2025 Annual Report
Annual Report
ECETOC publishes a framework for the risk assessment of plastic additives
Press Release

ECETOC publishes a framework for the risk assessment of plastic additives

Part 1 sets out the fundamental elements, from problem formulation to risk characterisation.Brussels, 22 July 2026. The ECETOC Plastic Additives Task Force has published the first of two peer...
January 2026 news from the Sec Gen
News

January 2026 news from the Sec Gen

Dear colleagues and friends,As we begin a new year, I would like to thank you for your continued engagement and trust in ECETOC. 2026 promises to be an exciting and dynamic year, and I am pleased...
HSSD Tool

HSSD Tool

This software was developed by a consortium of partners to facilitate the uptake of novel approaches to estimate aquatic threshold concentrations (e.g. the concentration at which 5% of the species are exposed above their EC50, HC5).
The Human Exposure Assessment Tools Database (heatDB)

The Human Exposure Assessment Tools Database (heatDB)

heatdb is a public directory of exposure data sources as well as available tools for exposure
NanoApp

NanoApp

ECETOC’s NanoApp is a tool designed to define the boundaries of sets of similar nanoforms and to generate a justification for the REACH registration.
Targeted Risk Assessment (TRA)

Targeted Risk Assessment (TRA)

The Targeted Risk Assessment (TRA) estimates exposures to workers, consumers and the environment that arise during a series of events.
TRA Task Force – Worker branch

TRA Task Force – Worker branch

Why? The Worker TRA Task Force has been active since 2019, delivering projects that advance the scientific basis of the Worker Targeted Risk Assessment (TRA) tool. Its overarching objective is to e...
Immunotoxicity assessment: Addressing Challenges and Advancing Methodologies [Workshop → Task Force]​

Immunotoxicity assessment: Addressing Challenges and Advancing Methodologies [Workshop → Task Force]​

Why?Regulatory assessment of immunotoxic properties of chemicals is a complex and challenging task​ Limited regulatory guidance exists​ Lack of industry and regulatory knowledge​...
Chronic fish case studies towards an IATA

Chronic fish case studies towards an IATA

Why?Hazard and safety assessments for the pelagic compartment often rely on in vivo studies using a single fish species, raising ethical concerns and uncertainty in terms of extrapolation....
Technical Report
29.09.2021

TR 133-3 – A selection of case studies addressing different components of polymer grouping and RA to put the CF4Polymers into practice

In a nutshell

Polymers cover a broad spectrum of generally very large natural and synthetic molecules, including cellulose, waxes, and resins. They are also constituents of plastics and play essential and ubiquitous roles in everyday life.

The final part of its trilogy of Technical Reports (TR) on polymer safety assessment  looks at seven case studies assessing the usefulness of the Conceptual Framework for Polymer Risk Assessment (CF4Polymers) developed by the ECETOC Polymer Task Force and outlined in the first report of the series. The case studies also evaluate the applicability of tools, test methods and models for polymer risk assessment considered in the second TR.

This third TR confirms the value of the CF4Polymers to assess the hazard and risk of a diverse spectrum of polymers. But it also demonstrates there is no ‘one-size-fits-all’ approach to determine if any given tool, test method or model is applicable for the safety assessment of all polymers.


Find out more
https://www.ecetoc.org/wp-content/uploads/2021/10/ECETOC-TR-133-3-CF4Polymers-Case-Studies.pdf