Search results
Scientific analysis of the proposed uses of T25 dose descriptor in chemical carcinogen regulation. An ECETOC Workshop Overview.
The uncertainties that surround the methods used for risk assessment of exposure to carcinogens have been highlighted by a recent document advocating an approach based on the T25 dose (the dose giving...
Skin sensitisation: New perspectives and recommendations
Various methodological aspects of skin sensitisation testing have been explored, particularly in the context of animal welfare considerations and reliability and sensitivity of test methods. Recommend...
Skin sensitisation testing in potency and risk assessment
The purpose of this article is to review, and make recommendations for, the use of relevant skin sensitization test methods, for the purposes of determination of relative potency and the threshold dos...
Monitoring, modelling and environmental exposure assessment of industrial chemicals in the aquatic environment
Monitoring and laboratory data play integral roles alongside fate and exposure models in comprehensive risk assessments. The principle in the European Union Technical Guidance Documents for risk asses...
Ecological risk assessment of endocrine disrupters
The European Centre for Ecotoxicology and Toxicology of Chemicals proposes a tiered approach for the ecological risk assessment of endocrine disruptors, integrating exposure and hazard (effects) chara...
DOC 041 – Persistent Organic Pollutants (POPs) Response to UNEP/INC/CEG-I Annex 1
DOC 041 : Persistent Organic Pollutants (POPs) Response to UNEP/INC/CEG-I Annex 1 | January 2000 An ECETOC Task Force started to work on the definition of scientific criteria for POP identification i...
DOC 040 – Comments on Recommendation from Scientific Commitee on Occupational Exposure Limits for 1,3-Butadiene
DOC 040 : Comment on Recommendation from Scientific Committee on Occupational Exposure Limits for 1,3-Butadiene | October 2000 The present document reviews the Recommendation on Occupational Exposure...
Monograph 029 – Skin Sensitisation Testing for the Purpose of Hazard Indentification and Risk Assessment
Mono 029 : Skin Sensitisation Testing for the Purpose of Hazard Indentification and Risk Assessment | September 2000 The first step in any toxicological evaluation is the accurate identification of h...
Removal of linear alkylbenzene sulfonate from a small Yorkshire stream: Contribution to GREAT-ER project # 7
An in-stream removal experiment has been carried out in Red Beck, a small stream which receives effluent from Shibden Head Sewage Treatment Works. This trickling filter works serves a purely domestic...
Monograph 028 – Threshold-Mediated Mutagens — Mutation Research Special Issue
Mono 028 : Threshold-Mediated Mutagens -- Mutation Research Special Issue| January 2000 The symposium on 'dose response and threshold effects in mutagenesis' co-sponsored by the European Environmenta...
TR 078 – Skin Sensitisation Testing: Methodological Considerations
TR 078 : Skin Sensitisation Testing: Methodological Considerations | December 1999 Skin sensitisation testing was considered last by ECETOC in Monograph No.14 (1990). Since then a revised OECD guideli...
JACC Report 39 – Tetrachloroethylene
JACC 039 : Tetrachloroethylene (CAS No. 127-18-4) | December 1999 This report presents a critical evaluation of the toxicology and ecotoxicology of tetrachloroethylene (CAS No. 127-18-4). It has been...
TR 077 – Skin and Respiratory Sensitisers: Reference Chemical Data Bank
TR 077 : Skin and Respiratory Sensitisers: Reference Chemical Data Bank | August 1999 Certain chemicals can cause occupational and consumer health problems, such as allergic contact dermatitis and all...
JACC Report 38 – Monochloroacetic Acid and its Sodium Salt
JACC 038 : Monochloroacetic Acid (CAS No.79-11-8) and its Sodium Salt (CAS No.3926-62-3) | June 1999...