Technical Report 126

Scope of this project

This project provides exposure assessors with a review of available exposure data sources and guidance on how to incorporate data inputs for high tier aggregate exposure assessment for situations where aggregate exposure is considered relevant.

The report addresses:

  • An overview of the current human consumer exposure landscape, which includes currently available databases and tools
  • Opportunities to develop and gather exposure data related to specific product categories.
  • Aggregate exposure assessment (how to combine multiple sources and routes of exposure) including case study examples for phenoxyethanol and triclosan
  • A proposed approach for understanding if overall exposure may be dominated by few or many sources to focus any further efforts on those of more importance.

Note: In the following, aggregate exposure is defined as combined exposure to a single chemical from multiple sources and pathways. This is distinct from cumulative exposure, which is taken to be defined as exposure to multiple chemicals from multiple sources and pathways.