2025 Annual Report
Annual Report
January 2026 news from the Sec Gen
News

January 2026 news from the Sec Gen

Dear colleagues and friends, As we begin a new year, I would like to thank you for your continued engagement and trust in ECETOC. 2026 promises to be an exciting and dynamic year, and I am pleased...
ECETOC launches Secondee Programme
News

ECETOC launches Secondee Programme

Looking for an extra challenge? A next step to help develop your career? Consider applying for our Secondee Programme! ECETOC is looking for early-career scientists currently working at a member co...
HSSD Tool

HSSD Tool

This software was developed by a consortium of partners to facilitate the uptake of novel approaches to estimate aquatic threshold concentrations (e.g. the concentration at which 5% of the species are exposed above their EC50, HC5).
The Human Exposure Assessment Tools Database (heatDB)

The Human Exposure Assessment Tools Database (heatDB)

heatdb is a public directory of exposure data sources as well as available tools for exposure
NanoApp

NanoApp

ECETOC’s NanoApp is a tool designed to define the boundaries of sets of similar nanoforms and to generate a justification for the REACH registration.
Targeted Risk Assessment (TRA)

Targeted Risk Assessment (TRA)

The Targeted Risk Assessment (TRA) estimates exposures to workers, consumers and the environment that arise during a series of events.
Chronic fish case studies towards an IATA

Chronic fish case studies towards an IATA

Why? Hazard and safety assessments for the pelagic compartment often rely on in vivo studies using a single fish species, raising ethical concerns and uncertainty in terms of extrapolation....
Estimating the environmental release of Synthetic Polymeric Microparticles from Products

Estimating the environmental release of Synthetic Polymeric Microparticles from Products

Why? REACH restriction: SPM use restricted; emissions reporting required by May 2027. Gap: No analytical methods available to measure SPM emissions. Solution: Draft SPERC-based approac...
Case Studies on Reliability and Relevance Considerations during Validation of NAMs

Case Studies on Reliability and Relevance Considerations during Validation of NAMs

Why? Validation of NAMs is often overlooked despite its importance for regulatory use. Traditional validation methods are less suitable for NAMs, which focus on key events rather than apical...
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Latest News

ECETOC publishes 2021 annual report of activities
NewsPress Release

ECETOC publishes 2021 annual report of activities

The 2021 Annual Report is now available online!...
ECETOC Expert Group identifies research needs to enable regulatory assessment of endocrine disruption in invertebrates
Press Release

ECETOC Expert Group identifies research needs to enable regulatory assessment of endocrine disruption in invertebrates

An ECETOC Expert Group on Endocrine Disruption Assessment in Invertebrates has just published its findings on the state of the science of invertebrate endocrine disruption in relation to EU regulation...
ECETOC task force reviews external studies of targeted risk assessment tool for chemical exposure at work
Press Release

ECETOC task force reviews external studies of targeted risk assessment tool for chemical exposure at work

BRUSSELS, 4 May 2022 – In a recently released technical report available here, a task force from the Centre for chemical safety assessment (ECETOC) has reviewed external performance studies of its T...
Blanca Serrano talks to Chemical Watch about new role and future challenges
In The PressNews

Blanca Serrano talks to Chemical Watch about new role and future challenges

ECETOC's incoming Secretary General, Dr Blanca Serrano recently spoke to Chemical Watch about the path that led her to her current role as well as upcoming challenges in chemical safety assessment - a...
News

ECETOC welcomes Dr Blanca Serrano Ramón as new Secretary General

Brussels, 4 April 2022. ECETOC’s Board of Administration has appointed Dr Blanca Serrano Ramón as new Secretary General. Dr Serrano Ramón officially stepped into her new role on 1 April 2022 and w...
News

ECETOC members can contribute draft the ECHA PBT Guidance update

The ECHA PBT Expert Group has recently identified some aspects of the PBT REACH guidance (R.11) requiring update. ECHA is initiating eleven drafting groups to address the approximately fifteen update...
News

Help write the guidance to determine population relevance for wildlife per EU ED Criteria

Later this year, ECETOC will be launching an Expert Group to tackle the need for ‘Guidance to determine population relevance for wildlife per EU Endocrine Disruption Criteria’. This activity relat...
News

ECETOC Task Force is looking for clinical experts on respiratory sensitizers

The recently-launched Task Force on Use of clinical data in identification of respiratory sensitizers is inviting clinical experts to join the group. The main goal of the Task Force is to support with...
News

