2025 Annual Report
Annual Report
January 2026 news from the Sec Gen
News

January 2026 news from the Sec Gen

Dear colleagues and friends,As we begin a new year, I would like to thank you for your continued engagement and trust in ECETOC. 2026 promises to be an exciting and dynamic year, and I am pleased...
ECETOC launches Secondee Programme
News

ECETOC launches Secondee Programme

Looking for an extra challenge? A next step to help develop your career? Consider applying for our Secondee Programme!ECETOC is looking for early-career scientists currently working at a member co...
HSSD Tool

HSSD Tool

This software was developed by a consortium of partners to facilitate the uptake of novel approaches to estimate aquatic threshold concentrations (e.g. the concentration at which 5% of the species are exposed above their EC50, HC5).
The Human Exposure Assessment Tools Database (heatDB)

The Human Exposure Assessment Tools Database (heatDB)

heatdb is a public directory of exposure data sources as well as available tools for exposure
NanoApp

NanoApp

ECETOC’s NanoApp is a tool designed to define the boundaries of sets of similar nanoforms and to generate a justification for the REACH registration.
Targeted Risk Assessment (TRA)

Targeted Risk Assessment (TRA)

The Targeted Risk Assessment (TRA) estimates exposures to workers, consumers and the environment that arise during a series of events.
Chronic fish case studies towards an IATA

Chronic fish case studies towards an IATA

Why?Hazard and safety assessments for the pelagic compartment often rely on in vivo studies using a single fish species, raising ethical concerns and uncertainty in terms of extrapolation....
Estimating the environmental release of Synthetic Polymeric Microparticles from Products

Estimating the environmental release of Synthetic Polymeric Microparticles from Products

Why?REACH restriction: SPM use restricted; emissions reporting required by May 2027. Gap: No analytical methods available to measure SPM emissions. Solution: Draft SPERC-based approac...
Case Studies on Reliability and Relevance Considerations during Validation of NAMs

Case Studies on Reliability and Relevance Considerations during Validation of NAMs

Why?Validation of NAMs is often overlooked despite its importance for regulatory use. Traditional validation methods are less suitable for NAMs, which focus on key events rather than apical...
19.10.2022

ECETOC scientists investigate feasibility of including georeferenced data to improve ecological relevance of chemical risk assessments

The Centre for chemical safety assessment (ECETOC) has carried out a study into the feasibility of using georeferenced data to improve the ecological relevance of risk assessments.

For several decades, chemical safety assessments have followed a generic approach of comparing estimated reasonably worst-case chemical exposure concentrations to toxic thresholds designed to protect all species.

This approach, however, does not recognise the spatial and temporal variations in species distribution. Whilst the approach aims to be protective, a more precise understanding of where and when exposure and species co-occur enables chemical safety assessments to be better tailored.

In addition, environmental management practices can result in heavily modified ecosystems. For example, intensively farmed land is managed for crop production, so will not support the same diversity of species that could be sustained under different land uses.

Today, georeferenced ecological data are becoming increasingly available in enough detail to be useful for chemical risk assessments, potentially improving their environmental relevance. Spatially explicit chemical exposure estimation tools are also available.

The ECETOC Task Force (TF) analysed two aquatic case studies that explore how such data and tools could be applied to chemical safety assessment.

For each case study, the TF first estimated the distribution of chemical exposure by combining local emission and environmental information with models of what happens to the chemicals after they enter the environment. The TF then looked at the toxicity thresholds of different sorts of species present and their distribution along with local exposure estimates (i.e. the potential risk). Finally, they overlaid the risk data with the ecological status of biomonitoring sites to determine if any relationships existed.

The aim of the study was not to carry out a risk assessment of any specific chemical, but rather to demonstrate whether the integration of relevant data and potential approaches was feasible.

The TF concluded that deriving georeferenced exposure concentrations and ecological data on species distribution in the landscape was technically feasible, but that the assessment of risk is less well resolved because of the limited range of ecotoxicity data. In addition, there are not many comprehensive and consistent ecological data sets that span large geographic areas.

The challenges of adopting georeferenced environmental risk assessments over continental scales could potentially be addressed by developing and applying spatially explicit ecological effects models. Further increasing the efficiency and simplicity of assessment and interpretation methods would also be needed, including the development of guidance on how to assess spatial and temporal distributions of risk for decision making.

The Task Force’s full study has been published in the scientific journal ‘Ecotoxicology and Environmental Safety’. The full paper can be found here.