2025 Annual Report
Annual Report
January 2026 news from the Sec Gen
News

January 2026 news from the Sec Gen

Dear colleagues and friends,As we begin a new year, I would like to thank you for your continued engagement and trust in ECETOC. 2026 promises to be an exciting and dynamic year, and I am pleased...
ECETOC launches Secondee Programme
News

ECETOC launches Secondee Programme

Looking for an extra challenge? A next step to help develop your career? Consider applying for our Secondee Programme!ECETOC is looking for early-career scientists currently working at a member co...
HSSD Tool

HSSD Tool

This software was developed by a consortium of partners to facilitate the uptake of novel approaches to estimate aquatic threshold concentrations (e.g. the concentration at which 5% of the species are exposed above their EC50, HC5).
The Human Exposure Assessment Tools Database (heatDB)

The Human Exposure Assessment Tools Database (heatDB)

heatdb is a public directory of exposure data sources as well as available tools for exposure
NanoApp

NanoApp

ECETOC’s NanoApp is a tool designed to define the boundaries of sets of similar nanoforms and to generate a justification for the REACH registration.
Targeted Risk Assessment (TRA)

Targeted Risk Assessment (TRA)

The Targeted Risk Assessment (TRA) estimates exposures to workers, consumers and the environment that arise during a series of events.
Chronic fish case studies towards an IATA

Chronic fish case studies towards an IATA

Why?Hazard and safety assessments for the pelagic compartment often rely on in vivo studies using a single fish species, raising ethical concerns and uncertainty in terms of extrapolation....
Estimating the environmental release of Synthetic Polymeric Microparticles from Products

Estimating the environmental release of Synthetic Polymeric Microparticles from Products

Why?REACH restriction: SPM use restricted; emissions reporting required by May 2027. Gap: No analytical methods available to measure SPM emissions. Solution: Draft SPERC-based approac...
Case Studies on Reliability and Relevance Considerations during Validation of NAMs

Case Studies on Reliability and Relevance Considerations during Validation of NAMs

Why?Validation of NAMs is often overlooked despite its importance for regulatory use. Traditional validation methods are less suitable for NAMs, which focus on key events rather than apical...

Endocrine DisruptorsRegulatory frameworks

Publications

Workshop Report no.35 – Advances in (environmental) exposure modelling: Bridging the gap between research and application. 4-5 May 2017, Brussels
Workshop Report

Workshop Report no.35 – Advances in (environmental) exposure modelling: Bridging the gap between research and application. 4-5 May 2017, Brussels

WR 35 Advances in (environmental) exposure modelling: Bridging the gap between research and application. 4-5 May 2017, Brussels Published March 2018 ISSN-2078-7219-35 (online) D-2018-3001-253...
TR 130: The ECETOC Seven Steps for the Identification of Endocrine Disrupting Properties (ECETOC 7SI-ED)
Technical Report

TR 130: The ECETOC Seven Steps for the Identification of Endocrine Disrupting Properties (ECETOC 7SI-ED)

The ECETOC 7SI-ED is recommended as a tool to assess whether or not a substance possesses endocrine disrupting properties. It is based on robust scientific principles and has been designed to be pract...
Expert Panel to better understand Endocrine Disrupter Low Doses Effects 22-23 April 2013, Barcelona
Technical Report

Expert Panel to better understand Endocrine Disrupter Low Doses Effects 22-23 April 2013, Barcelona

1. This expert panel was convened by ECETOC to discuss the issue of so-called low dose effects of endocrine disrupting chemicals (EDC), and to propose a possible research programme to throw more light...

Task Forces

Population relevance for NTOs per EU Endocrine Disruption Criteria – Expert Group

Population relevance for NTOs per EU Endocrine Disruption Criteria – Expert Group

Why? Technical guidance is still missing in response to EU scientific criteria for the determination of endocrine disrupting (ED) properties (ECHA & EFSA, 2018), to identify whether observed ad...
Substances that activate various liver receptors as endocrine disruptors

Substances that activate various liver receptors as endocrine disruptors

Why? The current development of NAMs in the field of endocrine disruption (ED) is very active as the concept of ED is evolving in various areas of toxicology including liver toxicity/xenobiotic met...
Special T4 Task Force

Special T4 Task Force

Why? A potential connection between reduction of thyroid hormones, in particular thyroxine (T4), and impaired neuronal (mental) development in children is being discussed. This debate has caused un...