2025 Annual Report
Annual Report
ECETOC publishes a framework for the risk assessment of plastic additives
Press Release

ECETOC publishes a framework for the risk assessment of plastic additives

Part 1 sets out the fundamental elements, from problem formulation to risk characterisation.Brussels, 22 July 2026. The ECETOC Plastic Additives Task Force has published the first of two peer...
January 2026 news from the Sec Gen
News

January 2026 news from the Sec Gen

Dear colleagues and friends,As we begin a new year, I would like to thank you for your continued engagement and trust in ECETOC. 2026 promises to be an exciting and dynamic year, and I am pleased...
HSSD Tool

HSSD Tool

This software was developed by a consortium of partners to facilitate the uptake of novel approaches to estimate aquatic threshold concentrations (e.g. the concentration at which 5% of the species are exposed above their EC50, HC5).
The Human Exposure Assessment Tools Database (heatDB)

The Human Exposure Assessment Tools Database (heatDB)

heatdb is a public directory of exposure data sources as well as available tools for exposure
NanoApp

NanoApp

ECETOC’s NanoApp is a tool designed to define the boundaries of sets of similar nanoforms and to generate a justification for the REACH registration.
Targeted Risk Assessment (TRA)

Targeted Risk Assessment (TRA)

The Targeted Risk Assessment (TRA) estimates exposures to workers, consumers and the environment that arise during a series of events.
TRA Task Force – Worker branch

TRA Task Force – Worker branch

Why? The Worker TRA Task Force has been active since 2019, delivering projects that advance the scientific basis of the Worker Targeted Risk Assessment (TRA) tool. Its overarching objective is to e...
Immunotoxicity assessment: Addressing Challenges and Advancing Methodologies [Workshop → Task Force]​

Immunotoxicity assessment: Addressing Challenges and Advancing Methodologies [Workshop → Task Force]​

Why?Regulatory assessment of immunotoxic properties of chemicals is a complex and challenging task​ Limited regulatory guidance exists​ Lack of industry and regulatory knowledge​...
Chronic fish case studies towards an IATA

Chronic fish case studies towards an IATA

Why?Hazard and safety assessments for the pelagic compartment often rely on in vivo studies using a single fish species, raising ethical concerns and uncertainty in terms of extrapolation....
Task Force
31.10.2023

TRA Task Force – Environment branch

This Task Force is active on a number of initiatives:

  • state of the science literature review on assessment of humans exposed indirectly via the environment, to ascertain the state of the science and identify further research needs. A manuscript was published in January 2025: Verdonck et al., 2025
  • A collaborative project with National Institute for Public Health and the Environment in The Netherlands (RIVM) and Environment and Climate Change Canada (ECCC) on generation of removal predictions from the SimpleTreat model (an assessment tool for the fate of substances in wastewater treatment plants, incorporated into EUSES and Chesar). This stemmed from some ongoing work by ECCC to improve wastewater treatment removal modelling. The OECD Working Party on Exposure Assessment (WPEA) has been kept informed of this activity. A manuscript was published in January 2025: Burns et al., 2025
  • Proving technical support to a software developer who is contracted by ECETOC to migrate the TRA Environment tool from a series of excel spreadsheets into an easier-to-use standalone application.

Previous activities include:

  • In the first half of 2019, ECETOC coordinated industry’s contribution to the first stage (IT feasibility study) of the ECHA EUSES update process, via ECHA’s Technical Expert Groups (TEGs). Towards the end of 2019, ECHA confirmed its intention to develop a common chemical risk assessment tool for REACH and biocides (combining EUSES and Chesar). ECHA continued to consult with the TEGs into 2022 on technical aspects of Chesar updates and the TRA Task Force Environment branch remained engaged.