2025 Annual Report
Annual Report
ECETOC publishes a framework for the risk assessment of plastic additives
Press Release

ECETOC publishes a framework for the risk assessment of plastic additives

Part 1 sets out the fundamental elements, from problem formulation to risk characterisation.Brussels, 22 July 2026. The ECETOC Plastic Additives Task Force has published the first of two peer...
January 2026 news from the Sec Gen
News

January 2026 news from the Sec Gen

Dear colleagues and friends,As we begin a new year, I would like to thank you for your continued engagement and trust in ECETOC. 2026 promises to be an exciting and dynamic year, and I am pleased...
HSSD Tool

HSSD Tool

This software was developed by a consortium of partners to facilitate the uptake of novel approaches to estimate aquatic threshold concentrations (e.g. the concentration at which 5% of the species are exposed above their EC50, HC5).
The Human Exposure Assessment Tools Database (heatDB)

The Human Exposure Assessment Tools Database (heatDB)

heatdb is a public directory of exposure data sources as well as available tools for exposure
NanoApp

NanoApp

ECETOC’s NanoApp is a tool designed to define the boundaries of sets of similar nanoforms and to generate a justification for the REACH registration.
Targeted Risk Assessment (TRA)

Targeted Risk Assessment (TRA)

The Targeted Risk Assessment (TRA) estimates exposures to workers, consumers and the environment that arise during a series of events.
Chronic fish case studies towards an IATA

Chronic fish case studies towards an IATA

Why?Hazard and safety assessments for the pelagic compartment often rely on in vivo studies using a single fish species, raising ethical concerns and uncertainty in terms of extrapolation....
Estimating the environmental release of Synthetic Polymeric Microparticles from Products

Estimating the environmental release of Synthetic Polymeric Microparticles from Products

Why?REACH restriction: SPM use restricted; emissions reporting required by May 2027. Gap: No analytical methods available to measure SPM emissions. Solution: Draft SPERC-based approac...
Case Studies on Reliability and Relevance Considerations during Validation of NAMs

Case Studies on Reliability and Relevance Considerations during Validation of NAMs

Why?Validation of NAMs is often overlooked despite its importance for regulatory use. Traditional validation methods are less suitable for NAMs, which focus on key events rather than apical...
Technical Report
04.10.2023

TR 141 – Comparison of measured and modelled short-term inhalation and dermal exposure

In a nutshell

An ECETOC Task Force has carried out further comparisons of modelled results from its Targeted Risk Assessment (TRA) Worker tool with actual measurement data for inhalation and dermal exposure to chemicals in workplaces. The tool is used by companies in Europe to model exposure assessments of chemical substances for REACH dossiers.

 

The Task Force’s work demonstrated that the current version of the Worker tool (TRAv3.1) overestimated the actual measured exposure in most cases. Together with the results from a previous analysis, sufficient information was available to refine the TRAv3.1 tool. A new version of the TRA Worker tool (v3.2), available from mid-October 2023, will feature targeted changes, described in TR No. 141, that further increase the conservatism of the tool.


Find out more
https://www.ecetoc.org/wp-content/uploads/2023/10/TR-141-Comparison-of-measured-and-modelled-short-term-inhalation-and-dermal-exposure_20230914.pdf