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DOC 043 – Contact Sensitisation: Classification According to Potency A commentary
DOC 043 : Contact Sensitisation: Classification According to Potency: A Commentary | July 2003 The European Centre for Ecotoxicology and Toxicology of Chemicals (ECETOC) has recently published a repo...
TR 088 – Environmental Risk Assessment of Difficult Substances
TR 088 : Environmental Risk Assessment of Difficult Substances | June 2003 Experience gained from the EU environmental risk assessments has shown that certain substances have properties that complicat...
TR 087 – Contact Sensitisation: Classification According to Potency
TR 087 : Contact Sensitisation: Classification According to Potency | April 2003 Contact allergens vary substantially with regard to the relative potency with which they are able to induce skin sensit...
TR 086 – Derivation of Assessment Factors for Human Health Risk Assessment
TR 086 : Derivation of Assessment Factors for Human Health Risk Assessment | February 2003 In general, the risks to human health posed by chemical substances are assessed by the extrapolation of heter...
Monograph 033 – Application of Physiological – Toxicokinetic Modelling to Health Hazard Assessment of Chemical Substances
Mono 033 : Application of Physiological - Toxicokinetic Modelling to Health Hazard Assessment of Chemical Substances | 18 February 2003...
TR 085 – Recognition of, and Differentiation between, Adverse and Non-adverse Effects in Toxicology Studies
TR 085 : Recognition of, and Differentiation between, Adverse and Non-adverse Effects in Toxicology Studies | December 2002 This report proposes a structured approach to assist the toxicologist in arr...
TR 084 – Scientific Principles for Soil Hazard Assessment of Substances
TR 084 : Scientific Principles for Soil Hazard Assessment of Substances | July 2002 This report reviews the scientific principles that should underpin any future terrestrial (soil) hazard classificati...
TR 083 – The Use of T25 Estimates and Alternative Methods in the Regulatory Risk Assessment of Non-threshold Carcinogens in the European Union
TR 083 : The Use of T25 Estimates and Alternative Methods in the Regulatory Risk Assessment of Non-threshold Carcinogens in the European Union | December 2002 The regulation of carcinogens in the Euro...
Monograph 032 – Use of Human Data in Hazard Classification for Irritation and Sensitisation
Mono 032 : Use of Human Data in Hazard Classification for Irritation and Sensitisation | July 2002 Reference to the use of human data is made throughout the European legislation relating to the class...
Monograph 031 – Guidance on Evaluation of Reproductive Toxicity Data
Mono 031 : Guidance on Evaluation of Reproductive Toxicity Data | February 2002 The reproductive process is complex and there are many stages that are vulnerable to external influences; such influenc...
Recognition of adverse and nonadverse effects in toxicity studies
One of the most important quantitative outputs from toxicity studies is identification of the highest exposure level (dose or concentration) that does not cause treatment related effects that could be...
TR 082 – Risk Assessment in Marine Environments
TR 082 : Risk Assessment in Marine Environments | December 2001 Within Europe, risk assessments for new and existing substances for the freshwater aquatic environment are based on the standardised pro...
TR 081 – Human Acute Intoxication from Monochloroacetic Acid: Proposals for Therapy
TR 081 : Human Acute Intoxication from Monochloroacetic Acid: Proposals for Therapy | November 2001 The industrial chemical monochloroacetic acid (MCAA) is used mainly in carboxylation reactions. It i...
Monograph 030 – Genetic Susceptibility to Environmental Toxicants
Mono 030 : Genetic Susceptibility to Environmental Toxicants | October 2001...
TR 080 – Aquatic Toxicity of Mixtures
TR 080 : Aquatic Toxicity of Mixtures | July 2001 The inherent toxicity of a substance to aquatic organisms is typically determined via single species laboratory tests. Results from these tests are us...
TR 079 – Exposure Factors Sourcebook for European Populations (with Focus on UK Data)
TR 079 : Exposure Factors Sourcebook for European Populations (with Focus on UK Data) | June 2001 Risk assessment includes elements of exposure, hazard, and dose-response. The exposure component is ca...
DOC 042 – Genomics, Transcript Profiling, Proteomics and Metabonomics (GTPM) An Introduction
DOC 042 : Genomics, transcript profiling (transcriptomics), proteomics and metabonomics (GTMP). An introduction | April 2001 Genomics, transcript profiling (transcriptomics), proteomics and metabonom...
JACC Report 40 – Peracetic Acid and its Equilibrium Solutions
JACC 040 : Peracetic Acid (CAS No. 79-21-0) and its Equilibrium Solutions | January 2001 This report has been produced as part of the Joint Assessment of Commodity Chemicals (JACC) programme. It pres...