Welcome to Talia Neal-Walthall
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Welcome to Talia Neal-Walthall

We are pleased to welcome Talia Neal-Walthall to ECETOC as a secondee. Talia joins us to work on topics related to exposure, an area central to much of our current scientific programme. She will be wi...
September 2026 news from the Sec Gen
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September 2026 news from the Sec Gen

Dear members and colleagues,As we move through the year, there is a good deal to share. This has been a busy period for ECETOC, with changes to our team, our governance, and the work ahead. Let me...
HSSD Tool

HSSD Tool

This software was developed by a consortium of partners to facilitate the uptake of novel approaches to estimate aquatic threshold concentrations (e.g. the concentration at which 5% of the species are exposed above their EC50, HC5).
The Human Exposure Assessment Tools Database (heatDB)

The Human Exposure Assessment Tools Database (heatDB)

heatdb is a public directory of exposure data sources as well as available tools for exposure
NanoApp

NanoApp

ECETOC’s NanoApp is a tool designed to define the boundaries of sets of similar nanoforms and to generate a justification for the REACH registration.
Targeted Risk Assessment (TRA)

Targeted Risk Assessment (TRA)

The Targeted Risk Assessment (TRA) estimates exposures to workers, consumers and the environment that arise during a series of events.
TRA Task Force – Worker branch

TRA Task Force – Worker branch

Why? The Worker TRA Task Force has been active since 2019, delivering projects that advance the scientific basis of the Worker Targeted Risk Assessment (TRA) tool. Its overarching objective is to e...
Immunotoxicity assessment: Addressing Challenges and Advancing Methodologies [Workshop → Task Force]​

Immunotoxicity assessment: Addressing Challenges and Advancing Methodologies [Workshop → Task Force]​

Why?Regulatory assessment of immunotoxic properties of chemicals is a complex and challenging task​ Limited regulatory guidance exists​ Lack of industry and regulatory knowledge​...
Chronic fish case studies towards an IATA

Chronic fish case studies towards an IATA

Why?Hazard and safety assessments for the pelagic compartment often rely on in vivo studies using a single fish species, raising ethical concerns and uncertainty in terms of extrapolation....
Event
06.10.2015

Identifying limitations of the OECD water-sediment test (OECD 308) and developing suitable alternatives to assess persistence

Dübendorf (Switzerland)

The OECD guideline 308 describes a laboratory test method to assess aerobic and anaerobic transformation of organic chemicals in aquatic sediment systems and is an integral part of tiered testing strategies in different legislative frameworks for the environmental risk assessment of chemicals. Over the years, several shortcomings of the OECD guideline 308 have been identified and its usefulness for persistence and exposure assessment has been questioned.

The objectives of the 3-year project “LRI ECO18 – Improved strategy to assess chemical persistence at the water-sediment interface” were two-fold: (i) to better understand the value and information content of the existing OECD 308 protocol, and (ii) to develop an improved test strategy for assessing persistence in sediment and surface water in a consistent and robust manner.

The goal of the final stakeholder workshop on October 6, 2015, is to summarize stakeholder perspectives on the status quo of both OECD guidelines 308 and 309, and to complement this with a dissemination of the findings of the project LRI ECO18. The main focus of the workshop will be the question whether and how persistence and half-life information can be obtained from OECD 308 and 309 data.

Links: Cefic LRI ECO18 webpage