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Workshop on the improvement of the OECD 306 screening test
Workshop on the improvement of the OECD 306 screening test
at the CEFAS (Centre for Environment, Fisheries & Aquaculture Science ) laboratories, Lowestoft, UK on the 17th and 18th February 2015
Recent ECETOC workshops recommended a series of modifications and enhancements to existing OECD biodegradation screening tests to deliver more robust methods for assessing persistence [1]. This reflects the high variability and poor reliability previously reported in OECD biodegradation screening tests such as the OECD 306, marine biodegradation test [2,3,4].
The Cefic-LRi funded Eco11 [5] investigated and validated these enhancements, producing a framework for selecting the most suitable inocula cell concentration method for improved enhanced activated sludge (c.f. OECD 301) and marine tests (c.f. OECD 306). The plan is that these improvements will lead to a ring test of an enhanced OECD 306 test, which is of considerable interest to OSPAR and other regulators.
This workshop introduced the concepts and hands-on lab-based training so that any facilities interested in participating in a ring test will have the knowledge to do so. The workshop consisted of:
• Half a day of the theory, concepts and scientific evaluation of cell concentration methods and enhanced tests.
• Half a day of a practical demonstration of a cell concentration method for aqueous inocula (e.g. an enhanced OECD 306 test).
A short discussion of the practice of the Marine BODIS test was also included.
The Cefic-LRi sponsored workshop was delivered by the Eco 11 LRI team (Newcastle University and AstraZeneca) at the CEFAS (Centre for Environment, Fisheries & Aquaculture Science ) laboratories, Lowestoft, UK on the 17th and 18th February 2015.
A demonstration of Tangential Flow Filtration to Concentrate Aqueous Environmental Samples by Dr Timothy Martin & Dr Russell Davenport of Newcastle University - School of Civil Engineering & Geosciences was recorded and can be viewed on YouTube at https://youtu.be/EcT8848hDE4