in vitro

• 21 November 2012

  TR 116 – Category approaches, read-across, (Q)SAR

  TR 116 : Category approaches, read-across, (Q)SAR | 21 November 2012 Background An accepted practice for the assessment of human health and environmental […]

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  • Tags : (Q)SAR, analogue, approach, Assessment, category, Ecotoxicity, environmental, experimental, expert, generic, in vitro, in vivo test, Industry, mammalian, metal, narcotic, non-testing approach, organic, PBPK, product, REACh, read-across, Risk assessment, safety, skin, studies, target chemicals, toxic, Toxicity
• 31 July 2012

  TR 115 – Effects of Chemical Co-exposures at Doses Relevant for Human Safety Assessments

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  • Tags : acid, acute, carcinogenicity, chemical, chemical regulation, chronic, component, concentration, developmental, dissimilar chemicals, dose, endocrine, environmental, exposure, in vitro, mammalian, melamine, Mixture, NOAEL, Oestrogen, organ, organic, pyrethrin, Risk assessment, safety margin, similar chemicals, substance, synergistic, testing, toxic, Toxicity, Toxicology, Treatment, Tumour
• 28 December 2011

  JACC Report 55 – Linear Polydimethylsiloxanes second edition

  JACC 055 : Linear Polydimethylsiloxanes CAS No. 63148-62-9 (Second Edition) | December 2011 ISSN-0773-6339-55 print ISSN-2079-1496-55 online D-2011-3001-220 EXECUTIVE SUMMARY This report presents […]

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  • Tags : Adsorption, Aquatic organisms, Autoimmune disorders, Breast cancer, Breast implant, cancer, carbon dioxide, carcinogenicity, Dermal contact, Dermatology, Dimethylsilanediol, DMSD, European Union, Extraction efficiency, fibromyalgia, Gas chromatography, Heat transfer, Human health, hydrophobic chemicals, in vitro, in vivo, Inorganic silicate, Insects, Insoluble, Linear polydimethylsiloxanes, mammaplasty, MS, muscular rheumatism, mutagenic, Mutagenic activity, Non-volatile, Occupational exposure limit, OECD, Ophthalmological problems, Oral ingestion, pharmaceutical applications, Polydimethylsiloxane, Radiation, rheumatic disease, rheumatoid arthritis, sarcomas, Sewage treatment, silicone oil, Silicones, Skin irritant, skin sensitiser, Soil organisms, sorption, spectroscopy, Swallowed PDMS, Toxicity, Toxicology, Urological problems, US FDA, wastewater treatment
• 29 November 2011

  Workshop Report 22 – Workshop on Combined Exposure to Chemicals

  WR 22 : Workshop on Combined Exposure to Chemicals | October 2011 Workshop on Combined Exposure to Chemicals. 11-12 July 2011, Berlin Published […]

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  • Tags : aquatic environment, breakout groups, chemical mixtures, Co-exposure, Environmental risk assessment, Exposure assessment, in vitro, Maximum cumulative ratio, MRC, NOEL, Risk assessment, Synergy, Toxicity, Toxicology, Treshold of toxicological concern, TTC, wastewater treatment, Wastewater treatment plants, WHO/IPCS framework, WWTs
• 28 June 2008

  JACC Report 54 – Difluoromethane (Second Edition)

  JACC 054 : Difluoromethane (HFC-32) CAS No. 75-10-5 (Second Edition) | June 2008 This report has been produced as part of the ECETOC […]

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  • Tags : adverse health effects, American Industrial Hygiene Association, aquatic environment, carbon dioxide, carboxyhaemoglobin, Carcinogenic, Cardiac sensitisation, colourless, difluoromethane, Ecotoxicity, Environmental fate, fertility, flammable gas, foetotoxicity, genotoxic, global warming, greenhouse gas, HFC-32, hydrofluorocarbons, hydrogen fluoride, in vitro, in vivo, limb tremors, Maternal toxicity, metabolised, mortality, mutagenic, oxidative pathway, Programme for Alternative Fluorocarbon Toxicity Testing, reduced breathing rate, Refrigerants, Sex, stratospheric ozone, teratogenic, toxic effects, Toxicity, urinalysis
• 28 September 2007

