2025 Annual Report
Annual Report
ECETOC publishes a framework for the risk assessment of plastic additives
Press Release

ECETOC publishes a framework for the risk assessment of plastic additives

Part 1 sets out the fundamental elements, from problem formulation to risk characterisation.Brussels, 22 July 2026. The ECETOC Plastic Additives Task Force has published the first of two peer...
January 2026 news from the Sec Gen
News

January 2026 news from the Sec Gen

Dear colleagues and friends,As we begin a new year, I would like to thank you for your continued engagement and trust in ECETOC. 2026 promises to be an exciting and dynamic year, and I am pleased...
HSSD Tool

HSSD Tool

This software was developed by a consortium of partners to facilitate the uptake of novel approaches to estimate aquatic threshold concentrations (e.g. the concentration at which 5% of the species are exposed above their EC50, HC5).
The Human Exposure Assessment Tools Database (heatDB)

The Human Exposure Assessment Tools Database (heatDB)

heatdb is a public directory of exposure data sources as well as available tools for exposure
NanoApp

NanoApp

ECETOC’s NanoApp is a tool designed to define the boundaries of sets of similar nanoforms and to generate a justification for the REACH registration.
Targeted Risk Assessment (TRA)

Targeted Risk Assessment (TRA)

The Targeted Risk Assessment (TRA) estimates exposures to workers, consumers and the environment that arise during a series of events.
Chronic fish case studies towards an IATA

Chronic fish case studies towards an IATA

Why?Hazard and safety assessments for the pelagic compartment often rely on in vivo studies using a single fish species, raising ethical concerns and uncertainty in terms of extrapolation....
Estimating the environmental release of Synthetic Polymeric Microparticles from Products

Estimating the environmental release of Synthetic Polymeric Microparticles from Products

Why?REACH restriction: SPM use restricted; emissions reporting required by May 2027. Gap: No analytical methods available to measure SPM emissions. Solution: Draft SPERC-based approac...
Case Studies on Reliability and Relevance Considerations during Validation of NAMs

Case Studies on Reliability and Relevance Considerations during Validation of NAMs

Why?Validation of NAMs is often overlooked despite its importance for regulatory use. Traditional validation methods are less suitable for NAMs, which focus on key events rather than apical...
Event
31.05.2022 - 01.06.2022

Workshop on advancing the science of exposure assessment of low molecular weight components in polymer matrices

This event is by invitation only.
For more information, please contact info@ecetoc.org

Background

Current models and concepts for determination of migration of substances from plastics are based upon the Piringer model1 and are enshrined in food contact legislation. Recent advances in model development have shown that the Piringer model describes steady-state conditions well but that diffusion within the plastic (polymer) limits migration under most realistic use and exposure conditions which are not at steady-state. This new exposure science may provide an opportunity to advance both human health and environmental exposure and risk assessments from a wide range of structural matrices including polymers, micro and macro-plastics, metals and alloys.

Regulation of polymers under REACH is imminent and requires the development of a Technical Guidance Document (TGD) on the exposure assessment of low molecular weight components from solid, insoluble polymers. In addition, food contact regulations and associated TGD relating to repeated use and short contact conditions require updating to reflect recent scientific developments. Furthermore, greater understanding of exposure from macro- and micro-plastics is urgently needed to inform on the risk assessment of these materials and reduce societal concerns.

Workshop objectives

1. Recognising the state of the science on experimental and computational exposure modelling of the release of Low Molecular Weight Compounds (LMWC) from polymers.
2. Share cross-sector expertise on available models/methods and recent developments for exposure assessment of low molecular weight components in polymer matrices, for human health and environmental risk assessments.
3. Identify areas of research and development and how to best progress.

Workshop deliverables

1. After the workshop, the Organising Committee will compile the outcome into a proposal for future research (both HH and ENV) – how can science help to address regulatory needs and societal concerns?
2. The medium/long-term objective is to support with developing a framework for regulatory validation.

Programme & abstracts

Please see the programme including the abstracts here

Venue

Renaissance Brussels Hotel
Rue du Parnasse 19
1050 Brussels
Tel: +32 2 505 2929
Hotel website