2nd ICCA MARII Workshop
12.06.2023 - 14.06.2023
Launching Soon: Polymer Analytics Task Force
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Launching Soon: Polymer Analytics Task Force

ECETOC is launching the Polymer Analytics Task Force to develop and standardize methods for analysing polymer properties essential for safety assessment. This initiative comes in response to the growi...
Opportunities to get involved – Sept. 2024
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Opportunities to get involved – Sept. 2024

Interested in recent updates and getting involved in ECETOC's work? Here's a look at a few upcoming initiatives:Be the next ECETOC representative in the ECHA ED Expert Group. We are looking for...
HSSD Tool

HSSD Tool

This software was developed by a consortium of partners to facilitate the uptake of novel approaches to estimate aquatic threshold concentrations (e.g. the concentration at which 5% of the species are exposed above their EC50, HC5).
The Human Exposure Assessment Tools Database (heatDB)

The Human Exposure Assessment Tools Database (heatDB)

heatdb is a public directory of exposure data sources as well as available tools for exposure
NanoApp

NanoApp

ECETOC’s NanoApp is a tool designed to define the boundaries of sets of similar nanoforms and to generate a justification for the REACH registration.
Targeted Risk Assessment (TRA)

Targeted Risk Assessment (TRA)

The Targeted Risk Assessment (TRA) estimates exposures to workers, consumers and the environment that arise during a series of events.
Dose Selection Task Force

Dose Selection Task Force

Background Recent opinions published by the RAC on low top dose selection in animal toxicity studies have indicated an apparent intent of increasing dosages systematically in view of the criteria u...
Mid-tier approach to aggregated exposure assessment TF

Mid-tier approach to aggregated exposure assessment TF

Background There are increasing public and regulatory concerns regarding potential health risks posed by aggregate exposure, i.e. exposure to (the same) substance from multiple sources via multiple...
Moving persistence (P) assessments into the 21st Century: Developing a new paradigm to assess degradation potential of chemicals

Moving persistence (P) assessments into the 21st Century: Developing a new paradigm to assess degradation potential of chemicals

Background Recent progress in the scientific understanding of the underlying processes of persistence and degradation has provided an opportunity to develop an improved framework and best practices...

NGRA and NAMsNext Generation Risk Assessment

Publications

Task Forces

Staged assessment: Exemplify the staged assessment process by using it to provide more information in low tonnage bands

Staged assessment: Exemplify the staged assessment process by using it to provide more information in low tonnage bands

Why? The current paradigm for identifying data (study) requirements is based upon a surrogate of exposure, namely production volume, which may under or overestimate real exposure. As presented in ...
Smart studies: Examine how in vivo studies could provide more information encompassing novel studies (and endpoints)

Smart studies: Examine how in vivo studies could provide more information encompassing novel studies (and endpoints)

Why? “Smart” or extended studies can be defined as in vivo studies that employ additional or different endpoints from conventional studies.They fall into 2 categories:those that follo...
Use of clinical data in identification of respiratory sensitisers

Use of clinical data in identification of respiratory sensitisers

Background There has been a propensity by regulators to rely primarily on health surveillance/clinical case study data (case reports, clinical databases, worker exposure studies) to classify substa...
Dose Selection Task Force

Dose Selection Task Force

Background Recent opinions published by the RAC on low top dose selection in animal toxicity studies have indicated an apparent intent of increasing dosages systematically in view of the criteria u...