Integration of Human and Animal Data in Chemical Risk Assessment

ECETOC Technical Report 104 on a “Framework for the Integration of Human and Animal Data in Chemical Risk Assessment”, published in 2009, proposes novel weight of evidence criteria for both human and animal data. This allows the highest quality database to be selected as the primary basis for standards. . The Report has helped to inform the discussions on the recently revised ECHA Guidance on the ‘Characterisation of dose response for human health’ (http://guidance.echa.europa.eu/docs/guidance_document/information_requirements_r8_en.pdf?time=1294660184).

At the same time, the Task Force has continued to develop further examples (case studies) that successfully apply the TR104 concept. A poster shown at the recent Society for Risk Analysis annual meeting in Salt Lake City (http://www.sra.org/docs/2010_SRA_Final_Program.pdf) garnered substantial interest amongst participants and from over 100 entries, it was selected “Best Poster”.

Download poster in jpeg format: http://bit.ly/ecetoc-posters-2010-ihaadicra