ECETOC Workshop on Applying ‘Omics Technologies in Chemicals Risk Assessment

10-12 October, 2016
NH Eurobuilding Hotel
Madrid, Spain

Objectives

With representatives from European Commission; the OECD; US-EPA; US-FDA - share and update frameworks developed by ECETOC multi-expert teams on how to aquire, analyse and apply ‘omics data. Ensue fitness for purpose.

Generate consensus of opinion on the steps needed to achieve best practices for applying ‘omics technologies in chemicals risk assessment.

Topics covered (Room Documents distributed prior to the workshop):

Establishing GLP-like Context for Collecting, Storing and Curating ‘Omics Data
Best Practices for Analysisng ‘Omics Data
Best Practices for WoE Approaches for Integrating ‘Omics Data
Best Practices for Establishing Pathways to Connect Results of ‘Omic Data to Phenotype

Context

’Omics technologies hold the promise of generating detailed information faster, more accurately and easier than ever before. These emerging technologies could help:

Reduce animal testing, with the ultimate goal of replacing animal testing altogether
Increase the number of chemicals that can be accurately and efficiently tested in a given time
Identify new and emerging risks through toxicological screening and reliable biomarkers

Yet current methodological and analytical uncertainties limit the application of ‘omics technologies. Best practice for acquiring, analysing and applying ‘omics data is needed so that information from ‘omics can be reliably verified and confidently integrated into regulatory risk assessment.

Organising Committee

Jim Bridges, University of Surrey, UK
Tim Gant, CRCE, UK
Madeleine Laffont, ECETOC, Belgium
Mark Pemberton, Systox, UK
Alan Poole, ECETOC, Belgium
Weida Tong, NCTR/FDA, USA
Ben van Ravenzwaay, BASF, Germany