2025 Annual Report
Annual Report
January 2026 news from the Sec Gen
News

January 2026 news from the Sec Gen

Dear colleagues and friends,As we begin a new year, I would like to thank you for your continued engagement and trust in ECETOC. 2026 promises to be an exciting and dynamic year, and I am pleased...
ECETOC launches Secondee Programme
News

ECETOC launches Secondee Programme

Looking for an extra challenge? A next step to help develop your career? Consider applying for our Secondee Programme!ECETOC is looking for early-career scientists currently working at a member co...
HSSD Tool

HSSD Tool

This software was developed by a consortium of partners to facilitate the uptake of novel approaches to estimate aquatic threshold concentrations (e.g. the concentration at which 5% of the species are exposed above their EC50, HC5).
The Human Exposure Assessment Tools Database (heatDB)

The Human Exposure Assessment Tools Database (heatDB)

heatdb is a public directory of exposure data sources as well as available tools for exposure
NanoApp

NanoApp

ECETOC’s NanoApp is a tool designed to define the boundaries of sets of similar nanoforms and to generate a justification for the REACH registration.
Targeted Risk Assessment (TRA)

Targeted Risk Assessment (TRA)

The Targeted Risk Assessment (TRA) estimates exposures to workers, consumers and the environment that arise during a series of events.
Chronic fish case studies towards an IATA

Chronic fish case studies towards an IATA

Why?Hazard and safety assessments for the pelagic compartment often rely on in vivo studies using a single fish species, raising ethical concerns and uncertainty in terms of extrapolation....
Estimating the environmental release of Synthetic Polymeric Microparticles from Products

Estimating the environmental release of Synthetic Polymeric Microparticles from Products

Why?REACH restriction: SPM use restricted; emissions reporting required by May 2027. Gap: No analytical methods available to measure SPM emissions. Solution: Draft SPERC-based approac...
Case Studies on Reliability and Relevance Considerations during Validation of NAMs

Case Studies on Reliability and Relevance Considerations during Validation of NAMs

Why?Validation of NAMs is often overlooked despite its importance for regulatory use. Traditional validation methods are less suitable for NAMs, which focus on key events rather than apical...
Technical Report
29.08.1996

TR 071 – Inventory of Critical Reviews on Chemicals

TR 071 : Inventory of Critical Reviews on Chemicals | August 1996

The United Nations Environment Programme (UNEP), through its International Register of Potentially Toxic Chemicals (IRPTC), and the European Centre for the Ecotoxicology and Toxicology of Chemicals (ECETOC), are jointly operating an Inventory of Critical Reviews on Chemicals (ICRC).

The ICRC presents the work of 40 organisations or agencies involved in reviewing or evaluating data pertaining to health or environmental hazards posed by chemicals.  The content of the ICRC depends on the voluntary contribution of these international, governmental and non-governmental organisations, including industry.

The ICRC contains a description of these organisations, an outline of the general content of the series of reviews they produce (including descriptors) and information on the preparation process of these reviews together with their year of publication or their stage of preparation (in preparation or planned).  Forty six series of reviews have been identified as fulfilling the criteria for inclusion in the ICRC as critical reviews.  Six other series of interest have been added.  There are more than 9500 critical reviews recorded in the ICRC.  Contact points, where further information and publications can be obtained, are given at the end of the description of each organisation.

Included in the ICRC are more than 3900 chemicals reviewed or evaluated by one or more organisations.  The chemicals are tabulated in alphabetical order, using their common names (name most frequently reported by contributors to the ICRC).  Cross-reference tables with other reported names and with Chemical Abstracts Service (CAS) Registry Numbers should facilitate locating chemicals in the main table.

The purpose of the ICRC is to inform both producers and users of critical reviews on the existence of such reviews and about their content, planning and preparation stages. Through this information, the production of risk assessment documents may be better coordinated nationally and internationally, and costly duplication of efforts can be avoided. The ICRC is also useful in establishing international priorities for chemical evaluation.