Task Forces
Guidance on interpreting endocrine disrupting effects within the constraints of REACH and the revised 91/414 directive
The finding of this Task force were published as Technical Report No. 106 (published June 2009).
Background
REACH has indicated that substances (e.g. intermediates, raw materials and formulation i...
Development of guidance for assessing the impact of mixtures of chemicals in the aquatic environment
Environmental Sciences Manager Malyka Galay Burgos
Administrative Assistant Christine Yannakas
The findings of the task force were published in October 2011 as ECETOC Technical Report No.111; "Dev...
Understanding the relationship between extraction technique and bioavailability
Completed task force: The task force published its findings in June 2013 as Technical Report no.117: Understanding the relationship between extraction technique and bioavailability
Environmental Sc...
ERA of ionisable compounds
Chemicals Programme Manager Henk Vrijhof
Administrative Assistant: Sonia Pulinckx
Background
The release of “ionisable compounds' (where behaviour depends on pH, ionic strength, etc) into the...
Development of interim guidance for the inclusion of non-extractable residues (NER) in the risk assessment of chemicals
Completed task force: The task force published its findings in June 2013 as Technical Report no.118; Development of interim guidance for the inclusion of non-extractable residues (NER) in the risk a...
Low-dose interactions
Health Sciences Manager Christa Hennes
Administrative Assistant Christine Yannakas
The task force published its findings in July 2012 as Technical Report No. 115; "Effects of Chemical Co-exposures...
Potency in carcinogenicity and reproductive toxicity classification
Potency in carcinogenicity and reproductive toxicity classification
Classification should give guidance on the potential hazards of chemicals. Once the nature of the hazard is known, potency is the...
Guidance for classification of reproductive toxicants under GHS
Health Sciences Manager Christa Hennes
Administrative Assistant Christine Yannakas
Background
The Globally Harmonised System of Classification and Labelling of Chemicals (GHS) has been introduc...
Chemical risk assessment – ecosystem services
Background
Assessing the risks of chemicals to man and the environment is based on the concept of comparing exposure to chemicals with their respective hazardous properties. However, there are diff...
Sufficiency of aquatic hazard information for environmental risk assessment
Background
Currently, there is no clear consensus concerning whether available information on the aquatic hazard of substances is sufficient for determining whether or not an environmental risk ass...
Thresholds in respiratory sensitisation
Task Force Manager Alan Poole
Administrative Assistant Christine Yannakas
Background
Respiratory sensitisation gains increasing importance in EU regulations as an endpoint driving restrictive m...
Grouping of nanomaterials
Background and Outcome
Nanomaterials and nanotechnology-enabled products have to be safe. It is imperative that they do not harm humans or the environment.
As more and more nanotechnology-enable...
PBT criteria (Annex XIII of REACH)
Outcome: August 2014
The task force has published its findings as ECETOC Special Report 18: Information to be considered in a weight-of-evidence-based PBT/vPvB assessment of chemicals (Annex XIII o...
Assessment and evaluation of risks resulting from dermal exposure to chemicals
Completed task force: The task force published its findings in March 2013 as Technical Report no.119: Evaluation of systemic health effects following dermal exposure to chemicals
Health Sciences Ma...
Activity-Based Relationships for Aquatic Ecotoxicology Data: Use of the Activity Approach to Strengthen MoA Predictions
Environmental Sciences Manager: Malyka Galay Burgos
Administrative Assistant Sonia Pulinckx
Background
Two ECETOC Task Forces on the risk assessment of PBTs have produced recommendations to ena...
Guidance on interpreting endocrine disrupting effects within the constraints of REACH and the revised 91/414 directive
The finding of this Task force were published as Technical Report No. 106 (published June 2009).
Background
REACH has indicated that substances (e.g. intermediates, raw materials and formulation i...
Guidance for classification of reproductive toxicants under GHS
Health Sciences Manager Christa Hennes
Administrative Assistant Christine Yannakas
Background
The Globally Harmonised System of Classification and Labelling of Chemicals (GHS) has been introduc...
Exploring novel ways of using SSD to establish PNECs for industrial chemicals
Environmental Sciences Manager Malyka Galay Burgos
Background
An ECETOC workshop on "Probabilistic Approaches for Marine Hazard Assessment" was held in Oslo, June 2008. The main outcomes are doc...
Mode of Action and Identification of Adverse vs. Non-adverse Effects
Task Force Manager Alan Poole
Administrative Assistant Christine Yannakas
Background
The scientifically sound discrimination between adverse and non-adverse effects has always been a key elem...
Chemical risk assessment – ecosystem services
Environmental Sciences Manager Malyka Galay Burgos
Administrative Assistant Sonia Pulinckx
Background
Assessing the risks of chemicals to man and the environment is based on the concept of comp...
Guidance for Effective Use of Human Exposure Data in Risk Assessment of Chemicals
Background
The structures and processes by which risks are assessed and managed should themselves be risk-informed. This requires that full and proper account needs to be taken of the human exposur...