Scientific Perspectives on In Vivo Developmental Neurotoxicity Testing: Study Design, Regulatory Context, and Future Directions

ECETOC is pleased to share a newly published review: “Scientific Perspectives on In Vivo Developmental Neurotoxicity Testing: Study Design, Regulatory Context, and Future Directions.”

The paper provides a comprehensive overview of current approaches to developmental neurotoxicity (DNT) assessment, examining scientific considerations, regulatory applications, and future directions for testing strategies. It also discusses emerging alternative approaches and their potential role in supporting next-generation regulatory safety assessments.
The review aims to contribute to ongoing scientific and regulatory discussions on generating robust DNT data while supporting innovation and animal welfare-conscious decision-making.