2025 Annual Report
Annual Report
ECETOC publishes a framework for the risk assessment of plastic additives
Press Release

ECETOC publishes a framework for the risk assessment of plastic additives

Part 1 sets out the fundamental elements, from problem formulation to risk characterisation.Brussels, 22 July 2026. The ECETOC Plastic Additives Task Force has published the first of two peer...
January 2026 news from the Sec Gen
News

January 2026 news from the Sec Gen

Dear colleagues and friends,As we begin a new year, I would like to thank you for your continued engagement and trust in ECETOC. 2026 promises to be an exciting and dynamic year, and I am pleased...
HSSD Tool

HSSD Tool

This software was developed by a consortium of partners to facilitate the uptake of novel approaches to estimate aquatic threshold concentrations (e.g. the concentration at which 5% of the species are exposed above their EC50, HC5).
The Human Exposure Assessment Tools Database (heatDB)

The Human Exposure Assessment Tools Database (heatDB)

heatdb is a public directory of exposure data sources as well as available tools for exposure
NanoApp

NanoApp

ECETOC’s NanoApp is a tool designed to define the boundaries of sets of similar nanoforms and to generate a justification for the REACH registration.
Targeted Risk Assessment (TRA)

Targeted Risk Assessment (TRA)

The Targeted Risk Assessment (TRA) estimates exposures to workers, consumers and the environment that arise during a series of events.
Chronic fish case studies towards an IATA

Chronic fish case studies towards an IATA

Why?Hazard and safety assessments for the pelagic compartment often rely on in vivo studies using a single fish species, raising ethical concerns and uncertainty in terms of extrapolation....
Estimating the environmental release of Synthetic Polymeric Microparticles from Products

Estimating the environmental release of Synthetic Polymeric Microparticles from Products

Why?REACH restriction: SPM use restricted; emissions reporting required by May 2027. Gap: No analytical methods available to measure SPM emissions. Solution: Draft SPERC-based approac...
Case Studies on Reliability and Relevance Considerations during Validation of NAMs

Case Studies on Reliability and Relevance Considerations during Validation of NAMs

Why?Validation of NAMs is often overlooked despite its importance for regulatory use. Traditional validation methods are less suitable for NAMs, which focus on key events rather than apical...
News
06.02.2025

ECETOC Activity Update

Have a look at what's coming up in the next few weeks. If you're interested in taking part, get in contact with us!

DEVELOPMENT OF NEW TRA ENVIRONMENT SOFTWARE: ECETOC has contracted ProtoQSAR to migrate the Environment TRA tool from its current form (series of excel spreadsheets) into an easier-to-use standalone application. The aim is to maintain the current functionality of the overall functionality/flexibility of the tool. The tool will also be updated in line with recent Chesar updates (e.g. update to SimpleTreat and inclusion of in-sewer removal).

Similar migrations for the Worker and Consumer TRA tools may be considered in the future.The ECETOC TRA Environment Task force will maintain a regular dialogue with ProtoQSAR experts. If you would like to participate to these discussions and help shape the tool, please contact Lucy Wilmot.

LAUNCHING SOONECETOC is launching a Task Force to develop case studies and a framework for an intelligent, integrative, and innovative evaluation of chronic fish toxicity. The aim is to make best use of available data (including new approach methodologies (NAMs)) and reduce testing on vertebrate animals, whilst providing more predictivity e.g. on mechanism of action. The details are still under refinement, but we plan to send a Call for Nominations in Q1. For more information, please contact Lucy Wilmot.

JOIN THE SHADOW GROUP FOR THE ECHA ED EG: We are estabilshing a shadow group to support ECETOC’s participation in the ECHA Endocrine Disruptors Expert Group (ED EG). The primary objective of this group will be to collaborate with ECETOC's designated representative to determine key topics and inputs for the ED EG meetings. Volunteers are invited to be in touch asap. Interested? Contact Megan D’souza.

NEW TASK FORCE ANNOUNCEMENT: A new task force recently kicked off focusing on Case Studies on Reliability and Relevance Considerations during Validation of NAMs. Anyone interested in participating can reach out to Megan D’souza.