2025 Annual Report
Annual Report
January 2026 news from the Sec Gen
News

January 2026 news from the Sec Gen

Dear colleagues and friends,As we begin a new year, I would like to thank you for your continued engagement and trust in ECETOC. 2026 promises to be an exciting and dynamic year, and I am pleased...
ECETOC launches Secondee Programme
News

ECETOC launches Secondee Programme

Looking for an extra challenge? A next step to help develop your career? Consider applying for our Secondee Programme!ECETOC is looking for early-career scientists currently working at a member co...
HSSD Tool

HSSD Tool

This software was developed by a consortium of partners to facilitate the uptake of novel approaches to estimate aquatic threshold concentrations (e.g. the concentration at which 5% of the species are exposed above their EC50, HC5).
The Human Exposure Assessment Tools Database (heatDB)

The Human Exposure Assessment Tools Database (heatDB)

heatdb is a public directory of exposure data sources as well as available tools for exposure
NanoApp

NanoApp

ECETOC’s NanoApp is a tool designed to define the boundaries of sets of similar nanoforms and to generate a justification for the REACH registration.
Targeted Risk Assessment (TRA)

Targeted Risk Assessment (TRA)

The Targeted Risk Assessment (TRA) estimates exposures to workers, consumers and the environment that arise during a series of events.
Chronic fish case studies towards an IATA

Chronic fish case studies towards an IATA

Why?Hazard and safety assessments for the pelagic compartment often rely on in vivo studies using a single fish species, raising ethical concerns and uncertainty in terms of extrapolation....
Estimating the environmental release of Synthetic Polymeric Microparticles from Products

Estimating the environmental release of Synthetic Polymeric Microparticles from Products

Why?REACH restriction: SPM use restricted; emissions reporting required by May 2027. Gap: No analytical methods available to measure SPM emissions. Solution: Draft SPERC-based approac...
Case Studies on Reliability and Relevance Considerations during Validation of NAMs

Case Studies on Reliability and Relevance Considerations during Validation of NAMs

Why?Validation of NAMs is often overlooked despite its importance for regulatory use. Traditional validation methods are less suitable for NAMs, which focus on key events rather than apical...
News
07.07.2009

Launch of the new ECETOC targeted risk assessment tools

ECETOC's TRA task force was re-convened in 2006 with the aim of reviewing the current basis for the approach and making recommendations for further improvements. At the same time, the value of the TRA was recognised under the Commission's REACH Implementation Project (RIP) 3.2 stakeholder review activity on the development of chemical safety assessments.

Specifically, the TRA was seen to be the preferred approach for evaluating worker health risks (atthe Tier 1 level) and having the potential for also being adopted for evaluating consumer health risks. At the same time, the task force recognised the need to develop a more workable and pragmatic approach to environmental risk assessment using the principles laid down within the EUSES model. Many of the concepts demonstrated in the original TRA and outlined in the interim TRA webtool scoping/requirements document (insert link) are now incorporated into the planned ECHA CSA/CSR tool (CSAT). Furthermore, the specification for the CSAT foresees integrating the use of several elements of the TRA exposure estimation models.

The TRA task force have therefore sought to develop improved exposure estimation models for workers, consumer and the environment that continue to carry forward the principles that were pioneered in the original TRA web tool whilst accommodating many helpful suggestions from the stakeholder process. The revised TRA consists of 3 distinct exposure estimation models, covering workers, consumers and the environment, supported by a single integrated version of all 3 models (which is technically identical to each model but which introduces work process efficiencies for multiple data entries). Each model is downloadable through the ECETOC website.

A supporting ECETOC Technical Report that describes in detail the current structure of and basis for the revised TRA approach (for workers, consumers and the environment) will be available shortly.