NOAEL

• 31 July 2012

  TR 115 – Effects of Chemical Co-exposures at Doses Relevant for Human Safety Assessments

  • Read abstract
  • Download PDF
  • Tags : acid, acute, carcinogenicity, chemical, chemical regulation, chronic, component, concentration, developmental, dissimilar chemicals, dose, endocrine, environmental, exposure, in vitro, mammalian, melamine, Mixture, NOAEL, Oestrogen, organ, organic, pyrethrin, Risk assessment, safety margin, similar chemicals, substance, synergistic, testing, toxic, Toxicity, Toxicology, Treatment, Tumour
• 28 July 2008

  Workshop Report 11 – Workshop on the Application of ‘Omics in Toxicology and Ecotoxicology: Case Studies and Risk Assessment

  WR 11 : Workshop on the Application of ‘Omics in Toxicology and Ecotoxicology: Case Studies and Risk Assessment | July 2008 To review […]

  • Read abstract
  • Download PDF
  • Tags : biological, cellular, chemical, chemical risk, chemical safety, Chemical substances, chronic, control, ecological risk assessment, environment, environmental, exposure, fish, gene expression, genomic science, genomics data, guidance, Industry, NOAEL, omic, organism, parameter, pathway, Pharmaceutical, pharmaceutical industry, Population, profile, Risk assessment, science, scientist, standard, study, technology, Toxicant, Toxicity, Toxicology, Tumour
• 28 September 2007

  JACC Report 53 – Cyanides of Hydrogen, Sodium and Potassium, and Acetone Cyanohydrin vol.II

  JACC 053 Vol II : Cyanides of Hydrogen, Sodium and Potassium, and Acetone Cyanohydrin (CAS No. 74-90-8, 143-33-9, 151-50-8 and 75-86-5), Volumes I […]

  • Read abstract
  • Download PDF
  • Tags : 1 1-dichloroethylene, 1 1-Difluoroethane, Acute toxicity, adrenaline, Allergy, American Industrial Hygiene Association, Ames test, Aquatic organisms, Atmospheric degradation, BHK21, Cardiac sensitisation, Chlorofluorocarbon, chromatography, chromosomal aberration, CO2, developmental toxicity, Ecotoxicity, environment, environmental toxicity, exposure, flammable colourless gas, formaldehyde, Genomics, genotoxic potential, global warming potential, HF, HFC, HFC-143a, Human volunteers, in vitro, in vivo, inhalation, lymphocytes, metabolite, method of exposure, NOAEL, occupational exposure., Ozone depletion, PAFT, physico-chemical properties, rabbit, rats, Refrigeration systems, reproductive effects, Salmonella typhimurium, Sex, stratospheric ozone layer, Styles Assay, testicular weight, Toxicity, Toxicology, trifluoroacetaldehyde, Trifluoroethane, Trifluoroethanol, volatilise, whole-body
• 28 September 2007

  JACC Report 53 – Cyanides of Hydrogen, Sodium and Potassium, and Acetone Cyanohydrin vol.I

  JACC 053 Vol I : Cyanides of Hydrogen, Sodium and Potassium, and Acetone Cyanohydrin (CAS No. 74-90-8, 143-33-9, 151-50-8 and 75-86-5), Volumes I […]

  • Read abstract
  • Download PDF
  • Tags : 1 1-dichloroethylene, 1 1-Difluoroethane, Acute toxicity, adrenaline, Allergy, American Industrial Hygiene Association, Ames test, Aquatic organisms, Atmospheric degradation, BHK21, Cardiac sensitisation, Chlorofluorocarbon, chromatography, chromosomal aberration, CO2, developmental toxicity, Ecotoxicity, environment, environmental toxicity, exposure, flammable colourless gas, formaldehyde, Genomics, genotoxic potential, global warming potential, HF, HFC-143a, Human volunteers, in vitro, in vivo, inhalation, lymphocytes, metabolite, method of exposure, NOAEL, occupational exposure., Ozone depletion, PAFT, physico-chemical properties, rabbit, rats, Refrigeration systems, reproductive effects, Salmonella typhimurium, Sex, stratospheric ozone layer, Styles Assay, testicular weight, Toxicity, Toxicology, trifluoroacetaldehyde, Trifluoroethane, Trifluoroethanol, volatilise, whole-body
• 29 October 2006