ECETOC Task Force is looking for data on rodent studies on poorly soluble particles

The newly-formed Task Force on Inhalation Toxicological Properties of Low Soluble Particles will launch an open call to ECETOC members to collect data on rodent studies on poorly soluble particles. Th...
News

ECETOC Members can contribute to the CARACAL CASG-Polymers discussion

After publishing three Technical Reports on the ECETOC Conceptual Framework For Polymer Risk Assessment CF4Polymers (TR 133-1, TR 133-2, TR 133-3) over the past few years, the Task Force ‘Assessing...
News

ECETOC Transformational Programme develops framework to assess safety of chemicals using ‘new approach methodologies’

Scientists from the Centre for chemical safety assessment, ECETOC, have published a new framework to assess the safety of chemicals that incorporates ‘new approach methodologies’ (NAMs), such as...
News

ECETOC workshop on carcinogenicity leads to in-depth activity in the U.S.

A recent report on assessing chemical carcinogenicity details the outcome of a Toxicology Forum workshop held in late 2020. The original proposal for this US-led gathering originated at a 2019 EC...
News

ECETOC Task Force assesses methods to improve evaluation of chemical persistence

A Task Force from the Centre for chemical safety assessment (ECETOC) has just published its findings on improving methods to evaluate a chemical’s persistence in the environment in the peer-review...
News

ECETOC Task Force develops weight-of-evidence framework for assessing chemical persistence

Brussels, 9 December 2021 – A Task Force from the Centre for chemical safety assessment (ECETOC) has just published a proposed a new framework for the assessment of chemical persistence (P) in the e...
NewsPress Release

Final report of ECETOC trilogy on polymers presents seven case studies addressing different components of safety assessment

ECETOC publishes today the final part of its trilogy on polymer safety assessment. Technical Report (TR) 133-3, Case Studies Putting the ECETOC Conceptual Framework for Polymer Risk Assessment (CF4...
NewsPress Release

Real-life study shows ECETOC’s nanoApp consistent with data gathered from animal tests

A team of scientists has carried out a series of real-life studies on nanoforms using the nanoApp designed and developed by the Centre for chemical safety assessment (ECETOC). The results of the study...
News

ECETOC General Assembly elects two new Board members

Brussels, 21 June 2021 – The Centre for chemical safety assessment (ECETOC) has elected two new members to its Board of Administration during its Annual General Meeting of 21 June 2021. Dr Jihane...
NewsPress Release

Task Force publishes second of four reports developing science-based testing strategy for maternal thyroid disruption

Brussels, 9 June 2021 – The second in a series of four reports on developing a science-based testing strategy for maternal thyroid disruption has just been published in the peer-reviewed medical jou...
NewsPress Release

ECETOC Task Force reviews scientific and legislative framework protecting Europe’s drinking water

Brussels, 27 May 2021 – An ECETOC Task Force has reviewed the current scientific and legislative framework, as well as the state of knowledge, used in protecting the sources of Europe’s drinking w...
ECETOC releases new and improved heatDB
News

ECETOC releases new and improved heatDB

A new version of ECETOC's heatDB is now available. This latest release features a better overview of search results and a tier filtering system for better accuracy. In addition to that, users ca...
Press Release

ECETOC Task Force report recommends changes to REACH’s exposure-based testing strategies for chemicals

Brussels, 5 May 2021 - A task force set up by the Centre for chemical safety assessment (ECETOC) has recommended improvements to the Exposure Based Adaptation (EBA) procedure in EU chemical legislatio...
ECETOC presents at SETAC Europe 2021 Conference
News

ECETOC presents at SETAC Europe 2021 Conference

Two ECETOC Task Forces (TF) will share results of their recent activities at the SETAC Europe 31st Annual Conference. On Monday 3 May at 16:20 CET, representatives from the  Assessing the human he...
Press Release

New ECETOC guidance says there isn’t any scientific justification for using chemical doses that cause pain or suffering in animal testing

Brussels, 10 March 2021 – In 21st century toxicology practice, there isn’t any scientific justification for selecting high doses of chemicals in animal tests which could result in lethality, pain,...
NewsPress Release

ECETOC report reviews information used to determine chemical exposure levels that are safe for human health

Brussels, 24 February 2021 – An ECETOC technical report has reviewed the existing information used to determine a substance’s ‘derived no-effect level’ (DNEL), defined as the exposure level be...

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