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Use of category approaches, read-across and (Q)SAR: General considerations
Read-across has generated much attention since it may be used as an alternative approach for addressing the information requirements under regulatory programmes, notably the EU?s REACH regulation. Rea...
TR 119 – Evaluation of Systemic Health Effects Following Dermal Exposure to Chemicals
TR 119 : Evaluation of Systemic Health Effects Following Dermal Exposure to Chemicals | 26 March 2013 Technical Report no.119. Evaluation of systemic health effects following dermal exposure to chemi...
TR 118 – Development of interim guidance for the inclusion of non-extractable residues (NER) in the risk assessment of chemicals
TR 118 : Development of interim guidance for the inclusion of non-extractable residues (NER) in the risk assessment of chemicals | 29 May 2013 Technical Report no.118. Development of interim guidanc...
TR 117 – Understanding the relationship between extraction technique and bioavailability
TR 117 : Understanding the relationship between extraction technique and bioavailability | 27 May 2013 Technical Report no.117. Understanding the relationship between extraction technique and bioavai...
Refinement of the ECETOC approach to identify endocrine disrupting properties of chemicals in ecotoxicology
To use and implement an assessment scheme for the evaluation of endocrine disrupting properties of chemicals in ecotoxicology, the types of effect need to be agreed. Effects that merit further conside...
TR 116 – Category approaches, read-across, (Q)SAR
TR 116 : Category approaches, read-across, (Q)SAR | 21 November 2012 Background An accepted practice for the assessment of human health and environmental safety of chemicals is the use of models and...
Risk assessment of endocrine active chemicals: Identifying chemicals of regulatory concern
The European regulation on plant protection products (1107/2009) (EC, 2009a), the revisions to the biocides Directive (COM267) (EC, 2009b), and the regulation concerning chemicals (Regulation (EC) No....
Use of ‘Omics to Elucidate Mechanism of Action and Integration of ‘Omics in a Systems Biology Concept.
This special issue of Mutation Research may demonstrate to the reader that 'omics technologies are beginning to take their place among other routinely used approaches for chemical hazard/risk assessme...
TR 114 – ECETOC TRA version 3: Background and Rationale for the Improvements
TR 114 : ECETOC TRA version 3: Background and Rationale for the Improvements | 30 July 2012 SUMMARY The ECETOC Targeted Risk Assessment (TRA) tool was launched in 2004. The TRA consists of 3 separate...
Workshop Report 23 – ECETOC Workshop Report 23 – Epigenetics and Chemical Safety
WR 23 : ECETOC WR 23 - Epigenetics and Chemical Safety | 18 June 2012 Epigenetics is a rapidly developing and expanding biological science which will change our perception of cell biology in a profou...
2012 Art. – Workshop: Combined exposure to chemicals.
Authors : Hennes EC, Galay Burgos M, Hamer M, Pemberton M, Travis K, Rodriguez C Publisher : Regulatory Toxicology and Pharmacology 63:53-54. doi: 10.1016/j.yrtph.2012.02.008...
JACC Report 55 – Linear Polydimethylsiloxanes second edition
JACC 055 : Linear Polydimethylsiloxanes CAS No. 63148-62-9 (Second Edition) | December 2011 ISSN-0773-6339-55 print ISSN-2079-1496-55 online D-2011-3001-220 EXECUTIVE SUMMARY This report presents a...
Workshop Report 22 – Workshop on Combined Exposure to Chemicals
WR 22 : Workshop on Combined Exposure to Chemicals | October 2011 Workshop on Combined Exposure to Chemicals. 11-12 July 2011, Berlin Published October 2011 ISSN-2078-7200-22 (print) ISSN-2078-7219-...
Workshop Report 21 – Risk Assessment of Endocrine Disrupting Chemicals
WR 21 : Risk Assessment of Endocrine Disrupting Chemicals | November 2011 WR 21 Risk Assessment of Endocrine Disrupting Chemicals 9-10 May 2011, Florence ISSN-2078-7200-21 (print) ISSN-2078-7219-21...