  TR 101 – Guidance for setting occupational exposure limits: Emphasis on data-poor substances

  TR 101 : Guidance for setting occupational exposure limits: Emphasis on data-poor substances | October 2006 In the absence of sound human exposure […]

  • Read abstract
  • Download PDF
  • Tags : air concentrations, air-water partition coefficient, Animal, animal data, Carcinogenic, chemical food contaminants, chemical properties, chemical safety assessment, chemical safety report, chemical substance, chronic, concentration, distributionexpert, exposed, exposure, hazard banding, hazard categories, health, homologous, human data, hydrocarbon, inhalation, integration, Lethal, Liquid, LOAEL, mammalian, Method, MTD, mutagenic, NOAEL, NTP, Occupational exposure limit (OEL), octanol-air partition coefficient, oral, overexposure, person, procedure, progeny, protection, public health risk, REACh, read-across approach, reprotoxic, respiratory dose, risk assessor, risk phrase, scientist, sensory irritation, solid, solvent, studies, substance, targeted risk, toxic, Toxicity, Toxicological, worker, workplace
• 28 September 2006

  JACC Report 51 – Synthetic Amorphous Silica

  JACC 051 : Synthetic Amorphous Silica | September 2006 This report has been produced as part of the ECETOC Joint Assessment of Commodity […]

  • Read abstract
  • Download PDF
  • Tags : Absorption, acute inhalation toxicity, adverse effects, agglomerates, airborne concentrations, alkali metal silicate, American Conference for Governmental Industrial Hygienists, amorphous silicas, aqueous systems, bioavailable, bone marrow, cancer, carcinogenicity, chromatography, chromosomal aberrations, chronic toxicity, Condensation, contact allergy, cosmetics, cracking, dermal irritation, dermal toxicity, developmental toxicity, diatoms, dichlorodimethyl, DNA synthesis, dryness, Ecotoxicology, elastomers, Emphysema, environment, Environmental fate, Epidemiology, Erythema, Excreted, experimental animals, eye irritant, Eye Irritation, fertility, focal fibrosis, Gas chromatography, genotoxic, Genotoxicity, granuloma, human risk assessment, Hydrophilic, hydrophobic, in vitro, in vivo, inhalable, inhalation, inks, International Agency for Research on Cancer, Intravenous injection, intrinsic toxicity, LOAEL, Long-term inhalation, long-term respiratory health effects, lung collagen, lung collagen content, lung inflammation. lung tumours, man-made SAS, mechanical irritation, methyl, mice, Morphology, mortality, mutagenic, natural flux, neoplasms, NOAEL, non-crystalline, non-toxic, oral, oral administration, particle size, peripheral, pharmaceuticals, pneumonia, precipitated silica, pulmonary function, pulmonary inflammation, pulmonary retention, pyrogenic silica, rats, reproductive organs, respirable, respiratory distress, SAS, SAS dust, Sex, Silica, silica gel, Silicon dioxide, silicon metal, Skin Irritation, sodium chloride, solubility, spectroscopy, subchronic, subcutaneously, Suffocation, surface treatment, survival rate, synthetic amorphous silica, thermal route, tissue reaction, toxic, Toxicology, tumours, weight gain, wet route
• 28 November 2005

  JACC Report 49 – Vinylidene Fluoride

  JACC 049 : Vinylidene Fluoride (CAS No. 75-38-7) | November 2005 This report has been produced as part of the ECETOC Joint Assessment […]

