Welcome to Talia Neal-Walthall

We are pleased to welcome Talia Neal-Walthall to ECETOC as a secondee. Talia joins us to work on topics related to exposure, an area central to much of our current scientific programme. She will be wi...

11.09.2026 Read more

September 2026 news from the Sec Gen

Dear members and colleagues,As we move through the year, there is a good deal to share. This has been a busy period for ECETOC, with changes to our team, our governance, and the work ahead. Let me...

11.09.2026 Read more

HSSD Tool

This software was developed by a consortium of partners to facilitate the uptake of novel approaches to estimate aquatic threshold concentrations (e.g. the concentration at which 5% of the species are exposed above their EC50, HC5).

03.10.2025 Read more

The Human Exposure Assessment Tools Database (heatDB)

heatdb is a public directory of exposure data sources as well as available tools for exposure

03.10.2025 Read more

NanoApp

ECETOC’s NanoApp is a tool designed to define the boundaries of sets of similar nanoforms and to generate a justification for the REACH registration.

03.10.2025 Read more

Targeted Risk Assessment (TRA)

The Targeted Risk Assessment (TRA) estimates exposures to workers, consumers and the environment that arise during a series of events.

03.10.2025 Read more

TRA Task Force – Worker branch

Why? The Worker TRA Task Force has been active since 2019, delivering projects that advance the scientific basis of the Worker Targeted Risk Assessment (TRA) tool. Its overarching objective is to e...

04.08.2026 Read more

Immunotoxicity assessment: Addressing Challenges and Advancing Methodologies [Workshop → Task Force]

Why?Regulatory assessment of immunotoxic properties of chemicals is a complex and challenging task Limited regulatory guidance exists Lack of industry and regulatory knowledge...

30.07.2026 Read more

Chronic fish case studies towards an IATA

Why?Hazard and safety assessments for the pelagic compartment often rely on in vivo studies using a single fish species, raising ethical concerns and uncertainty in terms of extrapolation....

24.02.2026 Read more

08.02.2024

Workshop Report no.38 – Exploring best practices in quantitative AOPs (qAOPs)

In a nutshell

click the picture to watch a brief video trailer

Toxicologists, biologists, and computational modellers gathered at a workshop organised by the Centre for chemical safety assessment (ECETOC) to discuss how to develop and integrate quantitative Adverse Outcome Pathways (AOP) into EU chemical safety assessments.

AOPs are scientific ‘roadmaps’ that connect the dots between an initial molecular exposure to a substance or a stressor and any eventual harm that may occur to living organisms or ecosystems.

Downloads

Areas of work

NGRA and NAMs

Expert Report: Advancing OECD TG 309 biodegradation testing

Framework for Risk Assessment of Plastic Additives

Repeat Dose Toxicity testing workshop: From concept to application

Planetary boundary for novel entities

Welcome to Talia Neal-Walthall

September 2026 news from the Sec Gen

HSSD Tool

The Human Exposure Assessment Tools Database (heatDB)

NanoApp

Targeted Risk Assessment (TRA)

TRA Task Force – Worker branch

Immunotoxicity assessment: Addressing Challenges and Advancing Methodologies [Workshop → Task Force]

Chronic fish case studies towards an IATA

Workshop Report no.38 – Exploring best practices in quantitative AOPs (qAOPs)