Welcome to Talia Neal-Walthall
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Welcome to Talia Neal-Walthall

We are pleased to welcome Talia Neal-Walthall to ECETOC as a secondee. Talia joins us to work on topics related to exposure, an area central to much of our current scientific programme. She will be wi...
September 2026 news from the Sec Gen
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September 2026 news from the Sec Gen

Dear members and colleagues,As we move through the year, there is a good deal to share. This has been a busy period for ECETOC, with changes to our team, our governance, and the work ahead. Let me...
HSSD Tool

HSSD Tool

This software was developed by a consortium of partners to facilitate the uptake of novel approaches to estimate aquatic threshold concentrations (e.g. the concentration at which 5% of the species are exposed above their EC50, HC5).
The Human Exposure Assessment Tools Database (heatDB)

The Human Exposure Assessment Tools Database (heatDB)

heatdb is a public directory of exposure data sources as well as available tools for exposure
NanoApp

NanoApp

ECETOC’s NanoApp is a tool designed to define the boundaries of sets of similar nanoforms and to generate a justification for the REACH registration.
Targeted Risk Assessment (TRA)

Targeted Risk Assessment (TRA)

The Targeted Risk Assessment (TRA) estimates exposures to workers, consumers and the environment that arise during a series of events.
TRA Task Force – Worker branch

TRA Task Force – Worker branch

Why? The Worker TRA Task Force has been active since 2019, delivering projects that advance the scientific basis of the Worker Targeted Risk Assessment (TRA) tool. Its overarching objective is to e...
Immunotoxicity assessment: Addressing Challenges and Advancing Methodologies [Workshop → Task Force]​

Immunotoxicity assessment: Addressing Challenges and Advancing Methodologies [Workshop → Task Force]​

Why?Regulatory assessment of immunotoxic properties of chemicals is a complex and challenging task​ Limited regulatory guidance exists​ Lack of industry and regulatory knowledge​...
Chronic fish case studies towards an IATA

Chronic fish case studies towards an IATA

Why?Hazard and safety assessments for the pelagic compartment often rely on in vivo studies using a single fish species, raising ethical concerns and uncertainty in terms of extrapolation....
Task Force
02.10.2024

Plastic Additives – Chemical risk assessment in the linear and circular plastic economy

Why?

Plastic additives and plastic-associated chemicals are a topic of great interest for the negotiations of the Internationally Legal Binding Instrument to End Plastic Waste (‘ILBI’). Developing risk-based solutions that are applicable to the circumstances unique to chemicals in polymer matrices and their increased recyclability is critical to ensure safe use.

The scientific work is to provide the background to regulators and stakeholders to conduct risk assessments on chemicals associated with plastic. The work will eventually lead to the development a framework specifically addressing the unique challenges associated with polymers in the linear and circular economy.

How

We propose a project to assess and advance chemical risk assessment to support the plastic circular economy.
As outlined in a briefing paper submitted to INC-5 in November 2024, the TF proposes to review risk assessment principles currently applied to plastic chemical additives and assess the considerations needed for circularity. Work previously conducted by the ICCA working group can serve as background material for experts.

  • Key Focus Areas:
  • Current state of the science on risk assessments of additives: What approaches do we have in place today to conduct risk assessments for additives in polymers? What can we achieve with what we have? What are the gaps?
  • Setting the scope of Additives in Circular economy – what are the challenges as we consider use of polymers after they are recycled?
    • Special considerations for polymeric materials
    • What are the gaps in understanding for chemicals in polymers, briefly contrasting to other materials (e.g., paper, glass, etc.)

Prepare 1st manuscript for publication.

Subsequently other related activities could be pursued:

Phase 2: Develop research projects aligned to the challenges identified in phase 1 to fill the gaps in knowledge or data availability

Phase 3: Prepare additional manuscript(s) applying risk assessment principles to plastic associated chemicals (e.g., non-intentionally added substances, unknown breakdown products, etc.) and relevant case studies

Deliverable

  • Scientific briefing paper for INC-5 in November 2024​
  • Manuscript 1: State-of-the-Science, application of additives to polymers, gap analysis, and potential solutions​
  • Manuscript 2: Risk assessment of additives in plastics in complex scenarios, such as recycling/circularity including case studies

Timeline

We propose a task force to advance risk assessment for plastic related chemicals (e.g., additives) to support the circular economy:

  • November 2024: Briefing paper for INC-5 
  • Q1 2025: Submit a recommendation to the ECETOC Scientific Committee of potential follow up activities, e.g.:
    • Develop research projects aligned to the challenges identified in phase 1 to fill the gaps in knowledge or data availability (12-48 months)
    • Prepare additional manuscript(s) outlining a risk-based framework to apply risk assessment principles to novel issues of plastic associated chemicals (e.g., NIAS) in the circular economy (18 months).