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Workshops, Symposia and other meetings

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EUROECOTOX (external website)

People / Topics:

Health sciences manager

Environmental sciences manager

Chemicals programme manager

Endocrine disrupting chemicals

General information:

ECETOC e-newsletter issue 26: Summer 2014

ECETOC 2013 Annual Report

Publications catalogue

Membership benefits: increase the impact of your science

ECETOC code of practice



Recent Scientific Reports:

Information to be considered in a weight-of-evidence-based PBT/vPvB assessment of chemicals (Annex XIII of REACH). (Published July 2014 as Special Report no.18)

van Ravenzwaay et al. 2014. Editorial - Epigenetics and chemical safety
Mutation Research/Genetic Toxicology and Environmental Mutagenesis 764–765:1-2 http://dx.doi.org/10.1016/j.mrgentox.2014.01.008

Addendum to TR114: Technical Basis for the TRA v3.1 (Published December 2013 as Technical Report no.124)

Assessing Environmental Persistence. 6-7 November 2012, Paris (Published December 2013 as Workshop Report no.24)

Environmental Exposure Assessment of Ionisable Organic Compounds (Published December 2013 as Technical Report no.123)

Poorly Soluble Particles / Lung Overload (Published December 2013 as Technical Report no.122)

Activity-Based Relationships for Aquatic Ecotoxicology Data: Use of the Activity Approach to Strengthen MoA Predictions - Published December 2013 as Technical Report no.120)

Moore et al. 2013. Guidance on classification for reproductive toxicity under the globally harmonized system of classification and labelling of chemicals (GHS) Critical Reviews in Toxicology 43(10):850-891 (Doi: 10.3109/10408444.2013.854734)

Efficacy and safety of antidotes for acute poisoning by cyanides (2 volumes plus database - Published November 2013 as Technical Report no.121)

Scholz et al. 2013. A European perspective on alternatives to animal testing for environmental hazard identification and risk assessment. Regulatory Toxicology and Pharmacology 67(3):506-530. Doi 10.1016/j.yrtph.2013.10.003.

Expert Panel to better understand Endocrine Disrupter Low Doses Effects. 22-23 April 2013, Barcelona (Published October 2013 as Workshop Report no.27)

'Omics and risk assessment science. 25-26 February 2013, Málaga (Published September 2013 as Workshop Report no.25)

Patlewicz et al. 2013. Use of category approaches, read-across and (Q)SAR: General considerations. Regulatory Toxicology and Pharmacology 67(1):1-12. Doi 10.1016/j.yrtph.2013.06.002


Endocrine Disrupting Chemicals: Package of ECETOC publications

Health Sciences

May 2014

The ECETOC Secretariat is delighted to announce the appointment of Madeleine Laffont as Human Health Scientist. Within the remit of ECETOC's human health science areas, Madeleine will be managing task forces, workshops and Cefic LRI projects as well as representing ECETOC and its membership in external projects and events.

Madeleine Laffont has worked as an environmental health project management and communications consultant since 2010 (Qatar then Belgium). Prior to that, she managed a range of environmental health issues for Cefic (the European Chemical Industry Council) for eight years. Projects included Children’s Environmental Health, Indoor Air, Stakeholder Engagement on Nanotechnologies and the Health Effects of Climate Change. She has represented Cefic at EU and International arenas such as SAICM (United Nations Strategic Approach to International Chemicals Management); WHO and NGO work groups as well as Trade Unions. Her earliest professional experience was in medical writing and petrochemical journalism in London, Paris and Hong Kong. Mrs Laffont has a degree in Medicine from Imperial College, School of Medicine, London. She is an expert communicator for the Nanoforce Network, a member of Age Action Alliance, and Health Action Forum International.

Recent human health meetings

05-06 February 2014, Brussels, Belgium: 2014 Science scoping meeting on human health & human exposure in risk assessment

Supporting the Cefic-LRI

Health Effects Monitoring Team

Recent human health related publications

Moore et al. 2013. Guidance on classification for reproductive toxicity under the globally harmonized system of classification and labelling of chemicals (GHS) Critical Reviews in Toxicology 43(10):850-891 (Doi: 10.3109/10408444.2013.854734)

Patlewicz et al. 2013. Use of category approaches, read-across and (Q)SAR: General considerations. Regulatory Toxicology and Pharmacology 67(1):1-12. Doi 10.1016/j.yrtph.2013.06.002

Mode of Action: Recent developments, regulatory application and future work (Published June 2013 as Workshop Report no.26)

Evaluation of systemic health effects following dermal exposure to chemicals (Published March 2013 as Technical Report no.119)


Environmental Sciences
Malyka Galay Burgos
Environmental Sciences Manager
Dr. Malyka Galay Burgos

As the Environmental Sciences Manager within the secretariat of ECETOC, most of Malyka's work focuses on the current risk assessment and scientific criteria for the limits on the release of chemicals into the environment and the possible effects on human health: multiple stressors, chemical mixture assessment, laboratory to field assessment, structure-activity relationships; mechanisms of exposure and toxicity; sediment and water toxicity, methods and evaluation; risk and hazard assessment; biomarkers; mode of action of metal and xenobiotics; toxicokinetics; factors that modify toxicity; biomonitoring.

For this, she also seeks ways to support the further development and application of alternative approaches to hazard assessment and thereby improve the workability of REACH and good Integrated Testing Strategy (ITS) approaches that reduce costs and the use of animals while providing best quality data for the risk assessment process.

Some of her interests are in strengthening risk assessment through an evolving systems toxicology approach, utilising an understanding of chemical - biological interactions across natural compounds, emerging contaminants and potentially novel marine biotechnologies.

