We’re Hiring: Join the ECETOC Team as a Trainee!
390494

We’re Hiring: Join the ECETOC Team as a Trainee!

Are you passionate about science, regulatory toxicology, and making a real-world impact at the intersection of industry, academia, and policy? ECETOC is excited to announce that we’re looking for a...
ECETOC publishes a framework for the risk assessment of plastic additives
390456

ECETOC publishes a framework for the risk assessment of plastic additives

Part 1 sets out the fundamental elements, from problem formulation to risk characterisation.Brussels, 22 July 2026. The ECETOC Plastic Additives Task Force has published the first of two peer...
HSSD Tool

HSSD Tool

This software was developed by a consortium of partners to facilitate the uptake of novel approaches to estimate aquatic threshold concentrations (e.g. the concentration at which 5% of the species are exposed above their EC50, HC5).
The Human Exposure Assessment Tools Database (heatDB)

The Human Exposure Assessment Tools Database (heatDB)

heatdb is a public directory of exposure data sources as well as available tools for exposure
NanoApp

NanoApp

ECETOC’s NanoApp is a tool designed to define the boundaries of sets of similar nanoforms and to generate a justification for the REACH registration.
Targeted Risk Assessment (TRA)

Targeted Risk Assessment (TRA)

The Targeted Risk Assessment (TRA) estimates exposures to workers, consumers and the environment that arise during a series of events.
TRA Task Force – Worker branch

TRA Task Force – Worker branch

Why? The Worker TRA Task Force has been active since 2019, delivering projects that advance the scientific basis of the Worker Targeted Risk Assessment (TRA) tool. Its overarching objective is to e...
Immunotoxicity assessment: Addressing Challenges and Advancing Methodologies [Workshop → Task Force]​

Immunotoxicity assessment: Addressing Challenges and Advancing Methodologies [Workshop → Task Force]​

Why?Regulatory assessment of immunotoxic properties of chemicals is a complex and challenging task​ Limited regulatory guidance exists​ Lack of industry and regulatory knowledge​...
Chronic fish case studies towards an IATA

Chronic fish case studies towards an IATA

Why?Hazard and safety assessments for the pelagic compartment often rely on in vivo studies using a single fish species, raising ethical concerns and uncertainty in terms of extrapolation....
Event
23.10.2014 - 24.10.2014

Fish and amphibian embryos as alternative models in toxicology and teratology

When 23 – 24 Oct 2014

Where  Aulnay-sous-Bois/Paris, France (map)

Description

Fish and amphibian embryo models are highly popular in the area of toxicology, both in research, industry and potential regulatory application. These models exhibit a number of advantages which make them superior and/or complementary to others. In compliance with international animal welfare regulations, the fish and amphibian embryo models provide an ethically acceptable small scale analysis system with the complexity of a complete organism. A suite of available advanced methodologies allows various types of experimental approaches ranging from phenotypic observations, functional assays to “omics” analysis. The ultimate goal of the symposium is to promote the development of the fish and frog embryo models as potential alternatives to animal testing.

Two first very succesful symposia were held in 2010 and 2012 with a strong focus on the zebrafish model. While the zebrafish will remain one of the most important model our symposium is open to other fish and amphibian species with similar features. The symposium aims to bring together scientists using fish and frog embryo models, exchange knowledge, ideas and latest developments in the field of toxicology and teratology. Invited lectures will focus on specific topics. Breakout sessions will allow to identify major advantages, limitations, new fields and future research needs of the fish/amphibian embryo model and to establish collaborations.