toxic

• 21 November 2012

  TR 116 – Category approaches, read-across, (Q)SAR

  TR 116 : Category approaches, read-across, (Q)SAR | 21 November 2012 Background An accepted practice for the assessment of human health and environmental […]

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  • Tags : (Q)SAR, analogue, approach, Assessment, category, Ecotoxicity, environmental, experimental, expert, generic, in vitro, in vivo test, Industry, mammalian, metal, narcotic, non-testing approach, organic, PBPK, product, REACh, read-across, Risk assessment, safety, skin, studies, target chemicals, toxic, Toxicity
• 31 July 2012

  TR 115 – Effects of Chemical Co-exposures at Doses Relevant for Human Safety Assessments

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  • Tags : acid, acute, carcinogenicity, chemical, chemical regulation, chronic, component, concentration, developmental, dissimilar chemicals, dose, endocrine, environmental, exposure, in vitro, mammalian, melamine, Mixture, NOAEL, Oestrogen, organ, organic, pyrethrin, Risk assessment, safety margin, similar chemicals, substance, synergistic, testing, toxic, Toxicity, Toxicology, Treatment, Tumour
• 29 October 2011

  TR 111 – Development of guidance for assessing the impact of mixtures of chemicals in the aquatic environment

  TR 111 : Development of guidance for assessing the impact of mixtures of chemicals in the aquatic environment | October 2011 ISSN-0773-8072-111 (print) […]

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  • Tags : chemical, Chemical preparation, Composition, concentration, Consumer, Discharge, Ecotoxicology, Effluent, environment, environmental risk, exposure, Industrial activity, metal, Mixture, pharmaceuticals, Preparation, toxic
• 29 December 2008

  TR 103 – Toxicity of Possible Impurities and By-products in Fluorocarbon Products

  TR 103 : Toxicity of Possible Impurities and By-products in Fluorocarbon Products | December 2008 This report has been produced to accompany the […]

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  • Tags : by-products, commodity chemicals, Compound, fluorocarbons, halogenated, hydrochlorofluorocarbon, hydrofluorocarbon, impurities, Joint Assessment of Commodity Chemicals (JACC), Lethal, Material, Molecule, Organisation, physico-chemical properties, product, purity, REACh, Saturated, substance, toxic, Toxicant, Toxicity, Toxicology, unsaturated
• 29 October 2006

  TR 101 – Guidance for setting occupational exposure limits: Emphasis on data-poor substances

  TR 101 : Guidance for setting occupational exposure limits: Emphasis on data-poor substances | October 2006 In the absence of sound human exposure […]

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  • Tags : air concentrations, air-water partition coefficient, Animal, animal data, Carcinogenic, chemical food contaminants, chemical properties, chemical safety assessment, chemical safety report, chemical substance, chronic, concentration, distributionexpert, exposed, exposure, hazard banding, hazard categories, health, homologous, human data, hydrocarbon, inhalation, integration, Lethal, Liquid, LOAEL, mammalian, Method, MTD, mutagenic, NOAEL, NTP, Occupational exposure limit (OEL), octanol-air partition coefficient, oral, overexposure, person, procedure, progeny, protection, public health risk, REACh, read-across approach, reprotoxic, respiratory dose, risk assessor, risk phrase, scientist, sensory irritation, solid, solvent, studies, substance, targeted risk, toxic, Toxicity, Toxicological, worker, workplace
• 28 September 2006

  JACC Report 51 – Synthetic Amorphous Silica

  JACC 051 : Synthetic Amorphous Silica | September 2006 This report has been produced as part of the ECETOC Joint Assessment of Commodity […]

