2024 New Year message from the Secretary General
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2024 New Year message from the Secretary General

Dear ECETOC Members and Stakeholders, As we bid farewell to the successes of 2023, I am delighted to extend my warmest greetings all of you as we step into 2024. Last year was marked by signific...
ECETOC Task Force proposes a science-based testing strategy to predict if a chemical has the potential to disrupt the thyroid hormone system in humans
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ECETOC Task Force proposes a science-based testing strategy to predict if a chemical has the potential to disrupt the thyroid hormone system in humans

The ECETOC Thyroxine (T4) Task Force has developed a new science-based tiered testing strategy that aims to predict if substances have the potential to significantly disrupt the thyroid hormone sy...
HSSD Tool

HSSD Tool

This software was developed by a consortium of partners to facilitate the uptake of novel approaches to estimate aquatic threshold concentrations (e.g. the concentration at which 5% of the species are exposed above their EC50, HC5).
The Human Exposure Assessment Tools Database (heatDB)

The Human Exposure Assessment Tools Database (heatDB)

heatdb is a public directory of exposure data sources as well as available tools for exposure
NanoApp

NanoApp

ECETOC’s NanoApp is a tool designed to define the boundaries of sets of similar nanoforms and to generate a justification for the REACH registration.
Targeted Risk Assessment (TRA)

Targeted Risk Assessment (TRA)

The Targeted Risk Assessment (TRA) estimates exposures to workers, consumers and the environment that arise during a series of events.
Endocrine Disruption

Endocrine Disruption

In December 2016, in response to the ‘Outline of draft Guidance Document for the implementation of the hazard-based criteria to identify endocrine disruptors’, published by ECHA and EFSA in Dece...
Guidance Document for the Extended One-Generation Reproduction Toxicity Study (OECD Test Guideline 443) (EOGRT)

Guidance Document for the Extended One-Generation Reproduction Toxicity Study (OECD Test Guideline 443) (EOGRT)

Terms of Reference Review the available literature on the sensitivity and specificity of including a second generation in reproductive toxicity testing. Define, if possible, the triggers to...
Targeted Risk Assessment: TRA Tool Steering Team

Targeted Risk Assessment: TRA Tool Steering Team

Introduction ECETOC initiated its targeted risk assessment (TRA) activity in 2001 and the first public version (v1) of the TRA exposure model was made available in 2004. Since then the TRA tool has...
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TRA – Download

The Targeted Risk Assessment (TRA) tool is available in three different versions:
  • The Integrated tool, which allows users to estimate exposure/risk for workers, consumers and environment
  • The Standalone Consumer tool, which allows users to estimate exposure/risk for consumers
  • The Standalone Worker tool, which allows users to estimate exposure/risk for workers

Download and Installation

1. Click the “download icon” for the required tool and complete the request form.

2. An email will be sent to you containing a download link. This should arrive within a few minutes but if not then please check your spam mail settings and spam/junk mail boxes.

3. Download the zip file with the link provided in the email.

4. Unzip the file to the folder where you will use the tool; keep the original zip so that you can create a fresh installation when necessary; any folder should only contain 1 copy of the tool.

5. Please refer to the User Guides for guidance on starting and exiting the tools

Please note that ECETOC does not operate a help desk. For help with using the tool, please refer to the Users manual and FAQ and to the resources available as Background documentation and further reading.

Please email us via the following link if you need further help with the download and installation of the tool: info@ecetoc.org

DISCLAIMER: please note that the tool is provided for personal use only. It should not be copied or forwarded to third parties. The tool has been subjected to thorough testing. Despite this, ECETOC does not guarantee that the ECETOC TRA tool works error-free. ECETOC is making this tool available for users to aid them in the risk assessment of their materials. ECETOC offers no warranty either to the reliability of the tool and of the provided information or to the conclusions or assumptions made by any user on the basis of the use of this tool or the use of such information. All usage is at the discretion of the user and ECETOC is not liable for any consequences resulting from such use..