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Application of the Activity Framework for Assessing Aquatic Ecotoxicology Data for Organic Chemicals
Brussels, October 2015 In a Nutshell: The relationship between the toxicity of narcotic chemicals and the octanol water partition coefficient (KOW) has been widely explored. An alternative but close...
From Bioavailability Science to Regulation of Organic Chemicals
Ortega-Calvo JJ, Harmsen J, Parsons JR, Semple KT, Aitken MD, Ajao C, Eadsforth C, Galay Burgos M, Naidu R, Oliver R, Peijnenburg WJ,, Römbke J, Streck G, Versonnen B. 2015. From Bioavailability Scie...
Thresholds in chemical respiratory sensitisation
Brussels, May 2015 A variety of chemicals are known to cause allergic sensitisation of the respiratory tract associated with allergic rhinitis and asthma. It is generally accepted that the development...
A decision-making framework for the grouping and testing of nanomaterials (DF4nanoGrouping)
The safety of nanomaterials can be ensured by undertaking animal testing only as a very last resort. This is the premise and promise of the Decision-making framework for the grouping and testing of na...
Contribution of New Technologies to Characterisation and Prediction of Adverse Effects
Rouquié D, Heneweer M, Botham J, Ketelslegers H, Markell L, Pfister T, Steiling W, Strauss V, Hennes C. 2014. Contribution of New Technologies to Characterization and Prediction of Adverse Effects....
Workshop Report 28 – Estimating toxicity thresholds for aquatic ecological communities from sensitivity distributions
WR 28 : Estimating toxicity thresholds for aquatic ecological communities from sensitivity distributions | 02/12/2014 IN A NUTSHELL Predicting the toxicity of chemicals to aquatic communities is an in...
Incorporating potency into EU classification for carcinogenicity and reproductive toxicity
Although risk assessment, assessing the potential harm of each particular exposure of a substance, is desirable, it is not feasible in many situations. Risk assessment uses a process of hazard identif...
Special Report 18 – Information to be considered in a weight-of-evidence-based PBT/vPvB assessment of chemicals (Annex XIII of REACH)
SCIENCE NEWS FLASH: ECETOC publishes report on new information and weight-of-evidence in PBT/vPvB assessment of chemicals Brussels, 1st August 2014 An ECETOC task force has reviewed the ne...
ED Pack – ECETOC publications on endocrine disrupting chemicals (updated 10 July 2014)
Publisher : This is the updated version of the package of ECETOC publications relating to endocrine disrupting chemicals originally published in October 2012. It comprises: Report commissioned by E...
TR 124 – Addendum to TR114 : Technical Basis for the TRA v3.1
TR124: Addendum to TR114 : Technical Basis for the TRA v3.1 Newsflash: In response to feedback received from users of the TRA, ECETOC has further improved the consumer portion of the model by the incl...
Environmental Exposure Assessment of Ionisable Organic Compounds
When predicting the concentration of an ionisable chemical in the environment (an important step in risk assessment), it should be realised that the compound may have different key properties (acidity...
Poorly Soluble Particles / Lung Overload
Brussels, January 2014 Despite being regarded as biologically inert, many poorly soluble substances can still cause toxicity when high concentrations of small particles are inhaled repeatedly over a...
Efficacy and safety of antidotes for acute poisoning by cyanides Volume I
Brussels, November 2013 When it happens, cyanide poisoning can have very serious neurological consequences that may result in severe disability and death. Cyanide poisoning may occur after swallowing...
Evaluation of systemic health effects following dermal exposure to chemicals
Technical Report no.119. Evaluation of systemic health effects following dermal exposure to chemicals ISSN-0773-8072-119 (print) ISSN-2079-1526-119 (online) D-2013-3001-227 Science Newsflash Expos...
Mode of Action: Recent developments, regulatory application and future work
Workshop Report no.26. Mode of Action: Recent Developments, Regulatory Applications and Future Work 21-22 February 2013, Vienna ISSN-2078-7200-26 (print) ISSN-2078-7219-26 (online) D-2013-3001-228 SCI...
