools for exposure
NanoApp

NanoApp

ECETOC’s NanoApp is a tool designed to define the boundaries of sets of similar nanoforms and to generate a justification for the REACH registration.
Targeted Risk Assessment (TRA)

Targeted Risk Assessment (TRA)

The Targeted Risk Assessment (TRA) estimates exposures to workers, consumers and the environment that arise during a series of events.
Chronic fish case studies towards an IATA

Chronic fish case studies towards an IATA

Why?Hazard and safety assessments for the pelagic compartment often rely on in vivo studies using a single fish species, raising ethical concerns and uncertainty in terms of extrapolation....
Estimating the environmental release of Synthetic Polymeric Microparticles from Products

Estimating the environmental release of Synthetic Polymeric Microparticles from Products

Why?REACH restriction: SPM use restricted; emissions reporting required by May 2027. Gap: No analytical methods available to measure SPM emissions. Solution: Draft SPERC-based approac...
Case Studies on Reliability and Relevance Considerations during Validation of NAMs

Case Studies on Reliability and Relevance Considerations during Validation of NAMs

Why?Validation of NAMs is often overlooked despite its importance for regulatory use. Traditional validation methods are less suitable for NAMs, which focus on key events rather than apical...
Technical Report
29.01.1999

TR 076 – Monitoring and Modelling of Industrial Organic Chemicals, with Particular Reference to Aquatic Risk Assessment

TR 076 : Monitoring and Modelling of Industrial Organic Chemicals, with Particular Reference to Aquatic Risk Assessment | January 1999

The process for establishing the environmental acceptability of a chemical substance involves evaluating the likelihood that an adverse ecological effect may occur as a consequence of its use. This judgement is based upon a knowledge of the inherent ability of the chemical to cause adverse effect and the concentration of the chemical in the environment. The concentration of a chemical can be estimated, using models, from the amount of the chemical released during its production, formulation, use and disposal. The most accepted way to confirm or refute these predictions is to measure the concentration in a monitoring study.

This report gives the following recommendations:
- how to plan, manage and audit cost-effective monitoring programmes;
- how to ensure that the data collected are representative for a given scenario;
- how to establish which existing data are of sufficiently high quality to preclude the need for further studies;
- how to optimise best the interplay between models and monitoring data. The report also studies the opportunities that exist to reduce the cost of field monitoring and makes recommendations for the harmonisation of existing and future monitoring programmes.