Advances in consumer exposure science: Data, Modelling and Aggregate Exposure Assessment

01 December 2015, Park Inn Brussels Midi, Brussels, Belgium POSTPONED to 26th January 2016

This Workshop was originally scheduled to take place 01 December 2015 but due to the security alert in Brussels has been moved to 26 January 2016

Background

Although exposure-driven risk assessment has long been included in the toxicological and safety assessment of chemicals, advances in Toxicology in the 21^st Century now highlight that exposure assessment is crucial.  Describing external and internal human exposure dose through modelling facilitates the targeted use of emerging toxicological tools for safety assessments.  Benefits of reliable exposure assessments include:

• Accurate estimation of exposure.  This reduces uncertainty, thereby enabling risk assessment to be a truer reflection of the actual situation.
• Improved integrity of the assessment by enabling targeted and prioritised focus on the populations exposed to the greatest risks.
• Preventing/reducing the need for animal testing.
• Implementing refined approaches to exposure assessment requires consideration of:
  - Data availability.
  - Specialised tools, data sets and computational power.
  - Standard approaches for the collection and sharing of appropriate data on consumer exposure.
  - Criteria for selecting optimal exposure databases and modelling tools available.

Aims

1) Present and review the current state of consumer exposure science by examining data needs, sources (including novel data sources), tools, gaps and the latest innovations.

2) Develop consensus on key gaps that should be filled and identify what the major research needs are, including how to address aggregate consumer exposure.

3) With the help of case studies, examine the potential for the refinement of exposure assessment using appropriate tools and techniques which are fit for purpose.

Structure

The workshop consists of a series of 20-minute talks followed by syndicate sessions (typically 10 people each) in which syndicate groups work with a number of fixed questions.

Organising Committee

Madeleine Laffont, ECETOC                                      Mark Pemberton, Systox

Chris Money, Cynara Consulting                               Carlos Rodriguez, P&G

Cian O’Mahony, Creme Global                                 Sarah Tozer, P&G