  JACC Report 53 – Cyanides of Hydrogen, Sodium and Potassium, and Acetone Cyanohydrin vol.II

  JACC 053 Vol II : Cyanides of Hydrogen, Sodium and Potassium, and Acetone Cyanohydrin (CAS No. 74-90-8, 143-33-9, 151-50-8 and 75-86-5), Volumes I […]

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  • Tags : 1 1-dichloroethylene, 1 1-Difluoroethane, Acute toxicity, adrenaline, Allergy, American Industrial Hygiene Association, Ames test, Aquatic organisms, Atmospheric degradation, BHK21, Cardiac sensitisation, Chlorofluorocarbon, chromatography, chromosomal aberration, CO2, developmental toxicity, Ecotoxicity, environment, environmental toxicity, exposure, flammable colourless gas, formaldehyde, Genomics, genotoxic potential, global warming potential, HF, HFC, HFC-143a, Human volunteers, in vitro, in vivo, inhalation, lymphocytes, metabolite, method of exposure, NOAEL, occupational exposure., Ozone depletion, PAFT, physico-chemical properties, rabbit, rats, Refrigeration systems, reproductive effects, Salmonella typhimurium, Sex, stratospheric ozone layer, Styles Assay, testicular weight, Toxicity, Toxicology, trifluoroacetaldehyde, Trifluoroethane, Trifluoroethanol, volatilise, whole-body
• 28 September 2007

  JACC Report 53 – Cyanides of Hydrogen, Sodium and Potassium, and Acetone Cyanohydrin vol.I

  JACC 053 Vol I : Cyanides of Hydrogen, Sodium and Potassium, and Acetone Cyanohydrin (CAS No. 74-90-8, 143-33-9, 151-50-8 and 75-86-5), Volumes I […]

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  • Tags : 1 1-dichloroethylene, 1 1-Difluoroethane, Acute toxicity, adrenaline, Allergy, American Industrial Hygiene Association, Ames test, Aquatic organisms, Atmospheric degradation, BHK21, Cardiac sensitisation, Chlorofluorocarbon, chromatography, chromosomal aberration, CO2, developmental toxicity, Ecotoxicity, environment, environmental toxicity, exposure, flammable colourless gas, formaldehyde, Genomics, genotoxic potential, global warming potential, HF, HFC-143a, Human volunteers, in vitro, in vivo, inhalation, lymphocytes, metabolite, method of exposure, NOAEL, occupational exposure., Ozone depletion, PAFT, physico-chemical properties, rabbit, rats, Refrigeration systems, reproductive effects, Salmonella typhimurium, Sex, stratospheric ozone layer, Styles Assay, testicular weight, Toxicity, Toxicology, trifluoroacetaldehyde, Trifluoroethane, Trifluoroethanol, volatilise, whole-body
• 28 September 2006

  Workshop Report 07 – Workshop on Testing Strategies to Establish the Safety of Nanomaterials

  WR 07 : Workshop on Testing Strategies to Establish the Safety of Nanomaterials | September 2006 Nanotechnology produces an increasing number of engineered […]

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  • Tags : agglomerates, aggregates, breakout groups, cardiovascular system, cell proliferation, central nervous system, chemical composition, cytotoxicity, dermal exposure, dermal uptake, dissolution, engineered nanoparticles, environmental impact, hazard potential, Histopathology, in vitro, in vivo, intratracheal instillation, methodologies, nanomaterial characterisation, nanomaterials, Nanomedicine, Nanotechnology, OECD, oxidative stress, potential systemic effects, Skin penetration, stratum corneum, surface characteristics, testing strategies, translocation
• 28 September 2006

