2025 Annual Report
Annual Report
ECETOC publishes a framework for the risk assessment of plastic additives
Press Release

ECETOC publishes a framework for the risk assessment of plastic additives

Part 1 sets out the fundamental elements, from problem formulation to risk characterisation.Brussels, 22 July 2026. The ECETOC Plastic Additives Task Force has published the first of two peer...
January 2026 news from the Sec Gen
News

January 2026 news from the Sec Gen

Dear colleagues and friends,As we begin a new year, I would like to thank you for your continued engagement and trust in ECETOC. 2026 promises to be an exciting and dynamic year, and I am pleased...
HSSD Tool

HSSD Tool

This software was developed by a consortium of partners to facilitate the uptake of novel approaches to estimate aquatic threshold concentrations (e.g. the concentration at which 5% of the species are exposed above their EC50, HC5).
The Human Exposure Assessment Tools Database (heatDB)

The Human Exposure Assessment Tools Database (heatDB)

heatdb is a public directory of exposure data sources as well as available tools for exposure
NanoApp

NanoApp

ECETOC’s NanoApp is a tool designed to define the boundaries of sets of similar nanoforms and to generate a justification for the REACH registration.
Targeted Risk Assessment (TRA)

Targeted Risk Assessment (TRA)

The Targeted Risk Assessment (TRA) estimates exposures to workers, consumers and the environment that arise during a series of events.
Immunotoxicity assessment: Addressing Challenges and Advancing Methodologies [Workshop → Task Force]​

Immunotoxicity assessment: Addressing Challenges and Advancing Methodologies [Workshop → Task Force]​

Why?Regulatory assessment of immunotoxic properties of chemicals is a complex and challenging task​ Limited regulatory guidance exists​ Lack of industry and regulatory knowledge​...
Chronic fish case studies towards an IATA

Chronic fish case studies towards an IATA

Why?Hazard and safety assessments for the pelagic compartment often rely on in vivo studies using a single fish species, raising ethical concerns and uncertainty in terms of extrapolation....
Estimating the environmental release of Synthetic Polymeric Microparticles from Products

Estimating the environmental release of Synthetic Polymeric Microparticles from Products

Why?REACH restriction: SPM use restricted; emissions reporting required by May 2027. Gap: No analytical methods available to measure SPM emissions. Solution: Draft SPERC-based approac...
News
18.10.2022

Experts sought for 2 new Task Forces within the Human Health Transformational Programme

ECETOC is inviting experts to join two new Task Forces within its Human Health Transformational Programme.

The ECETOC Human Health Transformational Programme (HH TP) recently published a framework for chemical safety assessment incorporating New Approach Methodologies (NAMs) within REACH which outlined ways in which NAMs could be used in chemical human health assessment.  The framework has been well received and it will form part of a project being put together within the European Partnership for Alternatives to Animals (EPAA).

The HH TP Team has put forward proposals for the next steps to develop the framework in the light of the comments received from stakeholders and the insight from the new members of the team.  There are 4 work packages:

  1. Two papers to be written by the Human Health Transformational Programme Team:
  • Publish a commentary paper on the move from lists of studies to health concerns to be addressed.
  • Publish a commentary paper on the opportunities afforded by the exposure categorization concept
  1. Two Task Forces, as follows-
  • Task Force 1 to work on exemplifying the staged assessment process by using it to provide more information in low tonnage bands, working with the current classification system as far as possible.
  • Task Force 2 on examining how in vivo studies considered to be preliminary or screening within REACH could be refined provide more information by the inclusion of additional elements such as “omics”.

Experts working in industry, academia or regulatory bodies interested in joining any of these two task forces should express their interest by sending their CV (and a list of relevant publications) to info@ecetoc.org or andreea.cuciureanu@ecetoc.org by 31 October 2022, mentioning the particular contribution they can bring to the Task Force.

Applications will be screened by the ECETOC HH TP members for suitability and overall fit; special attention will be given to ensure gender/age diversity in the final composition of the Task Forces.

Selected Task Force members will take part in the organisation of kick-off meetings for each Task Force, which are anticipated to take place in November 2022.