2025 Annual Report
Annual Report
We’re Hiring: Join the ECETOC Team as a Trainee!
News

We’re Hiring: Join the ECETOC Team as a Trainee!

Are you passionate about science, regulatory toxicology, and making a real-world impact at the intersection of industry, academia, and policy? ECETOC is excited to announce that we’re looking for a...
ECETOC publishes a framework for the risk assessment of plastic additives
Press Release

ECETOC publishes a framework for the risk assessment of plastic additives

Part 1 sets out the fundamental elements, from problem formulation to risk characterisation.Brussels, 22 July 2026. The ECETOC Plastic Additives Task Force has published the first of two peer...
HSSD Tool

HSSD Tool

This software was developed by a consortium of partners to facilitate the uptake of novel approaches to estimate aquatic threshold concentrations (e.g. the concentration at which 5% of the species are exposed above their EC50, HC5).
The Human Exposure Assessment Tools Database (heatDB)

The Human Exposure Assessment Tools Database (heatDB)

heatdb is a public directory of exposure data sources as well as available tools for exposure
NanoApp

NanoApp

ECETOC’s NanoApp is a tool designed to define the boundaries of sets of similar nanoforms and to generate a justification for the REACH registration.
Targeted Risk Assessment (TRA)

Targeted Risk Assessment (TRA)

The Targeted Risk Assessment (TRA) estimates exposures to workers, consumers and the environment that arise during a series of events.
TRA Task Force – Worker branch

TRA Task Force – Worker branch

Why? The Worker TRA Task Force has been active since 2019, delivering projects that advance the scientific basis of the Worker Targeted Risk Assessment (TRA) tool. Its overarching objective is to e...
Immunotoxicity assessment: Addressing Challenges and Advancing Methodologies [Workshop → Task Force]​

Immunotoxicity assessment: Addressing Challenges and Advancing Methodologies [Workshop → Task Force]​

Why?Regulatory assessment of immunotoxic properties of chemicals is a complex and challenging task​ Limited regulatory guidance exists​ Lack of industry and regulatory knowledge​...
Chronic fish case studies towards an IATA

Chronic fish case studies towards an IATA

Why?Hazard and safety assessments for the pelagic compartment often rely on in vivo studies using a single fish species, raising ethical concerns and uncertainty in terms of extrapolation....
News
03.04.2020

ECETOC study investigates the extrapolation of aquatic environmental safety assessment data to soils and sediments

A study by ECETOC has investigated the extrapolation of data from ecotoxicity tests carried out in water to assess toxicity in soils and sediments, using the Equilibrium Partitioning Methodology (EPM).

When assessing a chemical’s potential effects on the environment, there is often much more data available on aquatic toxicity than on the possible impact on species from other compartments such as soil and sediment. This is because lower-tier environmental safety assessments typically rely on aquatic toxicity data only. The scheme for classification and labelling for environmental hazards also uses only aquatic hazard data. Results from non-aquatic testing are therefore rather scarce.

However, current regulation requires chemical safety assessment to cover other environmental compartments, such as soils and sediments. Until now, there has been no clear consensus about the extent to which aquatic toxicity data are sufficient for managing safety in other compartments.

The ECETOC Task Force therefore compiled and analysed a database of substances for which aquatic ecotoxicity data and soil and/or sediment ecotoxicity data are simultaneously available. A large number of datapoints was used in the study. A thorough assessment of the quality of the data would have been optimal, but was not within the scope of the work.

Overall, the Task Force concluded that the dataset used limited the ability to draw concrete conclusions on the mechanistic validity of EPM. However, the findings do not contradict previous studies that demonstrate that EPM is fit for purpose to support environmental risk assessments when information on soil/sediment toxicity are limited or testing is not feasible. Known exceptions are sediments with high soot content as well as specific sediment organisms that live on top of the sediment.

Based on their work, the Task Force has made a number of suggestions for further work in this area.

The full report, Sufficiency of aquatic hazard data for environmental risk assessment in sediment and soil, can be found here.