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  • 22 June 2009
    ECETOC's TRA task force was re-convened in 2006 with the aim of reviewing the current basis for the approach and making recommendations for further improvements. At the same time, the value of the TRA was recognised under the Commission's REACH Implementation Project (RIP) 3.2 stakeholder review activity on the development of chemical safety assessments.
  • 25 May 2009
    The ECETOC targeted risk assessment (TRA) task force reported in 2004 (Technical Report 93), and launched the supporting web-based tool shortly after. Since 2004, almost 2000 users have registered with ECETOC to gain an access to the tool and benefit from its abilities. As part of the process for maintaining the integrity and relevance of the TRA approach, ECETOC has also held a series of meetings and events with experts from member companies and regulatory authorities with the aim of identifying what further modifications may be either necessary or beneficial.

ECETOC in brief

ECETOC is a scientific forum for chemical companies to harness their specialist expertise to research, review and assess the ecotoxicology and toxicology of chemicals.

This site gives an overview of the scientific areas, corresponding initiatives (such as task forces, workshops and involvement in international initiatives) and publications undertaken by this non-profit, non-commercial organisation.



3M
Name : 3M
Akzo Nobel
Name : Akzo Nobel
Albemarle
Name : Albemarle
Arkema Group
Name : Arkema Group
Astra Zeneca
Name : Astra Zeneca
BASF
Name : BASF
Bayer
Name : Bayer
Borealis
Name : Borealis
BP
Name : BP
Cepsa
Name : Cepsa
Ciba
Name : Ciba
Clariant
Name : Clariant
Coca Cola
Name : Coca Cola
Colgate
Name : Colgate
Dow Chemical
Name : Dow Chemical
 Dow Corning
Name : Dow Corning
DSM
Name : DSM
DuPont
Name : DuPont
Evonik Degussa
Name : Evonik Degussa
Exxon Mobil
Name : Exxon Mobil
F-Hoffman la-Roche
Name : F-Hoffman la-Roche
Firmenich
Name : Firmenich
Givaudan
Name : Givaudan
Henkel
Name : Henkel
Honeywell
Name : Honeywell
Huntsman
Name : Huntsman
Ineos Chlor
Name : Ineos Chlor
International Flavors & Fragrances
Name : International Flavors & Fragrances
L'Oréal
Name : L'Oréal
Lucite
Name : Lucite
Merck
Name : Merck
Nanogate
Name : Nanogate
Nestle
Name : Nestle
Novartis
Name : Novartis
Nycomed
Name : Nycomed
Polimeri Europa
Name : Polimeri Europa
Procter & Gamble
Name : Procter & Gamble
Reckitt Benckiser
Name : Reckitt Benckiser
Repsolypf
Name : Repsolypf
Rhodia
Name : Rhodia
Rohm Haas
Name : Rohm Haas
Sasol
Name : Sasol
SC Johnson
Name : SC Johnson
Shell Chemicals
Name : Shell Chemicals
Solvay
Name : Solvay
Statoilhydro
Name : Statoilhydro
Syngenta
Name : Syngenta
Total
Name : Total
Unilever
Name : Unilever
Wacker
Name : Wacker

Toxicology is a scientific discipline involving the study of structure and mechanism related to the toxic effects of natural and chemical agents.  Ecotoxicology is concerned with the study of toxic effects on ecosystems. Both disciplines are considered vital elements of the chemical industry’s dedication to safety.  

A central concept of toxicology is that effects are dose-dependent.  The relationship between the dose needed to produce a toxic effect and the likely level of exposure determines whether there is a significant risk of harm. Scientists in industry and government are concerned to make sure that any exposure to chemicals is below the level which could cause damage to health of humans or wildlife.  At the same time, the public benefits from the technologies and products produced by the chemical industry.  Better understanding of toxicity, serves to benefit and protect both manufacturers and everyday users of chemicals. 

In Europe, common positions of the chemical industry on the state of the science concerning chemical toxicity and ecotoxicity are developed via the means of ECETOC. 

ECETOC members collaborate on strategic initiatives such as scientific workshops or task forces, which typically publish their peer-reviewed end findings.  Its initiatives look at the presence of chemicals in humans, in the environment, the effects of the chemicals, scientific methods for measuring the above, and the science of assessing the level of risk. 

ECETOC also acts as the scientific representative of the chemical industry towards European agencies and competent authorities and collaborates with ECVAM in order to develop alternatives to animal testing methods which ensure the same level of chemical safety. 

It supports the chemical industry’s long-range research initiative with the selection, monitoring and sometimes carrying out of workshops and also organises workshops on behalf of the chemical industry for some societies of toxicology

ECETOC played an important role in developing the technical guidance for manufacturers and users of chemicals implementing the forthcoming implementation of REACH (Registration, Evaluation, Authorisation and Restriction of Chemicals) legislation in Europe.  With concerns that re-evaluation of many chemicals for REACH compliance would significantly increase animal testing in mind, ECETOC also undertook initiatives to develop guidance on scientific methods to minimise this. 

The overall goal of ECETOC and its collaborating scientists is to promote the most scientific approaches to evaluating the safety of chemical products. The intended outcome is a high level of confidence in the safety of chemical products.

 

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  • WR 015 - The Probabilistic Approaches for Marine Hazard Assessment

    June 2009

    [ Abstract - Request Full PDF]

  • 2009 1 Art - A Modular Approach to the Extended One-generation Reproduction Toxicity Study

    May 2009

    [ Abstract - Request Full PDF]

  • WR 014 - Use of Markers for Improved Retrospective Exposure Assessment in Epidemiology Studies

    February 2009

    [ Abstract - Request Full PDF]

  • TR 104 - Framework for the Integration of Human and Animal Data in Chemical Risk Assessment

    January 2009

    [ Abstract - Request Full PDF]

  • DOC 046 - Potency Values from the Local Lymph Node Assay: Application to Classification, Labelling and Risk Assessment

    December 2008

    [ Abstract - Request Full PDF]

  • TR 103 - Toxicity of Possible Impurities and By-products in Fluorocarbon Products

    December 2008

    [ Abstract - Request Full PDF]

  • WR 13 - Counting the Costs and Benefits of Chemical Controls: Role of Environmental Risk Assessment in Socio-Economic Analysis

    September 2008

    [ Abstract - Request Full PDF]

  • WR 12 - Workshop on Triggering and Waiving Criteria for the Extended One-Generation Reproduction Toxicity Study

    August 2008

    [ Abstract - Request Full PDF]