2025 Annual Report
Annual Report
January 2026 news from the Sec Gen
News

January 2026 news from the Sec Gen

Dear colleagues and friends,As we begin a new year, I would like to thank you for your continued engagement and trust in ECETOC. 2026 promises to be an exciting and dynamic year, and I am pleased...
ECETOC launches Secondee Programme
News

ECETOC launches Secondee Programme

Looking for an extra challenge? A next step to help develop your career? Consider applying for our Secondee Programme!ECETOC is looking for early-career scientists currently working at a member co...
HSSD Tool

HSSD Tool

This software was developed by a consortium of partners to facilitate the uptake of novel approaches to estimate aquatic threshold concentrations (e.g. the concentration at which 5% of the species are exposed above their EC50, HC5).
The Human Exposure Assessment Tools Database (heatDB)

The Human Exposure Assessment Tools Database (heatDB)

heatdb is a public directory of exposure data sources as well as available tools for exposure
NanoApp

NanoApp

ECETOC’s NanoApp is a tool designed to define the boundaries of sets of similar nanoforms and to generate a justification for the REACH registration.
Targeted Risk Assessment (TRA)

Targeted Risk Assessment (TRA)

The Targeted Risk Assessment (TRA) estimates exposures to workers, consumers and the environment that arise during a series of events.
Chronic fish case studies towards an IATA

Chronic fish case studies towards an IATA

Why?Hazard and safety assessments for the pelagic compartment often rely on in vivo studies using a single fish species, raising ethical concerns and uncertainty in terms of extrapolation....
Estimating the environmental release of Synthetic Polymeric Microparticles from Products

Estimating the environmental release of Synthetic Polymeric Microparticles from Products

Why?REACH restriction: SPM use restricted; emissions reporting required by May 2027. Gap: No analytical methods available to measure SPM emissions. Solution: Draft SPERC-based approac...
Case Studies on Reliability and Relevance Considerations during Validation of NAMs

Case Studies on Reliability and Relevance Considerations during Validation of NAMs

Why?Validation of NAMs is often overlooked despite its importance for regulatory use. Traditional validation methods are less suitable for NAMs, which focus on key events rather than apical...
Event
26.01.2016

Advances in consumer exposure science: Data, Modelling and Aggregate Exposure Assessment

01 December 2015, Park Inn Brussels Midi, Brussels, Belgium POSTPONED to 26th January 2016

This Workshop was originally scheduled to take place 01 December 2015 but due to the security alert in Brussels has been moved to 26 January 2016

Background

Although exposure-driven risk assessment has long been included in the toxicological and safety assessment of chemicals, advances in Toxicology in the 21st Century now highlight that exposure assessment is crucial.  Describing external and internal human exposure dose through modelling facilitates the targeted use of emerging toxicological tools for safety assessments.  Benefits of reliable exposure assessments include:

  • Accurate estimation of exposure.  This reduces uncertainty, thereby enabling risk assessment to be a truer reflection of the actual situation.
  • Improved integrity of the assessment by enabling targeted and prioritised focus on the populations exposed to the greatest risks.
  • Preventing/reducing the need for animal testing.
  • Implementing refined approaches to exposure assessment requires consideration of:
    - Data availability.
    - Specialised tools, data sets and computational power.
    - Standard approaches for the collection and sharing of appropriate data on consumer exposure.
    - Criteria for selecting optimal exposure databases and modelling tools available.

Aims

1) Present and review the current state of consumer exposure science by examining data needs, sources (including novel data sources), tools, gaps and the latest innovations.

2) Develop consensus on key gaps that should be filled and identify what the major research needs are, including how to address aggregate consumer exposure.

3) With the help of case studies, examine the potential for the refinement of exposure assessment using appropriate tools and techniques which are fit for purpose.

Structure

The workshop consists of a series of 20-minute talks followed by syndicate sessions (typically 10 people each) in which syndicate groups work with a number of fixed questions.

Organising Committee

Madeleine Laffont, ECETOC                                      Mark Pemberton, Systox

Chris Money, Cynara Consulting                               Carlos Rodriguez, P&G

Cian O’Mahony, Creme Global                                 Sarah Tozer, P&G