Human Health and Exposure Monitoring Teams

The current 2023 research portfolio under the health and exposure programme looks as follows:

• AIMT11: Enhancing in vitroDNT Testing Strategy
  Principal investigator: Ellen Fritsche, IUF, DE
• B12.5: Assessing the relevance of the dust contribution in consumer exposure to substances from
  consumer products and articles (DustEx)
  Principal investigator: John Little, Virginia Tech, US
• B22: Tiered Methods for Quantifying Exposure to Complex Substances (“TMEx-Complex”)
  Principal investigator: Mark Parnis, Trent University, CA
• B24: Modeling exposure and biodistribution of microplastic particles in the human body
  Principal investigator: Albert Koelmans, Wageningen University, NL
• C5: Integrating Multiple Molecular-level Data Streams to understand (a) range of normal adaptation vs
  pathology and (b) molecular generated gene expression changes and persistence over time.
  Principal investigator: Jörg Hackermüller, Helmholtz Centre for Environmental Research (UFZ), DE
• C6: Toxicogenomic Approaches to Support Read-Across
  Principal investigator: George Daston, Procter & Gamble, US
• C8: MATCHING – MetAbolomics ring-Trial for CHemical groupING
  Principal investigator: Mark Viant, University of Birmingham, UK
• C9: Mining the developmental toxicity genome in the zebrafish embryo test to develop a spatio-temporal
  map on morphogenesis and associated biomarker
  Principal investigator: Sylvia Escher, Fraunhofer Institute for Toxicology and Experimental Medicine, DE
• C10: A Tiered Strategy to Assess Microplastic Inhalation
  Principal inverstigator: Tanja Hansen, ITEM Fraunhofer, DE  
• EMSG59.2: Developing a quantitative AOP for liver-mediated thyroid modulation after prenatal exposure to a xenobiotic compound in the rat. Principal investigator: Aldert Piersma, RIVM, NL

For more information on the LRI, visit their website http://www.cefic-lri.org.