Population relevance for NTOs per EU Endocrine Disruption Criteria – Expert Group
Why
Technical guidance is still missing in response to EU scientific criteria for the determination of endocrine disrupting (ED) properties (ECHA & EFSA, 2018), to identify whether observed adverse effects are relevant at the (sub)population level for non-target organisms (NTOs).
Objectives
- Develop guiding principles to establish relevance at the (sub)population level for NTOs
- Demonstrate guiding principles via case studies
Timeline and Deliverables
Work started in November 2022. The Task Force published their findings and recommendations in the journal Integrated Environmental Assessment and Management: Hazlerigg et al., 2025
Recent updates and publications
'Population Relevance of Endocrine-Mediated Effects of Pesticide and Biocide Substances – A Way Forward' - Presentation at 2024 SETAC Annual Meeting in Seville
'Population relevance of endocrine disruptors' - Presentation at 14th International Akademie Fresenius Conference - Endocrine Disruptors - 30th November 2023

