ECETOC Publication Highlights Scientific Perspectives on Developmental Neurotoxicity Testing and Future Regulatory Directions
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ECETOC Publication Highlights Scientific Perspectives on Developmental Neurotoxicity Testing and Future Regulatory Directions

Brussels, 1 October 2026 – ECETOC is pleased to announce the publication of a new review article in Archives of Toxicology titled “Scientific Perspectives on In Vivo Developmental Neurotoxicity T...
Welcome to Talia Neal-Walthall
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Welcome to Talia Neal-Walthall

We are pleased to welcome Talia Neal-Walthall to ECETOC as a secondee. Talia joins us to work on topics related to exposure, an area central to much of our current scientific programme. She will be wi...
HSSD Tool

HSSD Tool

This software was developed by a consortium of partners to facilitate the uptake of novel approaches to estimate aquatic threshold concentrations (e.g. the concentration at which 5% of the species are exposed above their EC50, HC5).
The Human Exposure Assessment Tools Database (heatDB)

The Human Exposure Assessment Tools Database (heatDB)

heatdb is a public directory of exposure data sources as well as available tools for exposure
NanoApp

NanoApp

ECETOC’s NanoApp is a tool designed to define the boundaries of sets of similar nanoforms and to generate a justification for the REACH registration.
Targeted Risk Assessment (TRA)

Targeted Risk Assessment (TRA)

The Targeted Risk Assessment (TRA) estimates exposures to workers, consumers and the environment that arise during a series of events.
TRA Task Force – Worker branch

TRA Task Force – Worker branch

Why? The Worker TRA Task Force has been active since 2019, delivering projects that advance the scientific basis of the Worker Targeted Risk Assessment (TRA) tool. Its overarching objective is to e...
Immunotoxicity assessment: Addressing Challenges and Advancing Methodologies [Workshop → Task Force]​

Immunotoxicity assessment: Addressing Challenges and Advancing Methodologies [Workshop → Task Force]​

Why?Regulatory assessment of immunotoxic properties of chemicals is a complex and challenging task​ Limited regulatory guidance exists​ Lack of industry and regulatory knowledge​...
Chronic fish case studies towards an IATA

Chronic fish case studies towards an IATA

Why?Hazard and safety assessments for the pelagic compartment often rely on in vivo studies using a single fish species, raising ethical concerns and uncertainty in terms of extrapolation....
Press Release
24.03.2010

ECETOC Targeted Risk Assessment Tools (TRA) – 2010 versions

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ECETOC announce the launch of the 2010 version of the Targeted Risk Assessment (TRA) Tools.
Background:

Subsequent to the release of the TRAv2 in July 2009, ECETOC has held a series of meetings and events with experts from member companies and regulatory authorities with the aim of identifying what further modifications may be either necessary or beneficial. While the science underlying the ECETOC Targeted Risk Assessment remains unchanged, ECETOC has revised certain aspects of the Targeted Risk Assessment tool in order to:

  • take into account the latest development of the REACH Guidance Chapters R12, R14, R15, and R16
  • respond to the users' feedback and to implement the full functionality of the tools.

Changes:

The major changes in the individual tools are: Worker tool (standalone version):•revised version (debugged version) Environment assessment (integrated tool): revised version (debugged version) a comprehensive list of SPERCs has been implemented in order to facilitate refined assessments

  • the emissions from wide dispersive uses are now summed up Consumer assessment (standalone and integrated)
  • the revised use descriptor system has been implemented, together with associated Product sub Categories and related exposure determinants

Download:

The new tools are freely available via our website at: https://www.ecetoc.org/tra