ABBREVIATIONS

3’-UTR                            3'-untranslated regions (of mRNAs)

AGO                                 Argonaute

AOP                                 Adverse outcome pathway

Cefic                               European Chemical Industry Council

ECETOC                          European Centre for the Ecotoxicology and Toxicology of Chemicals

esiRNA                          Endogenous short interfering RNA

HOTAIR                          Hox gene transcript antisense RNA

IL                                       Interleukin

lncRNA                          Long noncoding RNA

LRI                                    Long-range Research Initiative

MIE                                  Molecular initiating event

miRNA; miR                MicroRNA

MoA                                Mode-of-action

mRNA                             Messenger RNA

ncRNA                            Non-(protein-)coding RNA

nt                                      Nucleotide

qRT-PCR                        Quantitative real-time polymerase chain reaction

piRNA                             Piwi interacting RNA

Piwi                                 P-element induced wimpy testis in Drosophila

RA                                     Risk assessment

RNAi                                RNA interference

siRNA                             Short interfering RNA

STAT3                             Signal transducer and activator of transcription 3

xenomiR                      Xenobiotic microRNA