Welcome to Talia Neal-Walthall
390510

Welcome to Talia Neal-Walthall

We are pleased to welcome Talia Neal-Walthall to ECETOC as a secondee. Talia joins us to work on topics related to exposure, an area central to much of our current scientific programme. She will be wi...
September 2026 news from the Sec Gen
390509

September 2026 news from the Sec Gen

Dear members and colleagues,As we move through the year, there is a good deal to share. This has been a busy period for ECETOC, with changes to our team, our governance, and the work ahead. Let me...
HSSD Tool

HSSD Tool

This software was developed by a consortium of partners to facilitate the uptake of novel approaches to estimate aquatic threshold concentrations (e.g. the concentration at which 5% of the species are exposed above their EC50, HC5).
The Human Exposure Assessment Tools Database (heatDB)

The Human Exposure Assessment Tools Database (heatDB)

heatdb is a public directory of exposure data sources as well as available tools for exposure
NanoApp

NanoApp

ECETOC’s NanoApp is a tool designed to define the boundaries of sets of similar nanoforms and to generate a justification for the REACH registration.
Targeted Risk Assessment (TRA)

Targeted Risk Assessment (TRA)

The Targeted Risk Assessment (TRA) estimates exposures to workers, consumers and the environment that arise during a series of events.
TRA Task Force – Worker branch

TRA Task Force – Worker branch

Why? The Worker TRA Task Force has been active since 2019, delivering projects that advance the scientific basis of the Worker Targeted Risk Assessment (TRA) tool. Its overarching objective is to e...
Immunotoxicity assessment: Addressing Challenges and Advancing Methodologies [Workshop → Task Force]​

Immunotoxicity assessment: Addressing Challenges and Advancing Methodologies [Workshop → Task Force]​

Why?Regulatory assessment of immunotoxic properties of chemicals is a complex and challenging task​ Limited regulatory guidance exists​ Lack of industry and regulatory knowledge​...
Chronic fish case studies towards an IATA

Chronic fish case studies towards an IATA

Why?Hazard and safety assessments for the pelagic compartment often rely on in vivo studies using a single fish species, raising ethical concerns and uncertainty in terms of extrapolation....
Event
31.05.2022 - 01.06.2022

Workshop on advancing the science of exposure assessment of low molecular weight components in polymer matrices

This event is by invitation only.
For more information, please contact info@ecetoc.org

Background

Current models and concepts for determination of migration of substances from plastics are based upon the Piringer model1 and are enshrined in food contact legislation. Recent advances in model development have shown that the Piringer model describes steady-state conditions well but that diffusion within the plastic (polymer) limits migration under most realistic use and exposure conditions which are not at steady-state. This new exposure science may provide an opportunity to advance both human health and environmental exposure and risk assessments from a wide range of structural matrices including polymers, micro and macro-plastics, metals and alloys.

Regulation of polymers under REACH is imminent and requires the development of a Technical Guidance Document (TGD) on the exposure assessment of low molecular weight components from solid, insoluble polymers. In addition, food contact regulations and associated TGD relating to repeated use and short contact conditions require updating to reflect recent scientific developments. Furthermore, greater understanding of exposure from macro- and micro-plastics is urgently needed to inform on the risk assessment of these materials and reduce societal concerns.

Workshop objectives

1. Recognising the state of the science on experimental and computational exposure modelling of the release of Low Molecular Weight Compounds (LMWC) from polymers.
2. Share cross-sector expertise on available models/methods and recent developments for exposure assessment of low molecular weight components in polymer matrices, for human health and environmental risk assessments.
3. Identify areas of research and development and how to best progress.

Workshop deliverables

1. After the workshop, the Organising Committee will compile the outcome into a proposal for future research (both HH and ENV) – how can science help to address regulatory needs and societal concerns?
2. The medium/long-term objective is to support with developing a framework for regulatory validation.

Programme & abstracts

Please see the programme including the abstracts here

Venue

Renaissance Brussels Hotel
Rue du Parnasse 19
1050 Brussels
Tel: +32 2 505 2929
Hotel website