Chronic fish case studies towards an IATA

Why

• Hazard and safety assessments for the pelagic compartment often rely on in vivo studies using a single fish species, raising ethical concerns and uncertainty in terms of extrapolation.
• An Integrated Approach to Testing and Assessment (IATA) for chronic fish toxicity does not currently exist.

Objectives

• ECETOC Advisory Panel to work in liaison with contracted consultant to develop case studies, leveraging NAMs, to help shape future chronic fish toxicity IATA.

Timeline and Deliverables

• Timeline: end Q3 2025 - Q3 2027.
• Deliverables: Peer-reviewed manuscript(s) on case study findings, including proposed actions towards IATA.

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