Special Report 19


ADME Absorption, distribution, metabolism, and excretion
AO Adverse outcome
AOP Adverse outcome pathway
AOPO Adverse outcome pathway ontology
AR Androgen receptor
BAO Bioassay ontology
CARO Common anatomy reference ontology
ChEBI Chemical Entities of Biological Interest Ontology
CL Cell Type
cpAOP Computationally predicted AOP
DTO Developmental toxicity ontology
EMAGE Mouse embryo gene expression database
EMAP Edinburgh Mouse Atlas Project
ER Oestrogen receptor
GeneIDs Gene expression identifiers
GO Gene ontology database
GPCR G protein-coupled receptor
GXD Mouse gene expression database
HPO Human phenotype ontology
IATA Integrated approaches to testing and assessment
iCSS Interactive Chemical Safety for Sustainability
KE Key event
KER Key Event Relationship
MACDP Metropolitan Atlanta Congenital Defects Program
MGI Mouse Genome Informatics database
MIE Molecular initiating event
MOA Mode of action
MPO Mammalian Phenotype Ontology database
NLP Natural Language Processing
OMIM Online Mendelian inheritance in man database
OWL Web ontology language
PBPK Physiologically-based pharmacokinetic
PMID PubMed identifier
POP Persistent organic pollutant
PPAR Peroxisome proliferator-activated receptor
QA/QC Quality assurance/quality control
RA Retinoic acid
RADH Retinaldehyde dehydrogenases
RAR Retinoic acid receptor
RDF Resource description framework
RDH Retinol dehydrogenases
RXR Retinoid X receptor
SPARQL SPARQL Protocol and RDF Query Language
STAT Signal transducer and activator of transcription
ToxRefDB (USEPA’s) Toxicity reference database
USEPA US Environmental Protection Agency
WHO World Health Organization
XML Extensible Markup Language
ZFA Zebrafish Anatomy and Development
ZFIN zebrafish model organism database