Task Forces

Current

Sufficiency of aquatic hazard information for environmental risk assessment

Chemical risk assessment - ecosystem services

Exploring novel ways of using SSD to establish PNECs for industrial chemicals

Guidance on interpreting endocrine disrupting effects

Targeted risk assessment

Activity-Based Relationships for Aquatic Ecotoxicology Data:  Use of the Activity Approach to Strengthen MoA Predictions

Recently completed

Development of interim guidance for the inclusion of non-extractable residues (NER) in the risk assessment of chemicals

Understanding the relationship between extraction technique and bioavailability

Development of guidance for assessing the impact of mixtures of chemicals in the aquatic environmentRisk assessment approaches for PBT/vPvB or POPs

Workshops, symposia and other meetings

Upcoming:


Recent:

11.Feb.14, Amsterdam, Netherlands: Estimating toxicity thresholds for aquatic ecological communities from sensitivity distributions

29-30.Jan.2013: 2014 Environment Progress Review

22-23.Apr.2013, Barcelona, Spain: Expert panel to better understand endocrine disrupter low doses effects

25.Feb.2013, Málaga, Spain: “Omics and Risk Assessment Science

07-08.Feb.2013: 2013 Environment Progress Review

6.Nov.2012, Paris, France: Assessing Environmental Persistence

03.May.2012, Brussels, Belgium: Targeted risk assesment version 3 workshop

28-29.Feb.2012, Brussels, Belgium: Environment Progress Review

05-06.Dec.2011, Rome, Italy: Epigenetics and chemical safety

EUROECOTOX Network:
http://www.euroecotox.eu/
Targeted risk assessment (TRA) tools

03-May-12: TRAv3 Workshop, Brussels, Belgium Development of version 3 of the TRA Tool

Targeted Risk Assessment (TRA) Tools - home page

Supporting the Cefic-LRI
Environment Monitoring Team (EMT) (Click for more details on the Cefic-LRI projects)
Latest publications

Activity-Based Relationships for Aquatic Ecotoxicology Data:  Use of the Activity Approach to Strengthen MoA Predictions (Published December 2013 as Technical Report no.120)

van Ravenzwaay B, Dekant W, Vrijhof H. 2013. Risk assessment of endocrine disrupting chemicals – Introduction to this special issue. Toxicology Letters 223(3):269-270.  Doi 10.1016/j.toxlet.2013.10.006

Assessing Environmental Persistence, 6-7 November 2012, Paris (Published December 2013 as Workshop Report no.24)

Expert Panel to better understand Endocrine Disrupter Low Doses Effects 22-23 April 2013, Barcelona (Published October 2013 as Workshop Report no.27)

Scholz et al. 2013. A European perspective on alternatives to animal testing for environmental hazard identification and risk assessment. Regulatory Toxicology and Pharmacology 67(3):506-530. Doi 10.1016/j.yrtph.2013.10.003.

'Omics and risk assessment science. 25-26 February 2013, Málaga (Published September 2013 as Workshop Report no.25)

Weltje L, Wheeler JR, Weyers A, Galay-Burgos M. 2013. Refinement of the ECETOC approach to identify endocrine disrupting properties of chemicals in ecotoxicology. Toxicology Letters Special Issue. (In Press)

Fegert I. 2013. ECETOC Firenze workshop on risk assessment of endocrine substances, including the potency concept. Toxicology Letters Special Issue. (In Press)

Lewis RW. 2013. Risk assessment of “Endocrine Substances: Guidance on Identifying Endocrine Disruptors. Toxicology Letters Special Issue. (In Press)

Development of interim guidance for the inclusion of non-extractable residues (NER) in the risk assessment of chemicals (Published June 2013 as Technical Report no.118)

Understanding the relationship between extraction technique and bioavailability (Published June 2013 as Technical Report no.117)

Bars et al. 2012. Risk assessment of endocrine active chemicals: Identifying chemicals of regulatory concern. Regulatory Toxicology and Pharmacology 64(1):143-154 Doi:10.1016/j.yrtph.2012.06.013
Awarded “Best Published Paper Advancing the Science of Risk Assessment‘ by the American Society of Toxicology (SOT) Risk Assessment Specialty Section (RASS). The paper was published in the Regulatory Toxicology and Pharmacology Journal in 2012 and can be accessed here: http://bit.ly/ecetoc-art-2012-raeac. It builds upon an earlier paper published in 2011 in the same journal.

Endocrine Disrupting Chemicals: Package of ECETOC publications on ED

Bars R, Fegert I, Gross M, Lewis D, Weltje L, Weyers A, Wheeler JR, Galay-Burgos M. 2012. Risk assessment of endocrine active chemicals: Identifying chemicals of regulatory concern. Regul.Toxicology and Pharmacology. 64(1):143-154 Doi:10.1016/j.yrtph.2012.06.013

Hennes EC, Galay Burgos M, Hamer M, Pemberton M, Travis K, Rodriguez C. 2012. Workshop: Combined exposure to chemicals. Regulatory Toxicology and Pharmacology 63:53-54. Doi: 10.1016/j.yrtph.2012.02.008

ECETOC TRA version 3: Background and Rationale for the Improvements (Published July 2012 as Technical Report no.114)

Epigenetics and Chemical Safety. 5-6 December 2011, Rome (Published May 2012 as Workshop Report no.23)

Risk Assessment of Endocrine Disrupting Chemicals. 9-10 May 2011, Florence (Published October 2011 as Workshop Report no.21)

 

To contact Malyka, please call: +32 2 675 36 00 or send an e-mail to: info@ecetoc.org

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