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A Modular Approach to the Extended One-generation Reproduction Toxicity Study
This is the report of a combined initiative between the European Centre for Ecotoxicology and Toxicology of Chemicals (ECETOC) and the European Centre for the Validation of Alternative Methods (ECVAM)...
ECETOC workshop on the biological significance of DNA adducts: Summary of follow-up from an Expert Panel Meeting
This workshop on the biological significance of DNA adducts included presentations of research results in the following areas: endogenous versus exogenous adduct levels; in vitro dose?response data on...
Thresholds for Genotoxins and Their Application in Risk Assessment – Editorial
This special issue of Mutation Research presents discussion of, and new data establishing thresholds for genotoxic agents. The papers herein help to further challenge the common view that hazard equal...
Workshop Report 15 – The Probabilistic Approaches for Marine Hazard Assessment
WR 15 : The Probabilistic Approaches for Marine Hazard Assessment | June 2009 In order to discuss the potential use of probabilistic techniques in marine environmental hazard assessment, a workshop w...
Monograph 038 – Toxicity of Engineered Nanomaterials
This special issue of Toxicology Letters presents new data on the toxicology of typical manufactured nanostructured materials. It includes results from on-going industry and academic projects on the (...
Workshop Report 14 – Use of Markers for Improved Retrospective Exposure Assessment in Epidemiology Studies
WR 14 : Use of Markers for Improved Retrospective Exposure Assessment in Epidemiology Studies | February 2009 The workshop addressed the question of whether new analytical and molecular techniques wo...
TR 104 – Framework for the Integration of Human and Animal Data in Chemical Risk Assessment
TR 104 : Framework for the Integration of Human and Animal Data in Chemical Risk Assessment | January 2009 Human data form the most direct evidence for an association between health effects and expos...
TR 103 – Toxicity of Possible Impurities and By-products in Fluorocarbon Products
TR 103 : Toxicity of Possible Impurities and By-products in Fluorocarbon Products | December 2008 This report has been produced to accompany the ongoing series of reviews on fluorocarbons under the E...
DOC 046 – Potency Values from the Local Lymph Node Essay: Application to classification, labelling and risk assessment
DOC 046 : Potency Values from the Local Lymph Node Assay: Application to Classification, Labelling and Risk Assessment | December 2008 In this ECETOC Document, the use of potency values derived from...
Workshop Report 13 – Counting the Costs and Benefits of Chemical Controls: Role of Environmental Risk Assessment in Socio-Economic Analysis
WR 13 : Counting the Costs and Benefits of Chemical Controls: Role of Environmental Risk Assessment in Socio-Economic Analysis | September 2008 This report arises from a workshop organised to explor...
Workshop Report 12 – Workshop on Triggering and Waiving Criteria for the Extended One-Generation Reproduction Toxicity Study
WR 12 : Workshop on Triggering and Waiving Criteria for the Extended One-Generation Reproduction Toxicity Study | August 2008 Under the new chemicals legislation in Europe, REACH (EU, 2006), the two-...
Workshop Report 11 – Workshop on the Application of ‘Omics in Toxicology and Ecotoxicology: Case Studies and Risk Assessment
WR 11 : Workshop on the Application of 'Omics in Toxicology and Ecotoxicology: Case Studies and Risk Assessment | July 2008 To review recent progress made on the application of 'omics technologies to...
JACC Report 54 – Difluoromethane (Second Edition)
JACC 054 : Difluoromethane (HFC-32) CAS No. 75-10-5 (Second Edition) | June 2008 This report has been produced as part of the ECETOC Joint Assessment of Commodity Chemicals (JACC) programme. It updat...
DOC 045 – Triggering and Waiving Criteria for the Extended One-Generation Reproduction toxicity Study
DOC 045 : Triggering and Waiving Criteria for the Extended One-Generation Reproduction Toxicity Study | March 2008 The current ?gold standard' for the assessment of reproductive toxicity in safety eva...