Welcome to Talia Neal-Walthall
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Welcome to Talia Neal-Walthall

We are pleased to welcome Talia Neal-Walthall to ECETOC as a secondee. Talia joins us to work on topics related to exposure, an area central to much of our current scientific programme. She will be wi...
September 2026 news from the Sec Gen
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September 2026 news from the Sec Gen

Dear members and colleagues,As we move through the year, there is a good deal to share. This has been a busy period for ECETOC, with changes to our team, our governance, and the work ahead. Let me...
HSSD Tool

HSSD Tool

This software was developed by a consortium of partners to facilitate the uptake of novel approaches to estimate aquatic threshold concentrations (e.g. the concentration at which 5% of the species are exposed above their EC50, HC5).
The Human Exposure Assessment Tools Database (heatDB)

The Human Exposure Assessment Tools Database (heatDB)

heatdb is a public directory of exposure data sources as well as available tools for exposure
NanoApp

NanoApp

ECETOC’s NanoApp is a tool designed to define the boundaries of sets of similar nanoforms and to generate a justification for the REACH registration.
Targeted Risk Assessment (TRA)

Targeted Risk Assessment (TRA)

The Targeted Risk Assessment (TRA) estimates exposures to workers, consumers and the environment that arise during a series of events.
TRA Task Force – Worker branch

TRA Task Force – Worker branch

Why? The Worker TRA Task Force has been active since 2019, delivering projects that advance the scientific basis of the Worker Targeted Risk Assessment (TRA) tool. Its overarching objective is to e...
Immunotoxicity assessment: Addressing Challenges and Advancing Methodologies [Workshop → Task Force]​

Immunotoxicity assessment: Addressing Challenges and Advancing Methodologies [Workshop → Task Force]​

Why?Regulatory assessment of immunotoxic properties of chemicals is a complex and challenging task​ Limited regulatory guidance exists​ Lack of industry and regulatory knowledge​...
Chronic fish case studies towards an IATA

Chronic fish case studies towards an IATA

Why?Hazard and safety assessments for the pelagic compartment often rely on in vivo studies using a single fish species, raising ethical concerns and uncertainty in terms of extrapolation....
Press Release
18.06.2015

ECETOC Targeted Risk Assessment Tool Update to TRAv3.1

ECETOC Targeted Risk Assessment Tool Update to TRAv3.1
and Publication of related Addendum to Technical Report No. 114
on the Technical Basis for version 3 of the TRA

Brussels, June 2014

In response to feedback received from users of the TRA, ECETOC has further improved the consumer portion of the model by the inclusion of the ability to account for infrequent uses of consumer products. The changes which have been developed in cooperation with ECHA are now found as version 3.1 of the TRA and are also to be found within version 2.3 of Chesar (https://chesar.echa.europa.eu/).

A detailed explanation of the rationale for the changes is contained in an Addendum to ECETOC Technical Report 114 (just published as ECETOC Technical Report No. 124) which provides further clarification of how ECETOC has applied ‘transfer factors’ in the TRA’s prediction of oral, dermal and inhalation exposures. These improvements now enable the information contained within developments such as the DUCC Specific Consumer Exposure Determinants (http://www.ducc.eu/Activities.aspx) to be suitably processed.

The update to version 3.1 was used as an occasion to include an updated SpERC list and improvements of the functionalities by offering the export and import of single substance datasets. Version 3.1 is available both as an integrated model and a standalone version for the consumer part, and can be found at the ECETOC TRA website https://www.ecetoc.org/tools/targeted-risk-assessment-tra/ together with updated user guides for these tools and ECETOC TRA Technical Reports.

The Addendum to ECETOC Technical Report 114 has been published as ECETOC Technical Report 124: Addendum to TR114: Technical Basis for the TRA v3.1. The Summary and free PDF of the report are available at http://bit.ly/ecetoc-tr124