  JACC Report 51 – Synthetic Amorphous Silica

  JACC 051 : Synthetic Amorphous Silica | September 2006 This report has been produced as part of the ECETOC Joint Assessment of Commodity […]

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  • Tags : Absorption, acute inhalation toxicity, adverse effects, agglomerates, airborne concentrations, alkali metal silicate, American Conference for Governmental Industrial Hygienists, amorphous silicas, aqueous systems, bioavailable, bone marrow, cancer, carcinogenicity, chromatography, chromosomal aberrations, chronic toxicity, Condensation, contact allergy, cosmetics, cracking, dermal irritation, dermal toxicity, developmental toxicity, diatoms, dichlorodimethyl, DNA synthesis, dryness, Ecotoxicology, elastomers, Emphysema, environment, Environmental fate, Epidemiology, Erythema, Excreted, experimental animals, eye irritant, Eye Irritation, fertility, focal fibrosis, Gas chromatography, genotoxic, Genotoxicity, granuloma, human risk assessment, Hydrophilic, hydrophobic, in vitro, in vivo, inhalable, inhalation, inks, International Agency for Research on Cancer, Intravenous injection, intrinsic toxicity, LOAEL, Long-term inhalation, long-term respiratory health effects, lung collagen, lung collagen content, lung inflammation. lung tumours, man-made SAS, mechanical irritation, methyl, mice, Morphology, mortality, mutagenic, natural flux, neoplasms, NOAEL, non-crystalline, non-toxic, oral, oral administration, particle size, peripheral, pharmaceuticals, pneumonia, precipitated silica, pulmonary function, pulmonary inflammation, pulmonary retention, pyrogenic silica, rats, reproductive organs, respirable, respiratory distress, SAS, SAS dust, Sex, Silica, silica gel, Silicon dioxide, silicon metal, Skin Irritation, sodium chloride, solubility, spectroscopy, subchronic, subcutaneously, Suffocation, surface treatment, survival rate, synthetic amorphous silica, thermal route, tissue reaction, toxic, Toxicology, tumours, weight gain, wet route
• 28 January 2006

  JACC Report 50 – 1,1,1,2-Tetrafluoroethane (HFC-134a) Second edition

  JACC 050 : 1,1,1,2-Tetrafluoroethane (HFC-134a) (CAS No. 811-97-2) (Second Edition) | January 2006 This report has been produced as part of the ECETOC […]

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  • Tags : 1 1 1 2-Tetrafluoroethane, Acute toxicity, adrenaline, adverse effects, air-conditioning, aquatic environment, Aquatic organisms, atmospheric concentration, Atmospheric degradation, atmospheric lifetime, bioaccumulation, biodegradation, biota, body weight gain, bromine, carbon dioxide, Cardiac sensitisation, cell adenoma, chemical, chemical properties, chlorine, Chlorofluorocarbon, chronic toxicity, control groups, corn oil, degradation, DNA synthesis, Ecotoxicity, environment, Environmental fate, Epinephrine, experimental animals, expired air, Eye Irritation, female rats, fertility, formic acid, gas, genotoxic, global warming potential, greenhouse effect, haematology, HFC-134a, hydrochlorofluorocarbons, hydrofluoric acid, hydroxyl radicals, hyperplasia, in vitro, in vivo, inhalation, irritation, male rats, Metabolism, metered dose inhalers, non flammable gas, non-neoplastic, occupational exposure., Ozone depletion, PAFT, partition, Programme for Alternative Fluorocarbon Toxicity Testing, Propellants, rats, Refrigeration, reproductive effects, Sex, Skin Irritation, Skin sensitisation, skin sensitiser, soil, sorption, spectroscopy, teratogenic, testicular Leydig, testicular Leydig cell hyperplasia, testosterone, Toxicity, trifluoroacetic acid, Troposphere, tumours