  • Read abstract
  • Download PDF
  • Tags : Acute toxicity, American Conference of Governmental Industrial Hygienists, Assessment, atmosphere, Atmospheric degradation, bioaccumulation, biodegradation, biomagnification, body weight, breakdown, carbon dioxide, Carbonyl fluoride, Cardiac sensitisation, chlorotrifluoroethylene, citric acid cycle, clinical chemistry, colourless odourless flammable gas, copolymers, depletion, Ecotoxicity, embryotoxic, environment, Environmental fate, Environmental protection agency, EPA, exposure, Eye Irritation, fertility, fluoroacetic acid, foetotoxic, foetotoxic or teratogenic effect, food chain, formaldehyde, global warming, ground-level ozone, haematology, Hexafluoropropylene, HFC-143a, high volatility, Histopathology, hydroxyl radicals, impaired spermatogenesis, in vitro, in vivo, inhalation studies, kidneys, limited solubility, lipomas, liposarcomas, mineralisation, Mouse, NOAEL, organ weights, partition, polyvinylidene fluoride, rats, regenerative changes, reproduction, Rhinitis, Sex, soil, Soluble, stratospheric ozone, teratogenic, teratology study, Terrestrial organisms, testes, Tetrafluoroethylene, toxic, Toxicity, Troposphere, tropospheric ozone, urinary fluoride excretion, VDF, vinylidene fluoride, vomeronasal organ
• 28 September 2005

  JACC Report 48 – Hexafluoropropylene

  JACC 048 : Hexafluoropropylene (CAS No. 116-15-4) | October 2005 This report has been produced as part of the ECETOC Joint Assessment of […]

  • Read abstract
  • Download PDF
  • Tags : Acute toxicity, American Conference of Governmental Industrial Hygienists, atmospheric breakdown, bioaccumulate, biota, cancer, carbon dioxide, carcinogenicity, chronic toxicity, clonic spasms, closed systems, consumer exposure, developmental toxicity, developmental toxicity studies, DNA synthesis, Ecotoxicity, environment, environmental risk, exposure limit, fluoro-elastomers, Fluoropolymers, Genotoxicity, German MAK Commission, global warming, Hexafluoropropylene, HFP, hydrogen fluoride, kidney, mice, nephrotoxicity, NOAEL, occupational exposure., partition, perfluoropolyether functional fluids, photolysis, polymeric products, rats, reaction, relative kidney weight, relative spleen weight, reproductive system, Soluble, Synthesis, target organ, Tetrafluoroethylene, Toxicity, trifluoroacetic acid
• 29 July 2005

  TR 096 – Trends in Children’s Health and the Role of Chemicals

  TR 096 : Trends in Children’s Health and the Role of Chemicals | July 2005 Children, compared to adults, can be more sensitive, […]

  • Read abstract
  • Download PDF
  • Tags : ‘blanket’ approach, ADHD, adverse effects, ambient air pollutants, Asthma, Atopic dermatitis, autism, biomarkers, chemical contaminants, chemical insults, chemical toxicity, chemotherapeutic agents, chemotherapy, childhood cancer, cryptorchidism, diagnostic criteria, Early exposure, Ecotoxicology, environmental factors, Exposure assessment, exposure to antigens, exposure to chemicals, food additives, gene expression, Genetic factors, geographic heterogeneity, Hygiene hypothesis, hypospadias, leukaemia, lymphoma, neurodevelopmental disorders, Nickel, no observed adverse effect level, NOAEL, otitis media, patterns of exposure, pharmacokinetic characteristics, Radiation, reproductive effects, respiratory diseases, skin barrier function, Sperm quality, toxicogenomics, volatile organic chemicals, windows of vulnerability
• 28 February 2003

  TR 086 – Derivation of Assessment Factors for Human Health Risk Assessment

  TR 086 : Derivation of Assessment Factors for Human Health Risk Assessment | February 2003 In general, the risks to human health posed […]

  • Read abstract
  • Download PDF
  • Tags : allometric scaling, Benchmark dose, chronic exposure, chronic toxicity, default assessment factors, dermal permeation, Exposure assessment, extrapolation elements, general industrial chemicals, human health risk, interspecies, intraspecies, linear accumulation, linear bioaccumulation, LOAEL, local effects, lowest observed adverse effect level, metabolites, microencapsulation, no observed adverse effect level, NOAEL, numerical values, physico-chemical properties, Reference dose, Risk assessment, route to route extrapolation, safe dose, systemic effects, toxicological endpoints