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  • Tags : Absorption, acute inhalation toxicity, adverse effects, agglomerates, airborne concentrations, alkali metal silicate, American Conference for Governmental Industrial Hygienists, amorphous silicas, aqueous systems, bioavailable, bone marrow, cancer, carcinogenicity, chromatography, chromosomal aberrations, chronic toxicity, Condensation, contact allergy, cosmetics, cracking, dermal irritation, dermal toxicity, developmental toxicity, diatoms, dichlorodimethyl, DNA synthesis, dryness, Ecotoxicology, elastomers, Emphysema, environment, Environmental fate, Epidemiology, Erythema, Excreted, experimental animals, eye irritant, Eye Irritation, fertility, focal fibrosis, Gas chromatography, genotoxic, Genotoxicity, granuloma, human risk assessment, Hydrophilic, hydrophobic, in vitro, in vivo, inhalable, inhalation, inks, International Agency for Research on Cancer, Intravenous injection, intrinsic toxicity, LOAEL, Long-term inhalation, long-term respiratory health effects, lung collagen, lung collagen content, lung inflammation. lung tumours, man-made SAS, mechanical irritation, methyl, mice, Morphology, mortality, mutagenic, natural flux, neoplasms, NOAEL, non-crystalline, non-toxic, oral, oral administration, particle size, peripheral, pharmaceuticals, pneumonia, precipitated silica, pulmonary function, pulmonary inflammation, pulmonary retention, pyrogenic silica, rats, reproductive organs, respirable, respiratory distress, SAS, SAS dust, Sex, Silica, silica gel, Silicon dioxide, silicon metal, Skin Irritation, sodium chloride, solubility, spectroscopy, subchronic, subcutaneously, Suffocation, surface treatment, survival rate, synthetic amorphous silica, thermal route, tissue reaction, toxic, Toxicology, tumours, weight gain, wet route
• 28 November 2005

  JACC Report 49 – Vinylidene Fluoride

  JACC 049 : Vinylidene Fluoride (CAS No. 75-38-7) | November 2005 This report has been produced as part of the ECETOC Joint Assessment […]

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  • Tags : Acute toxicity, American Conference of Governmental Industrial Hygienists, Assessment, atmosphere, Atmospheric degradation, bioaccumulation, biodegradation, biomagnification, body weight, breakdown, carbon dioxide, Carbonyl fluoride, Cardiac sensitisation, chlorotrifluoroethylene, citric acid cycle, clinical chemistry, colourless odourless flammable gas, copolymers, depletion, Ecotoxicity, embryotoxic, environment, Environmental fate, Environmental protection agency, EPA, exposure, Eye Irritation, fertility, fluoroacetic acid, foetotoxic, foetotoxic or teratogenic effect, food chain, formaldehyde, global warming, ground-level ozone, haematology, Hexafluoropropylene, HFC-143a, high volatility, Histopathology, hydroxyl radicals, impaired spermatogenesis, in vitro, in vivo, inhalation studies, kidneys, limited solubility, lipomas, liposarcomas, mineralisation, Mouse, NOAEL, organ weights, partition, polyvinylidene fluoride, rats, regenerative changes, reproduction, Rhinitis, Sex, soil, Soluble, stratospheric ozone, teratogenic, teratology study, Terrestrial organisms, testes, Tetrafluoroethylene, toxic, Toxicity, Troposphere, tropospheric ozone, urinary fluoride excretion, VDF, vinylidene fluoride, vomeronasal organ
• 28 May 2005

  JACC Report 47 – 1,1-Dichloro-2,2,2-trifluoroethane (HCFC-123) Third edition

  JACC 047 : 1,1-Dichloro-2,2,2-trifluoroethane (HCFC-123)CAS No. 306-83-2 (Third Edition) | July 2005 This report has been produced as part of the ECETOC Joint […]

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  • Tags : air levels, air-conditioning, algae, Aquatic organisms, Aquatic toxicity, benign tumours, bio-concentrate, Biodegradable, body weight gain, cardiac arrhythmia, cell transformation, central nervous system, chromosome aberration, Clastogenic activity, CNS, concurrent exposure, Copenhagen Amendment, Depression, developmental toxicity, Dichloro-2 2 2-trifluoroethane, dogs, exposure groups, Eye Irritation, fish, genotoxic, global warming potential, Growth, guinea pigs, hamster, HCFC-123, HCFC-124, hepatic, hepatocellular adenomas, HFC-125, hormonal disturbances, human exposure, human lymphocytes, hygiene practices, immuno-blotting, in vivo, lesions, life threatening, liver disease, liver lesions, LOAEL, lower body weight, Montreal Protocol, necrosis, neonates, occupational exposure., peroxisome proliferation, proliferation, rabbits, radicals, Rat, Refrigerant, reproductive performance, Soluble, strain, testicular tumours, Tetrachloroethylene, toxic, trifluoroacetic acid, trifluoroacetyl chloride, β-oxidation